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Publications


Fakultät für Biologie und Vorklinische Medizin
Institute of Biochemistry, Genetics and Microbiology
Biochemistry I
Prof. Dr. Gunter Meister - Publications

2017

Quévillon Huberdeau M., Zeitler D.M., Hauptmann J., Bruckmann A., Fressigné L., Danner J., Piquet S., Strieder N., Engelmann J.C., Jannot G., Deutzmann R., Simard M.J. & Meister G. (2017)
Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.
EMBO J., 36(14): 2088-2106. Epub 2017 Jun 23.

Treiber T., Treiber N., Plessmann U., Harlander S., Daiß J.L., Eichner N., Lehmann G., Schall K., Urlaub H. & Meister G. (2017).
A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.
Mol. Cell, 66(2): 270-284.

Hauptmann J. & Meister G. (2017).
Peptide-Based Isolation of Argonaute Protein Complexes Using Ago-APP.
Methods Mol. Biol.,1580: 107-116.

Sørensen B.B., Ehrnsberger H.F., Esposito S., Pfab A., Bruckmann A., Hauptmann J., Meister G., Merkl R., Schubert T., Längst G., Melzer M., Grasser M. & Grasser K.D. (2017).
The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.
Plant Mol. Biol., 93(3): 283-298. Epub 2016 Dec 21.

Danner J., Pai B., Wankerl L. & Meister G. (2017).
Peptide-Based Inhibition of miRNA-Guided Gene Silencing.
Methods Mol. Biol., 1517: 199-210.

Szczyrba J., Jung V., Beitzinger M., Nolte E., Wach S., Hart M., Sapich S., Wiesehöfer M., Taubert H., Wennemuth G., Eichner N., Stempfl T., Wullich B., Meister G. & Grässer F.A. (2017).
Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes.
Prostate Cancer, 2017:4893921. doi: 10.1155/2017/4893921. Epub 2017 Jan 5.

Pienimaeki-Roemer A., Konovalova T., Musri M.M., Sigruener A., Boettcher A., Meister G. & Schmitz G. (2017).
Transcriptomic profiling of platelet senescence and platelet extracellular vesicles.
Transfusion, 57(1): 144-156. Epub 2016 Dec 27.


2016

Hosseini H., Obradović M.M., Hoffmann M., Harper K.L., Sosa M.S., Werner-Klein M., Nanduri L.K., Werno C., Ehrl C., Maneck M., Patwary N., Haunschild G., Gužvić M., Reimelt C., Grauvogl M., Eichner N., Weber F., Hartkopf A.D., Taran F.A., Brucker S.Y., Fehm T., Rack B., Buchholz S., Spang R., Meister G., Aguirre-Ghiso J.A. & Klein C.A. (2016).
Early dissemination seeds metastasis in breast cancer.
Nature, 540: 588-592.

Dueck A., Evers M., Henz S.R., Unger K., Eichner N., Merkl R., Berezikov E., Engelmann J.C., Weigel D., Wenzl S. & Meister G. (2016).
Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants.
BMC Genomics, 17(1): 853.

Aigner A., Buesen R., Gant T., Gooderham N., Greim H., Hackermüller J., Hubesch B., Laffont M., Marczylo E., Meister G., Petrick J.S., Rasoulpour R.J., Sauer U.G., Schmidt K., Seitz H., Slack F., Sukata T., van der Vies S.M., Verhaert J., Witwer K.W. & Poole A. (2016).
Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop.
Regul. Toxicol. Pharmacol., 82: 127-139. Epub 2016 Sep 20.

Coll-Bonfill N., Peinado V.I., Pisano M.V., Párrizas M., Blanco I., Evers M., Engelmann J.C., García-Lucio J., Tura-Ceide O., Meister G., Barberà J.A. & Musri M.M. (2016).
Correction: Slug is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype.
PLoS One. 2016 Aug 25;11(8):e0162117. doi: 10.1371/journal.pone.0162117. eCollection 2016.

Ott C.A., Linck L., Kremmer E., Meister G. & Bosserhoff A.K. (2016).
Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells.
Oncotarget. 7(38): 62292-62304.

Völler D., Linck L., Bruckmann A., Hauptmann J., Deutzmann R., Meister G. & Bosserhoff A.K. (2016).
Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.
PLoS One. 2016 11(8):e0161165. doi: 10.1371/journal.pone.0161165. eCollection 2016.

Conrad K.D., Giering F., Erfurth C., Neumann A., Fehr C., Meister G. & Niepmann M. (2016).
Correction: microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation.
PLoS One. 2016 1(7):e0160132. doi: 10.1371/journal.pone.0160132. eCollection 2016.

Coll-Bonfill N., Peinado V.I., Pisano M.V., Párrizas M., Blanco I., Evers M., Engelmann J.C., García-Lucio J., Tura-Ceide O., Meister G., Barberà J.A. & Musri M.M. (2016).
Slug is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype.
PLoS One. 2016 11(7):e0159460. doi: 10.1371/journal.pone.0159460. eCollection 2016.

Hasler D. & Meister G. (2016).
From tRNA to miRNA: RNA-folding contributes to correct entry into noncoding RNA pathways.
FEBS Lett., 590(15): 2354-2363. Epub 2016 Jul 21. Review.

Arribas-Hernández L., Marchais A., Poulsen C., Haase B., Hauptmann J., Benes V., Meister G. &  Brodersen P. (2016).
The Slicer Activity of ARGONAUTE1 is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis.
Plant Cell, 28(7): 1563-1580. Epub 2016 Jun 27.

Hasler D., Lehmann G., Murakawa Y., Klironomos F., Jakob L., Grässer F.A., Rajewsky N., Landthaler M. & Meister G. (2016).
The Lupus Autoantigen La Prevents Mis-channeling of tRNA Fragments into the Human MicroRNA Pathway.
Mol. Cell, 63(1): 110-124. Epub 2016 Jun 23.

Alles J., Menegatti J., Motsch N., Hart M., Eichner N., Reinhardt R., Meister G. & Grässer F.A. (2016).
miRNA expression profiling of Epstein-Barr virus-associated NKTL cell lines by Illumina deep sequencing.
FEBS Open Bio, 6(4): 251-263. eCollection 2016.

Kretz M., Medenbach J. & Meister G. (2016).
Special issue: RNA biology in physiology and disease.
Pflugers Arch., 468(6): 933-934. Epub 2016 May 14.

Jakob L., Treiber T., Treiber N., Gust A., Kramm K., Hansen K., Stotz M., Wankerl L., Herzog F., Hannus S., Grohmann D. & Meister G. (2016).
Structural and functional insights into fly microRNA biogenesis factor Loquacious.
RNA, 22(3): 383-396. Epub 2016 Jan 14.

Codo P., Weller M., Kaulich K., Schraivogel D., Silginer M., Reifenberger G., Meister G. & Roth P. (2016).
Control of glioma cell migration and invasiveness by GDF-15.
Oncotarget, 7(7): 7732-7746. Epub 2016 Jan 04.

De Santis R., Liepelt A., Mossanen J.C., Dueck A., Simons N., Mohs A., Trautwein C., Meister G., Marx G., Ostareck-Lederer A. & Ostareck D.H. (2016).
miR-155 targets Caspase-3 mRNA in activated macrophages.
RNA Biol., 13(1): 43-58. Epub 2015 Nov 17.


2015

Evers M., Huttner M., Dueck A., Meister G. & Engelmann J.C. (2015).
miRNA: Adaptable novel miRNA identification in plants using small RNA sequencing data.
BMC Bioinformatics, 16: 370. doi: 10.1186/s12859-015-0798-3.

Loedige I., Jakob L., Treiber T., Ray D., Stotz M., Treiber N., Hennig J., Cook K.B., Morris Q., Hughes T.R., Engelmann J.C., Krahn M.P. & Meister G. (2015).
The crystal structure of the NHL domain in complex with RNA reveals the molecular basis of Drosophila brain-tumor-mediated gene regulation.
Cell Rep., 13(6): 1206-1220. Epub 2015 Oct 29.

Hauptmann J., Schraivogel D., Bruckmann A., Manickavel S., Jakob L., Eichner N., Pfaff J., Urban M., Sprunck S., Hafner M., Tuschl T., Deutzmann R. & Meister G. (2015).
Biochemical isolation of Argonaute protein complexes by Ago-APP.
Proc. Natl. Acad. Sci. USA, 112(38): 11841-11845. Epub 2015 Sep 8.

Hünten S., Kaller M., Drepper F., Oeljeklaus S., Bonfert T., Erhard F., Dueck A., Eichner N., Friedel C.C., Meister G., Zimmer R., Warscheid B. & Hermeking H. (2015).
p53-regulated networks of protein, mRNA, miRNA and lncRNA expression revealed by integrated pSILAC and NGS analyses.
Mol. Cell. Proteomics, 14(10): 2609-2629. Epub 2015 Jul 16.

Schraivogel D., Schindler S.G., Danner J., Kremmer E., Pfaff J., Hannus S., Depping R. & Meister G. (2015).
Importin-β facillitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels.
Nucleic Acids Res., 43(15): 7447-7461. Epub 2015 Jul 13.

Liu T.T., Arango-Argoty G., Li Z., Lin Y., Kim S.W., Dueck A., Ozsolak F., Monaghan A.P., Meister G., Defranco D.B. & John B. (2015).
Noncoding RNAs that associate with YB-1 alter proliferation in prostate cancer cells.
RNA, 21(6): 1159-1172. Epub 2015 Apr 22.

2015 Knippers 02

                     

Nordheim A. & Knippers R. (Eds.), Dröge P., Meister G., Schiebel E., Vingron M. & Walter J. (2015)
Molekulare Genetik (10. Auflage)
Georg Thieme Verlag KG, Stuttgart, Germany


2014

Codo, P., Weller M., Meister G., Szabo E., Wolter M., Reifenberger G. & Roth P. (2014).
MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape.
Oncotarget, 5(17): 7651-7662.

Grassmann F., Schoenberger P.G., Brandl C., Schick T., Hasler D., Meister G., Fleckenstein M., Lindner M., Helbig H., Fauser S. & Weber B. H. (2014).
A circulating microRNA profile is associated with late-stage neovascular age-related macular degeneration.
PLoS One, 9(9):e107461. doi: 10.1371/journal.pone.0107461. eCollection 2014.

Schraivogel D. & Meister G. (2014)
Import routes and nuclear functions of Argonaute and other small RNA-binding proteins.
Trends Biochem. Sci., 39(9): 420-431. Epub 2014 Aug 14. Review.

Hauptmann J., Kater L., Löffler P., Merkl R. & Meister G. (2014)
Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage.
RNA, 20(10): 1532-1538. Epub 2014 Aug 11.

Tan G.C., Chan E., Molnar A., Sarkar R., Alexieva D., Isa I.M., Robinson S., Zhang S., Ellis P., Langford C.F., Guillot P.V., Chandrashekran A., Fisk N.M., Castellano L., Meister G., Winston R.M., Cui W., Baulcombe D. & Dibb N.J. (2014)
5´ isomiR variation is of functional and evolutionary importance.
Nucleic Acids Res., 42(14): 9424-9435. Epub 2014 Jul 23.

Kretz, M. & Meister G. (2014)
RNA Binding of PRC2: Promiscuous or well ordered?
Mol. Cell, 55(2): 157-158.

Chandran P. A., Keller A., Weinmann L., Adel Seida A., Braun M., Andreev K., Fischer B., Horn E., Schwinn S., Junker M., Houben R., Dombrowski Y., Dietl J., Finotto S., Wölfl M., Meister G. & Wischhusen J. (2014)
The TGF-β-inducible miR-23a cluster attenuates IFN-γ levels and antigen-specific cytotoxicity in human CD8+ T cells.
J. Leukoc. Biol., 96(4): 633-645. Epub 2014 Jul 16.

Hannus M., Beitzinger M., Engelmann J.C., Weickert M.T., Spang R., Hannus S. & Meister G. (2014)
siPools: highly complex but accurately defined siRNA pools eliminate off-target effects.
Nucleic Acids Res., 42(12): 8049-8061. Epub 2014 May 29.

Loedige I., Stotz M., Qamar S., Kramer K., Hennig J., Schubert T., Löffler P., Längst G., Merkl R., Urlaub H. & Meister G. (2014)
The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.
Genes Dev., 28(7): 749-764.

Dueck A. & Meister G. (2014)
Assembly and function of small RNA - Argonaute protein complexes.
Biol. Chem., 395(6): 611-629.

Dueck A., Eichner A., Sixt M. & Meister G. (2014)
A miR-155-dependent microRNA hierarchy in dentritic cell maturation and macrophage activation.
FEBS Lett., 588(4): 632-640. Epub 2014 Jan 18.


2013

Völler D., Reinders J., Meister G. & Bosserhoff A.K. (2013)
Strong reduction of AGO2 expression in melanoma and cellular consequences.
Br. J. Cancer, 109(12): 3116-3124. Epub 2013 Oct 29.

Pfaff J., Hennig J., Herzog F., Aebersold R., Sattler M., Niessing D. & Meister G. (2013)
Structural features of Argonaute-GW182 interactions.
Proc. Natl. Acad. Sci. USA, 110(40): E3770-3779. Epub 2013 Sep 16.

Pfaff J. & Meister G. (2013)
Argonaute and GW182 proteins: An effective alliance in gene silencing.
Biochem. Soc. Trans., 41(4): 855-860.

Hauptmann J. & Meister G. (2013)
Argonaute regulation: Two roads to the same destination.
Dev. Cell, 25(6): 553-554.

Meister G. (2013)
Argonaute proteins: Functional insights and emerging roles.
Nat. Rev. Genet., 14(7): 447-459. Epub 2013 Jun 04.

Hauptmann J., Dueck A., Harlander S., Pfaff J., Merkl R. & Meister G. (2013)
Turning catalytically inactive human Argonaute proteins into active slicer enzymes.
Nat. Struct. Mol. Biol., 20(7): 814-817. Epub 2013 May 12.

Chen Y., Siegel F., Kipschull S., Haas B., Fröhlich H., Meister G. & Pfeiffer A. (2013)
miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit.
Nat. Commun., 4:1769. doi:10.1038/ncomms2742.

Petri S. & Meister G. (2013)
siRNA design principles and off-target effects.
Methods Mol. Biol., 986: 59-71.

Daschkey S., Röttgers S., Giri A., Bradtke J., Teigler-Schlegel A., Meister G., Borkhardt A. & Landgraf P (2013)
MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways.
PLoS One, 8(2):e56334. Epub 2013 Feb 13.

Conrad K.D., Giering F., Erfurth C., Neumann A., Fehr C., Meister G. & Niepmann M. (2013)
MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation.
PLoS One, 8(2):e56272. Epub 2013 Feb 06.

Loedige I., Gaidatzis D., Sack R., Meister G. & Filipowicz W. (2013)
The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
Nucleic Acids Res., 41(1): 518-532. Epub 2012 Nov 03.


2012

Kwanhian W., Lenze D., Alles J., Motsch N., Barth S., Döll C., Imig J., Hummel M., Tinguely M., Trivedi P., Lulitanond V., Meister G., Renner C. & Grässer F.A. (2012)
MicroRNA-142 is mutaded in about 20% of diffuse large B-cell lymphoma.
Cancer Med., 1(2): 141-155. Epub 2012 Sep 18.

Hasler D. & Meister G. (2012)
An argonaute protein directs nuclear xrn2 function.
Mol. Cell, 48(4): 485-486.

Meinl E. & Meister G. (2012)
MicroRNAs in the CSF: Macro-advance in MS?
Neurology, 79(22): 2162-2163. Epub 2012 Oct 17.

Frohn A., Eberl H.C., Stöhr J., Glasmacher E., Rüdel S., Heissmeyer V., Mann M. & Meister G. (2012)
Dicer-dependent and -independent Argonaute2 protein interaction networks in mammalian cells.
Mol. Cell. Proteomics, 11(11): 1442-1456. Epub 2012 Aug 23.

Motsch N., Alles J., Imig J., Zhu J., Barth S., Reineke T., Tinguely M., Cogliatti S., Dueck A., Meister G., Renner C. & Grässer F.A. (2012)
MicroRNA Profiling of Epstein-Barr Virus-Associated NK/T-Cell Lymphomas by Deep Sequencing.
PLoS One, 7(8):e42193. Epub 2012 Aug 3.

Dueck A., Ziegler C., Eichner A., Berezikov E. Meister G. (2012)
MicroRNAs associated with the different human Argonaute proteins.
Nucleic Acids Res., 40(19): 9850-9862. Epub 2012 Jul 25.

Kappelmann M., Kuphal S., Meister G., Vardimon L. & Bosserhoff A.K. (2012)
MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression.
Oncogene, Epub 2012 Jul 16 [ahead of print] - PMID: 22797068

Li Z., Ender C., Meister G., Moore P.S., Chang Y. & John B. (2012)
Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs.
Nucleic Acids Res., 40(14): 6787-6799. Epub 2012 Apr 09.

Treiber T., Treiber N. & Meister G. (2012)
Regulation of microRNA biogenesis and function.
Thromb. Haemost., 107(4): 605-610. Epub 2012 Feb 08.


2011

Rüdel S., Wang Y., Lenobel R., Körner R., Hsiao H.H., Urlaub H., Patel D. & Meister G. (2011)
Phosphorylation of human Argonaute proteins affects small RNA binding.
Nucleic Acids Res., 39(6): 2330-2343. Epub 2010 Nov 10.

Imig J., Motsch N., Zhu J.Y., Barth S., Okoniewski M., Reineke T., Tinguely M., Faggioni A., Trivedi P., Meister G., Renner C. & Grässer F.A. (2011)
MicroRNA profiling in Epstein-Barr virus-associated B-cell lymphoma.
Nucleic Acids Res., 39(5): 1880-1893. Epub 2010 Nov 09.

Rna-biology Meister Cover

                    

Meister G. (2011)
RNA Biology - An Introduction.
Wiley-VCH Verlag GmbH & Co., Weinheim, Germany

Schraivogel D., Weinmann L., Beier D., Tabatabai G., Eichner A., Zhu J.Y., Anton M., Sixt M., Weller M., Beier C.P. & Meister G. (2011)
CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells.
EMBO J., 30(20): 4309-4322.

Röther S. & Meister G. (2011)
Small RNAs derived from longer non-coding RNAs.
Biochimie, 93(11): 1905-1915.

Valen E., Preker P., Andersen P.R., Zhao X., Chen Y., Ender C., Dueck A., Meister G., Sandelin A. & Jensen T.H. (2011)
Biogenic mechanisms and utilization of small RNAs from human protein-coding genes.
Nat. Struct. Mol. Biol., 18(9): 1075-1082. Epub 2011 Aug 09.

Barth S., Meister G. & Grässer F.A. (2011)
EBV-encoded miRNAs.
Biochim. Biophys. Acta, 1809: 631-640. Epub 2011 May 24.

Beitzinger M. & Meister G. (2011)
Experimental Identification of MicroRNA Targets by Immunoprecipitation of Argonaute Protein Complexes.
Methods Mol. Biol., 732: 153-167.

Stoehr J. & Meister G. (2011)
In Vitro RISC Cleavage Assay.
Methods Mol. Biol., 725: 77-90.

Meister G. (2011)
Vision: Dicer leaps into view.
Nature, 471: 308–309.

Petri S., Dueck A., Lehmann G., Putz N., Rüdel S., Kremmer E. & Meister G. (2011)
Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects.
RNA, 17(4): 737-749. Epub 2011 Mar 02.


2010

Gutierrez Aguilar A.L., Piskol R., Beitzinger M., Zhu J.Y., Kruspe D., Aszodi A., Moser M., Englert C. & Meister G. (2010)
The small RNA expression profile of the developing murine urinary and reproductive systems.
FEBS Lett., 584(21): 4426-34.

Treiber T. & Meister G. (2010)
SMADs stimulate miRNA processing.
Mol. Cell, 39: 315-316.

Zhu J.Y., Strehle M., Frohn A., Kremmer E., Höfig K.P., Meister G. & Adler H. (2010)
Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68.
J. Virol., 84(19): 10266-10275.

Dueck A. & Meister G. (2010)
MicroRNA processing without Dicer.
Genome Biol., 11(6): 123-125.

Ender C. & Meister G. (2010)
Argonaute proteins at a glance.
J. Cell Sci., 123: 1819-1823.

Dölken L., Malterer G., Erhard F., Kothe S., Friedel C.C., Suffert G., Marcinowski L., Motsch N., Barth S., Beitzinger M. Lieber D., Bailer S.M., Hoffmann R., Ruzsics Z., Kremmer E., Pfeffer S., Zimmer R., Koszinowski U.H., Grässer F., Meister G. & Haas J. (2010)
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay.
Cell Host Microbe, 7(4): 324-334.

Beitzinger M. & Meister G. (2010)
MicroRNAs: from decay to decoy.
Cell, 140: 612-614.


2009

Dueck A. & Meister G. (2009)
TRIMming microRNA function in mouse stem cells.
Nature Cell Biol., 11(12): 1392-1393.

Zhu J.Y., Pfuhl T., Motsch N., Barth S., Nicholls J., Grässer F. & Meister G. (2009)
Identification of novel Epstein-Barr Virus microRNA genes from Nasopharyngeal Carcinomas.
J. Virol., 83(7): 3333-3341.

Weinmann L., Höck J., Ivacevic T., Ohrt T., Mütze J., Schwille P., Kremmer E., Benes V., Urlaub H. & Meister G. (2009)
Importin 8 is a gene silencing factor that targets Argonaute proteins to distinct mRNAs.
Cell, 136: 496-507.


2008

2008 Mol-cell Cover 02

Ender C., Krek A., Friedländer M.R., Beitzinger M., Weinmann L., Chen W., Pfeffer S., Rajewsky N. & Meister G. (2008)
A human snoRNA with microRNA-like functions.
Mol. Cell, 32: 519-528.

Ohrt T. Mütze J., Staroske W., Weinmann L., Höck J., Crell K., Meister G. & Schwille P. (2008)
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells.
Nucleic Acids Res., 36(20): 6439-49.

Linder B., Plöttner O., Kroiss M., Hartmann E., Laggerbauer B., Meister G., Keidel E. & Fischer U. (2008)
Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP.
Hum. Mol. Genet., 17(20): 3236-3246.

Meister G. (2008)
RNA interference in the nucleus.
Science, 321: 496-497.

Rüdel S. & Meister G. (2008)
Phosphorylation of Argonaute proteins: regulating gene regulators.
Biochem. J., 413: e7-e9.

Rüdel S., Flatley A., Weinmann L., Kremmer E. & Meister G. (2008)
A multifunctional human Argonaute2-specific monoclonal antibody.
RNA, 14: 1244-1253.

Höck J. & Meister G. (2008)
The Argonaute protein family.
Genome Biol., 9: 210.

Chen P.Y., Weinmann L., Gaidatzis D., Pei Y., Zavolan M., Tuschl T. & Meister G. (2008)
Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity.
RNA, 14: 1-12.

Barth S., Pfuhl T., Mamiani A., Ehses C., Roemer K., Kremmer E., Jäker C., Höck J., Meister G. & Grässer F. (2008)
Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5.
Nucleic Acids Res., 36(2): 666-675.


2007

Höck J., Weinmann L., Ender C., Rüdel S., Kremmer E., Raabe M., Urlaub H. & Meister G. (2007)
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.
EMBO Reports, 8(11): 1052-1060.

Meister G. (2007)
miRNAs get an early start on translational silencing.
Cell, 131: 25-28.

Peters L. & Meister G. (2007)
Argonaute proteins: Mediators of RNA silencing.
Mol. Cell, 26: 611-623.

Tarasov V., Jung P., Verdoodt B., Lodygin D., Epanchintsev A., Menssen A., Meister G. & Hermeking H. (2007)
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G(1)-arrest.
Cell Cycle, 6(13): 1586-1593.

Beitzinger M., Peters L., Zhu J.Y., Kremmer E. & Meister G. (2007)
Identification of microRNA targets from isolated Argonaute protein complexes.
RNA Biol., 4(2): 76-84.


2006

Obernosterer G., Meister G., Poy M. & Kuras A. (2006)
The impact of small RNAs.
EMBO Reports. 8: 23-27.

Patel D.J., Ma J.B., Yuan Y.R., Ye K., Pei Y., Kuryavyi V., Malinina L., Meister G. & Tuschl T. (2006)
Structural Biology of RNA silencing and its functional implications.
Cold Spring Harb. Symp. Quant. Biol. 71: 81-93.

Peters L. & Meister G. (2006)
Kleine nicht-kodierende RNAs als Regulatoren der Genexpression.
BioSpektrum, 06.06, Jahrgang 12.


2005

Chen P.Y. & Meister G. (2005)
microRNA-guided posttranscriptional gene regulation.
Biol. Chem., 386: 1205-1218.

Meister G., Landthaler M., Peters L., Chen P.Y., Urlaub H., Lührmann R. & Tuschl T. (2005)
Identification of novel Argonaute-associated proteins.
Current Biology, 15: 1-7.

Azzouz T.N., Pillai R.S., Däpp C., Chari A., Meister G., Kambach C., Fischer U. & Schümperli D. (2005)
Toward an Assembly Line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.
J. Biol. Chem. 280: 34435-34440.

Winkler C., Eggert C., Gradl D., Meister G., Giegerich M., Wedlich D., Laggerbauer B. & Fischer U. (2005)
Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy.
Genes Dev., 19: 2320-2330.

Yuan Y-R., Pei Y., Ma J-B., Kuryavyi V., Zhadina M., Meister G., Chen H. Y., Dauter Z., Tuschl T. & Patel D.J. (2005)
Crystal structure of A. aeolicus Argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.
Mol. Cell, 19: 405-419.

Ma J-B., Yuan Y-R., Meister G., Pei Y., Tuschl T. & Patel D.J. (2005)
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus PIWI protein.
Nature, 434: 666-670.

Grimmler M., Martin L., Nousiainen M., Körner R., Meister G. & Fischer U. (2005)
Phosphorylation regulates the activity of the SMN-complex during assembly of spliceosomal U snRNPs.
EMBO Reports, 6(1): 70-6.


2004

Meister G., Landthaler M., Patkaniowska A., Dorsett Y., Teng G. & Thomas Tuschl (2004)
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Mol. Cell, 15: 185-197.

Meister G. & Tuschl T. (2004)
Mechanisms of gene silencing by double-stranded RNA.
Nature, 16: 343-349.

Meister G., Landthaler M., Dorsett Y. & Tuschl T. (2004)
Sequence specific inhibition of microRNA- and siRNA-induced RNA silencing.
RNA, 10(3): 544-550.

Malatesta M., Scassellati C., Meister G., Plöttner O., Bühler D., Sowa G., Martin T., Keidel E., Fischer U. & Fakan S. (2004)
Ultrastructural characterization of a nuclear domain highly enriched in Survival of Motor Neuron (SMN) protein.
Exp. Cell Res., 292: 312-321.


2003

Pillai R.S., Grimmler M., Meister G., Will C.L, Lührmann R., Fischer U. & Schümperli D. (2003)
Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.
Genes Dev., 17(18): 2321-33.

Barth S., Liss M., Voss M.D., Dobner T., Fischer U., Meister G. & Grässer F.A. (2003)
Epstein-Barr virus nuclear antigen 2 binds via its methylated arginine-glycine repeat to the survival motor neuron protein.
J. Virol., 77(8): 5008-13.


2002

Meister G., Eggert C. & Fischer U. (2002)
SMN-mediated RNP assembly: a complex story.
Trends Cell Biol., 12: 472-478.

Meister G. & Fischer U. (2002)
Assisted RNP assembly: SMN- and PRMT5-complexes cooperate in the formation of spliceosomal UsnRNPs.
EMBO J., 21: 5853-5863.

Jablonka S., Holtmann B., Meister G., Bandilla M., Rossoll W., Fischer U. & Sendtner M., (2002)
Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death.
Proc. Natl. Acad. Sci. USA, 15: 10126-31.


2001

Meister G., Eggert C., Buehler D., Brahms H., Kambach C. & Fischer U. (2001)
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln.
Current Biology, 11: 1990-1994.

Meister G., Buhler D., Pillai R., Lottspeich F. & Fischer U. (2001)
A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs.
Nat. Cell Biol., 3: 945-949.

Meister G., Hannus S., Plottner O., Baars T., Hartmann E., Fakan S., Laggerbauer B. & Fischer U. (2001)
SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.
EMBO J., 20: 2304-2314.

Meister G., Buhler D., Laggerbauer B., Zobawa M., Lottspeich F. & Fischer U. (2000)
Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins.
Hum. Mol. Genetics, 9: 1977-1986.

  1. Fakultät für Biologie und Vorklinische Medizin
  2. Faculty Research

Biochemistry I RNA-Biology

 

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