Publications PD Dr. Michael Bucher

C. Schmidt, K. Höcherl, F. Schweda, M. Bucher. Proinflammatory cytokines cause downregulation of renal chloride entry pathways during sepsis. Crit Care Med. 2007; 35: in press.

F. Kees, M. Bucher, F. Schweda, H. Gschaidmeier, L. Faerber, R. Seifert. Neoimmun versus Neoral: a bioequivalence study in healthy volunteers, and influence of a fat-rich meal on the bioavailability of Neoimmun. N-S Arch Pharmacol. 375: 393-399 (2007).

C. Schmidt, K. Höcherl, F. Schweda, A. Kurtz, M. Bucher. Regulation of renal sodium transporters during severe inflammation. J Am Soc Nephrol. 18: 1072-1083 (2007).

C. Schmidt, K. Höcherl, M. Bucher. Cytokine-mediated regulation of urea transporters during experimental endotoxemia. Am J Physiol. 2007; F1479-1489 (2007).

C. Schmidt, K. Höcherl, M. Bucher. Regulation of renal glucose transporters during severe inflammation. Am J Physiol. 292: F804-11 (2006).

K. Lotter, K. Höcherl, M. Bucher, F. Kees. In vivo efficacy of telithromycin on cytokine and nitric oxide formation in lipopolysaccharide-induced acute systemic inflammation in mice. J Antimicrob Chemother, 58: 615-621(2006).

F. Kees, M. Bucher, F. Schweda, H. Gschaidmeier, J. Burhenne, G. Mikus, L. Faerber. Comparative Bioavailability of the Microemulsion Formulation of Cyclosporine (Neoral) with a Generic Dispersion Formulation (Cicloral) in Young Healthy Male Volunteers. Ther Drug Monit, 28: 312-320 (2006).

M. Bucher, F. K. Kees, B. Meßmann, D. Lunz, S. Rath, M. Zelenka, H. J. Schlitt, J. Hobbhahn. Prostaglandin I₂ release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. Eur J Pharmacol, 536: 296-300 (2006).

Kees, F., Dittmar, M., Mair, G., Bucher, M. Cicloral versus Neoral: a bioequivalence study in healthy volunteers, and influence of a fat-rich meal on the bioavailability of Cicloral. Transplantation Proceedings, 36, 3234-3238 (2004).

Bucher, M. Expression vasokonstriktorischer Rezeptoren während experimenteller Endotoxämie. Anästh Intensivmed 45, 247-261 (2004).

Wagner, C. Vitzthum, H., Castrop, H., Schumacher, K., Bucher, M., Albertin, S., Coffman, T.M., Arendshorst, W.J., Kurtz, A. Differential regulation of renin and COX-2 expression in the renal cortex of C57Bl/6 mice. Pflugers Arch 447, 214-22 (2003).

Kees, F., Jehkul, A., Bucher, M., Mair, G., Kiermaier, J., Grobecker, H. Bioavailability of opipramol from a film-coated tablet, a sugar-coated tablet and an aqueous solution in healthy volunteers. Arzneimittelforschung 53, 87-92 (2003).

Bucher, M., Kees, F., Taeger, K., Kurtz, A. Cytokines down-regulate α₁-adrenergic receptor expression during endotoxemia. Crit Care Med 31, 566-71 (2003).

Ittner, K. P., Bucher, M., Zimmermann, M., Grobecker, H. E., Kramer, B. K., Taeger, K. Effect of three different doses of urapidil on blood glucose concentrations in the streptozotocin diabetic rat. Eur J Anaesthesiol 19, 504-9 (2002).

Hocherl, K., Dreher, F., Kurtz, A., Bucher, M. Cyclooxygenase-2 inhibition attenuates lipopolysaccharide-induced cardiovascular failure. Hypertension 40, 947-53 (2002).

Bucher, M., Taeger, K. Endothelin-receptor gene-expression in rat endotoxemia. Intensive Care Med 28, 642-7 (2002).

Bucher, M., Mair, G., Kees, F. Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers. Eur J Clin Pharmacol 57, 787-91 (2002).

Bucher, M., Hobbhahn, J., Taeger, K., Kurtz, A. Cytokine-mediated downregulation of vasopressin V_1A receptors during acute endotoxemia in rats. Am J Physiol Regul Integr Comp Physiol 282, R979-84 (2002).

Kees, F., Farber, L., Bucher, M., Mair, G., Morike, K., Grobecker, H. Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers. Br J Clin Pharmacol 52, 705-7 (2001).

Kees, F., Bucher, M., Mair, G., Grobecker, H. Determination of opipramol in human plasma by high-performance liquid chromatography with photometric detection using a cyanopropyl column. J Chromatogr B Biomed Sci Appl 753, 337-42 (2001).

Hocherl, K., Wolf, K., Castrop, H., Ittner, K. P., Bucher, M., Kees, F., Grobecker, H.F., Kurtz, A. Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT₁ receptor blockade is closely coordinated but not causally linked. Pflugers Arch 442, 821-7 (2001).

Hansen, E., Bucher, M., Jakob, W., Lemberger, P., Kees, F. Pharmacokinetics of levofloxacin during continuous veno-venous hemofiltration. Intensive Care Med 27, 371-5 (2001).

Bucher, M., Ittner, K. P., Hobbhahn, J., Taeger, K., Kurtz, A. Expression von AT₁-Rezeptoren während Endotoxämie. Anästh Intensivmed 42, 850 (2001).

Bucher, M., Ittner, K. P., Hobbhahn, J., Taeger, K. Kurtz, A. Downregulation of angiotensin II type 1 receptors during sepsis. Hypertension 38, 177-82 (2001).

Bucher, M., Hobbhahn, J., Kurtz, A. Nitric oxide-dependent down-regulation of angiotensin II type 2 receptors during experimental sepsis. Crit Care Med 29, 1750-5 (2001).

Ittner, K. P., Zimmermann, M., Bucher, M., Gessele, W., Kees, F., Kramer, B. K., Grobecker, H. F. The effect of urapidil and ramipril on hyperglycemia in streptozotocin diabetic rats. Naunyn Schmiedebergs Arch Pharmacol 361, 92-7 (2000).

Ittner, K. P., Bucher, M., Bachfischer, M., Koppenberg, J., Sefrin, P. Analgesie in der Präklinik: Darstellung ihrer Komplexität anhand von Fallbeispielen. Der Notarzt 16, 185-191 (2000).

Kramer, B. K., Bucher, M., Sandner, P., Ittner, K. P., Riegger, G. A., Ritthaler, T., Kurtz, A. Effects of hypoxia on growth factor expression in the rat kidney in vivo. Kidney Int 51, 444-7 (1997).

Bucher, M., Ittner, K. P., Zimmermann, M., Wolf, K., Hobbhahn, J., Kurtz, A. Nitric oxide synthase isoform III gene expression in rat liver is up-regulated by lipopolysaccharide and lipoteichoic acid. FEBS Lett 412, 511-4 (1997).

Bucher, M., Sandner, P., Wolf, K., Kurtz, A. Cobalt but not hypoxia stimulates PDGF gene expression in rats. Am J Physiol 271, E451-7 (1996).