Rainer Mueller, PhD
Postal Address:
Dr. Rainer Mueller
Institute of Physical and Theoretical Chemistry
University of Regensburg
93040 Regensburg
Germany
Phone:
(+49) 941 943 4521 oder 4997
Fax:
(+49) 941 943 4532
E-mail:
Rainer.Mueller@chemie.uni-regensburg.de


Short biography

Rainer Müller was born on December 22, 1968 in Schrobenhausen, Bavaria (Germany). He studied chemistry at the University of Regensburg where he graduated in February 1995. His diploma-thesis was entitled "Synthesis and physicochemical characterization of biologically degradable cationic polyelectrolytes" and was prepared at the Institute of Physical and Macromolecular Chemistry of Professor Klaus Heckmann. He obtained his PhD in February 1998 at the Laboratory of Interface Chemistry which was the follow-up institution after Professor Heckmann´s retirement. The PhD-Thesis was entitled "Synthesis of corrosion-inhibiting coupling agents for microelectronic devices".

After attaining his doctoral degree, Rainer Müller was scientific co-worker at the Laboratory of Interface Chemistry where he established a small research group focused on interface chemistry of biomaterials. Since December 2000 he is scientific assistant at the Institute of Physical and Theoretical Chemistry of the University of Regensburg of Professor Werner Kunz. He initiated several co-operations with the Departments of Trauma Surgery, Operative Dentistry, and Neurology of the University Hospital of Regensburg and other univeristy institutes which were funded by the Deutsche Forschungsgemeinschaft (DFG) or by the Bavarian State Ministry of Sciences, Research and the Arts. He finished his habilitation-thesis entitled "Chemical modification of biomaterial surfaces and scaffolds to direct biological responses in regenerative medicine" in November 2009.

Scientific interests

Colloid and Interface Chemistry, Biomaterials and Tissue Engineering

Publications

  1. R. Müller, I. Ferreira, K. Pawar, N. Weidner. Application of hydrogels to rewire the injured spinal cord. In: F. Columbus, editor. Hydrogels: Properties, preparation and applications. Nova Science Publishers, Hauppauge, NY, in press.
  2. R. Müller, A. Eidt, K.-A. Hiller, V. Katzur, S. Imazato, S. Ruhl, H. Schweikl, G. Schmalz. Influences of protein films on antimicrobial or bacteria-repellent surface coatings in a model system, using silicon wafers, Biomaterials 2009, 30, 4921-4929.
  3. P. Angele, R. Müller, D. Schumann, C. Englert, J. Zellner, B. Johnstone, J.U. Yoo, M. Nerlich, R. Kujat. Esterified hyaluronan-gelatin polymer composites with improved cell binding and chondrogenic differentiation characteristics of mesenchymal stem cells. Journal of Biomedical Materials Research A 2009, 91, 416-427.
  4. R. Bürgers, T. Cariaga, R. Müller, M. Rosentritt, U. Reischl, G. Handel, S. Hahnel. Effects of aging on surface properties and adhesion of Streptococcus mutans on various fissure sealants. Clinical Oral Investigations 2009, 13, 419-426.
  5. R. Bürgers, S. Hahnel, U. Reischl, R. Müller, M. Rosentritt, G. Handel, M. Behr. Streptococcal adhesion to various luting systems and the role of mixing errors. Acta Odontologica Scandinavica 2009, 67, 139-145.
  6. R. Müller, S. Ruhl, K.-A. Hiller, G. Schmalz, H. Schweikl. Adhesion of eukaryotic cells and Staphylococcus aureus to silicon model surfaces. Journal of Biomedical Matreials Research A 2008, 84, 817-827.
  7. R. Müller, K. Heckmann, P. Angele, R. Kujat, M. Nerlich. Improving the biocompatibility of titanium- and cobalt-based biomaterials by covalent immobilization of crosslinked collagen. In: J. Breme, R. Thull, C. J. Kirkpatrick, editors. Metallic biomaterial interfaces. Wiley-VCH, Weinheim, p. 88-92, 2007.
  8. R. Müller, G. Gröger, K.-A. Hiller, G. Schmalz, S. Ruhl. Fluorescence-based bacterial overlay method for simultaneous in situ quantification of attached bacteria. Applied Environmental Microbiology 2007, 73, 2653-2660.
  9. H. Schweikl, R. Müller, C. Englert, R. Kujat, M. Nerlich, K.-A. Hiller, G. Schmalz. Proliferation of osteoblasts and fibroblasts on model surfaces of varying roughness and surface chemistry. Journal of Material Science Materials in Medicine 2007, 18, 1895-1905.
  10. R. Müller, J. Abke, P. Angele, R. Kujat. Improving cell adhesion on titanium by covalent immobilization of collagen. Biomaterialien 2007, 8, 40-45.
  11. C. Englert, T. Blunk, R. Müller, S. Schulze von Glasser, J. Baumer, J. Fierlbeck, I. Heid, M. Nerlich, J. Hammer. Bonding of articular cartilage utilizing a combination of biochemical degradation and surface cross-linking. Arthritis Research & Therapy 2007, 9, R47.
  12. C. Englert, P. Angele, J. Fierlbeck, S. Dendorfer, T. Schubert, R. Müller, S. Lienhard, J. Zeller, M. Nerlich, C. Neumann. Konduktives Knochenersatzmaterial mit variabler Antibiotikaversetzung. Der Unfallchirurg 2007, 110, 408-413.
  13. A.A. Eljaouhari, R. Müller, M. Kellermeier, K. Heckmann, W. Kunz. New anisotropic ceramic membranes from chemically fixed dissipative structures. Langmuir 2006, 22, 11353-11359.
  14. R. Müller, K.-A. Hiller, G. Schmalz, S. Ruhl. Chemiluminescence-based detection and comparison of protein amounts adsorbed on differently modified silica surfaces. Analytical Biochemistry 2006, 359, 194-202.
  15. R. Müller, J. Abke, E. Schnell, D. Scharnweber, R. Kujat, C. Englert, D. Taheri, M. Nerlich, P. Angele. Influence of surface pretreatment of titanium- and cobalt-based biomaterials on covalent immobilization of fibrillar collagen. Biomaterials 2006, 27, 4059-4068.
  16. P. Prang, R. Müller, A.A. Eljaouhari, K. Heckmann, W. Kunz, T. Weber, C. Faber, M. Vroemen, U. Bogdahn, N. Weidner. Alginate-based anisotropic capillary hydrogels promote oriented axonal regrowth in the injured spinal cord. Biomaterials 2006, 27, 3560-3569.
  17. G. Boden, R. Holke, R. Müller. Wasserverarbeitung von nichtoxidischen Pulvern (Processing of non-oxidic powders in water). Keramische Zeitschrift 2005, 57, 220-223 (Part 1); Keramische Zeitschrift 2005, 57, 304-307 (Part 2).
  18. R. Müller, J. Abke, F. Macionczyk, U. Gbureck, Z. Ruszczak, R. Mehrl, R. Kujat, C. Englert, M. Nerlich, P. Angele. Surface engineering of stainless steel materials by tantalum coating and collagen immobilization to improve implant biocompatibility. Biomaterials 2005, 26, 6962-6972.
  19. R. Müller, K. Heckmann, G. Boden, R. Holke, M. von Ruthendorf. In situ conditioning of nanoscaled non-oxidic particles with nitrogen containing surfactants to supress oxygen uptake. In: E. Müller, C. Oestreich, editors. Handling of highly dipersed powders. Berichte aus der Verfahrenstechnik, Shaker, Aachen, pp. 87-94, 2004.
  20. R. Müller, M. Knapp, K. Heckmann, M. von Ruthendorf, G. Boden. Protecting of nanoscaled non-oxidic particles from oxygen uptake by coating with nitrogen containing surfactants. Langmuir 2004, 20, 2598-2606.
  21. P. Angele, J. Abke, R. Kujat, H. Faltermeier, D. Schumann, M. Nerlich, B. Kinner, C. Englert, Z. Ruszczak, R. Mehrl, R. Müller. Influence of different collagen species on physicochemical properties of cross-linked collagen matrices. Biomaterials 2004, 25, 2831-2841.
  22. P. Angele, R. Kujat, H. Faltermeier, D. Schumann, R. Müller, M. Nerlich. Biodegradable Hyaluronsäureester/Gelatine Kompositmatrix. Biomaterialien 2003, 4, 11-18.
  23. R. Müller, K. Heckmann, M. Habermann, T. Paul, M. Stratmann. New adhesion promoters for copper leadframes and epoxy resin. Journal of Adhesion 2000, 72, 65-83.

Abstracts (actual selection)

  1. R. Müller, K. Pawar, N. Weidner. Oriented axon outgrowth from dorsal root ganglia guided by anisotropic capillary hydrogels. World Conference on Regenerative Medicine, Leipzig, 29.-31. Oktober 2009. Regenerative Medicine 2009, 4(S2), 122-123.
  2. R. Müller, V. Katzur, S. Ruhl, G. Schmalz, K.-A. Hiller, H. Schweikl. Influence of saliva precoating on the efficacy of an antibacterial and a bacteria-repellent surface modification. Jahrestagung der Deutschen Gesellschaft für Biomaterialien, Tübingen, 8.-10. Oktober 2009.BIOmaterialien 2009, 10, 132.
  3. M. Eichler, I. Stephan, V. Katzur, R. Müller, L. Scheideler, J. Geis-Gerstorfer, F. Rupp. Conditioning layer formation on charged dendrimers. Jahrestagung der Deutschen Gesellschaft für Biomaterialien, Tübingen, 8.-10. Oktober 2009.BIOmaterialien 2009, 10, 105.
  4. V. Katzur, A. Eidt, M, Eichler, KA. Hiller, F. Rupp, G. Schmalz, S. Ruhl, R. Müller. Adhesion of Streptococcus gordonii to positively and negatively charged self-assembled monolayers. 3rd Symposium of Interface Biology of Implants, Warnemünde, 13.-15. Mai 2009.BIOmaterialien 2009, 10(S1), 76.
  5. R. Müller, K. Pawar, N. Weidner. Alginate-based anisotropic hydrogels as scaffolds for guided axon regeneration. BioStar Congress 2008, 3rd Congress on Regenerative Biology and Medicine, Stuttgart, 9.-11. Oktober 2008.Tissue Engineering A 2009, 15, 717-718..
  6. R. Müller, V. Katzur, M. Eichler, F. Rupp, J. Geis-Gerstorfer, H. Schweikl, G. Schmalz. A systematic investigation of physicochemical surface parameters influencing the adsorption of saliva proteins and the adherence of oral bacteria. Jahrestagung der Deutschen Gesellschaft für Biomaterialien, Hamburg, 20.-22. November 2008.BIOmaterialien 2008, 9, 203-204.