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Prof. Dr. Stefan Dove
Associate Professor
Tel: +49 941 943-4673
Fax: +49 941 943-4820
E-Mail to Stefan Dove
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Fields of Research:
- Computer-Aided Drug Research (Quantitative Structure-Activity Relationships, especially 3D-QSAR approaches, Molecular Modeling)
- Structure-activity relationships and binding models
of ligands of G-protein coupled receptors (GPCR homology models,
docking, 3D-QSAR), in particular: agonists and antagonists of
histamine-H2-, H4-, 5HT2A-, beta-adrenergic and neuropeptide Y
Y1-receptors, modeling of active receptor states
- Inhibitors of receptor tyrosine kinases (modeling and structure-based design);
grant from Deutsche Krebshilfe e.V. / Dr. Mildred Scheel Stiftung für
Krebsforschung (2001 - 2005)
- Inhibitors of bacterial hyaluronan lyases and human hyaluronidases (modeling and structure-based design)
- Substituted nucleotides as inhibitors of bacterial and human adenylyl cyclases – modeling of ligand-enzyme interactions
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Additional research interests:
- Modeling and prediction of
protein-protein interactions (e.g., of TIR domains)
- Receptor theory
Publications since 1991
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Date: 11/10
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