Publications Prof. Dr. Frieder Kees
F. Kees, M. Bucher, F.
Schweda, H. Gschaidmeier, L. Faerber, R. Seifert. Neoimmun versus
Neoral: a bioequivalence study in healthy volunteers, and influence of
a fat-rich meal on the bioavailability of Neoimmun. N-S Arch Pharmacol. 375: 393-399 (2007).
K. Lotter, K. Höcherl, M. Bucher, F. Kees.
In vivo efficacy of telithromycin on cytokine and nitric oxide
formation in lipopolysaccharide-induced acute systemic inflammation in
mice. J Antimicrob Chemother, 58: 615-621(2006).
F. Kees, M. Bucher, F.
Schweda, H. Gschaidmeier, J. Burhenne, G. Mikus, L. Faerber.
Comparative Bioavailability of the Microemulsion Formulation of
Cyclosporine (Neoral) with a Generic Dispersion Formulation (Cicloral)
in Young Healthy Male Volunteers. Ther Drug Monit, 28: 312-320 (2006).
M. Bucher, F. K. Kees, B. Meßmann, D. Lunz, S. Rath, M. Zelenka, H. J. Schlitt, J. Hobbhahn. Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. Eur J Pharmacol, 536: 296-300 (2006).
F. Kees, M. Bucher, F.
Schweda, H. Gschaidmeier, L. Faerber, R. Seifert. Neoimmun versus
Neoral: a bioequivalence study in healthy volunteers, and influence of
a fat-rich meal on the bioavailability of Neoimmun. N-S Arch Pharmacol. (2007) in press.
Kuehnel, T. S., Schurr, C., Lotter, K., Kees, F. Penetration of telithromycin into nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis. J Antimicrob Chemother, 55:591-4 (2005).
Kees, F., Dittmar, M.,
Mair, G., Bucher, M. Cicloral versus Neoral: a bioequivalence study in
healthy volunteers, and influence of a fat-rich meal on the
bioavailability of Cicloral. Transplantation Proceedings, 36, 3234-3238 (2004).
Straub, R. H., Weidler, C., Demmel, B., Herrmann, M., Kees, F.,
Schmidt, M., Scholmerich, J., Schedel, J. Renal clearance and daily
excretion of cortisol and adrenal androgens in patients with rheumatoid
arthritis and systemic lupus erythematosus. Ann Rheum Dis. 63, 961-968 (2004).
Kees, M. G., Pongratz, G., Kees, F.,
Scholmerich, J., Straub, R. H. Via beta-adrenoceptors, stimulation of
extrasplenic sympathetic nerve fibers inhibits
lipopolysaccharide-induced TNF secretion in perfused rat spleen. J Neuroimmunol 145, 77-85 (2003).
Stratz, T., Kees, F., Muller, W. Do cytochrome enzymes influence the therapeutic effect of tropisetron in fibromyalgia? Drugs Exp Clin Res29, 91-94 (2003).
Kees, F., Jehkul, A.,
Bucher, M., Mair, G., Kiermaier, J., Grobecker, H. Bioavailability of
opipramol from a film-coated tablet, a sugar-coated tablet and an
aqueous solution in healthy volunteers. Arzneim-Forsch/Drug Res 53, 87-92 (2003).
Bucher, M., Kees, F., Taeger, K., Kurtz A. Cytokines down-regulate α1-adrenergic receptor expression during endotoxemia. Crit Care Med 31, 566-571 (2003).
Bucher, M., Mair, G., Kees, F. Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers. Eur J Clin Pharmacol 57, 787-791 (2002).
Koehler, J., Kuehnel, T., Kees, F.,
Hoecherl, K., Grobecker, H. F. Comparison of bioavailability and
metabolism with two commercial formulations of cyclosporine A in rats. Drug Metab Dispos 30, 658-62 (2002).
Straub, R. H., Pongratz ,G., Gunzler, C., Michna, A., Baier, S., Kees, F.,
Falk, W., Scholmerich, J. Immunoregulation of IL-6 secretion by
endogenous and exogenous adenosine and by exogenous purinergic agonists
in splenic tissue slices. J Neuroimmunol 125, 73-81 (2002).
Kees, F., Färber,
L., Bucher, M., Mair, G., Mörike, K., Grobecker, H.
Pharmacokinetics of therapeutic doses of tropisetron in healthy
volunteers. Br J Clin Pharmacol 52, 705-707 (2001).
Hansen, E., Bucher, M., Jakob, W., Lemberger, P., Kees, F. Pharmacokinetics of levofloxacin during continuous veno-venous hemofiltration. Int Care Med 27, 371-375 (2001).
Kees, F., Bucher, M.,
Mair, G., Grobecker, H. Determination of opipramol in human plasma by
high-peformance liquid chromatography with photometric detection using
a cyanopropyl column. J Chromatogr B 753, 337-342 (2001).
Ammon, S., Treiber, G., Kees, F., Klotz, U. Influence of age on the steady state disposition of drugs commonly used for the eradication of Helicobacter pylori. Aliment Pharmacol Ther 14, 759-66 (2000).
Okhravi, N., Guest, S., Matheson, M. M., Kees, F.,
Ficker, L. A., Tuft, S. J., Lightman, S. Assessment of the effect of
oral clarithromycin on visual outcome following presumed bacterial
endophthalmitis. Curr Eye Res 21, 691-702 (2000).
Kees, F., Holstege,
A., Ittner, K. P., Zimmermann, M., Lock, G., Scholmerich, J.,
Grobecker, H. Pharmacokinetic interaction between proton pump
inhibitors and roxithromycin in volunteers. Aliment Pharmacol Ther 14, 407-12 (2000).
Strehl, E., Kees, F. Pharmacological properties of parenteral cephalosporins: rationale for ambulatory use. Drugs 59 Suppl 3, 9-18; discussion 47-9 (2000) (review).
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