Recent Publications Prof. Dr. E. von Angerer
Vogel, S.,
Kaufmann, D., Pojarova, M., Muller, C., Pfaller, T., Kuhne, S., Bednarski, P.J.,
von Angerer, E. (2008): Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as
novel antimitotic agents. Bioorg. Med. Chem. 16:6436-6447
Kaufmann, D.,
Pojarova, M., Vogel, S., Liebl, R., Gastpar, R., Gross, D., Nishino, T.,
Pfaller, T., von Angerer, E. (2007) Antimitotic activities of
2-phenylindole-3-carbaldehydes in human breast cancer cells. Bioorg. Med. Chem. 15: 5122-5136
Schertl, S.,
Hartmann, R.W., Batzl-Hartmann, C., Spruss, T., Maucher, A., von Angerer, E.,
Schiller, C.D., Schneider, M.R., Gust, R., Schönenberger, H. (2007):
Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs
for the therapy of advanced or recurrent prostate cancers? Preclinical studies.
J. Cancer Res. Clin. Oncol. 133:153-67
Pojarova, M.,
Kaufmann, D., Gastpar, R., Nishino, T., Reszka, P., Bednarski, P.J., von
Angerer, E. (2007) [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the
growth of breast cancer cells by cell cycle arrest in G(2)/M phase and
apoptosis. Bioorg. Med. Chem. 15:
7368-7379
Zimmermann,
J., von Angerer, E. (2007): Estrogenic and antiestrogenic activities of
2,4-diphenylfuran-based ligands of estrogen receptors alpha and beta. J. Steroid Biochem. Mol. Biol 104:259-268
Rigden, D.J.,
Botzki, A., Nukui, M., Mewbourne, R.B., Lamani, E., Braun, S, von Angerer, E.,
Bernhardt, G., Dove, S., Buschauer, A., Jedrzejas, M.J. (2006) Design of new
benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan
lyase: structure of a complex with a 2-phenylindole. Glycobiology 16:757-765
Zimmermann,
J., Liebl, R., von Angerer, E. (2005): 2,5-Diphenylfuran-based pure
antiestrogens with selectivity for the estrogen receptor alpha. J. Steroid Biochem. Mol. Biol. 94:57-66
Bouchal, J.,
Baumforth, K.R., Svachova, M., Murray, P.G., von Angerer, E., Kolar, Z. (2005)
Microarray analysis of bicalutamide action on telomerase activity, p53 pathway
and viability of prostate carcinoma cell lines. J. Pharm. Pharmacol. 57: 83-92
Walter, G.,
Liebl, R., von Angerer, E. (2004): 2-phenylindole sulfamates: inhibitors of
steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells.
J. Steroid Biochem. Mol. Biol. 88:409-420
Walter, G.,
Liebl, R., von Angerer, E. (2004): Stilbene-based inhibitors of estrone
sulfatase with a dual mode of action in human breast cancer cells. Arch. Pharm. (Weinheim) 337: 634-44
Walter, G.,
Liebl, R., von Angerer, E. (2004): Synthesis and biological evaluation of
stilbene-based pure estrogen antagonists. Bioorg.
Med. Chem. Lett. 14:4659-63
Bouchal, J., Kolar,
Z., Mad'arova, J., Hlobilkova, A., von Angerer, E. (2002) The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in
the androgen sensitive prostatic cancer cell line LNCaP. Biochem. Pharmacol. 63:1177-1181
Golob, T.; Liebl, R.; von Angerer,
E.(2002): Sulfamoyloxy-Substituted 2-Phenylindoles: Antiestrogen-Based
Inhibitors of the Steroid Sulfatase in Human Breast Cancer Cells. Bioorg. Med. Chem. 10: 3941-3953.
von Angerer, E. (2000): Tubulin as a target for anticancer drugs. Curr. Opin. Drug Discovery Dev. 3: 575-584.
Golob, T., Biberger, C., Walter, G., von
Angerer, E. (2000): Antiestrogenic activities of 3,8-
dihydroxy-6,11-dihydrobenzo[a]carbazoles with sulfur-containing side
chains. Arch. Pharm. Pharm. Med. Chem. 333: 305-311.
von Angerer, E. (1999): New inhibitors of tubulin polymerisation. Exp.Opin.Ther.Patents, 9:1069-1081.
von Angerer, E. (1999): Structure-activity relationships. In: Handbook of Experimental Pharmacology, Vol. 135/1: Estrogens and Antiestrogens I, edited by M. Oettel, et al, pp. 81-108. Springer-Verlag, Berlin.
von Angerer, E. (1999): Antiestrogens and partial agonists. In: Handbook of Experimental Pharmacology, Vol. 135/1: Estrogens and Antiestrogens I, edited by M. Oettel, et al, pp. 55-80. Springer-Verlag, Berlin.
Newton, C.J., Schlatterer, K., Stalla,
G.K., von Angerer, E., and Wowra, B. (1998): Pharmacological
enhancement of radiosurgery response: Studies on an in vitro model
system. J. Radiosurg. 1:51-56.
Leichtl, S. and von Angerer, E. (1998): 2-Phenylbenzo[b]thiophene-based antiestrogens with mammary tumor inhibiting activity. Arch. Pharm. Pharm. Med. Chem. 331:283-289.
Gastpar, R., Goldbrunner, M., Marko, D.,
and von Angerer, E. (1998): Methoxy-substituted
3-formyl-2-phenylindoles inhibit tubulin polymerization. J.Med.Chem. 41:4965-4972.
Biberger, C. and von Angerer, E. (1998):
1-Benzyl-2-phenylindole- and 1,2-diphenylindole-based antiestrogens.
Estimation of agonist and antagonist activities in transfection assays.
J. Steroid Biochem. Mol. Biol. 64:277-285.
Goldbrunner, M., Loidl, G., Polossek,
T., Mannschreck, A., and von Angerer, E. (1997): Inhibition of tubulin
polymerization by 5,6-dihydro-indolo[2,1-a]isoquinoline derivatives. J. Med. Chem. 40:3524-3533.
Hafner, F., Holler, E., and von Angerer, E. (1996): Effect of growth factors on estrogen mediated gene expression. J. Steroid. Biochem. Mol. Biol. 58:385-393.
Biberger, C. and von Angerer, E. (1996):
2-Phenylindoles with sulfur containing side chains. Estrogen receptor
affinity, antiestrogenic potency, and antitumor activity. J. Steroid. Biochem. Mol. Biol. 58:31-43
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