Cell prolifertion is a fundamental aspect of live. Cells reproduce by a series of coordinated events that is called the cell cycle. Our research goal is to understand the basic control of the cell cycle and its coordination within a multicellular organism. We use yeast (Saccharomyces cerevisiae) and the fruit fly (Drosophila) as model systems. Major projects focus on exit from mitosis, the regulation of the Ubiquitin Ligase APC/C (Anaphase-Promoting-Complex/Cyclosome) and control of special cell cycles during development