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Publikationen

2017

Gerl K, Steppan D, Fuchs M, Wagner C, Willam C, Kurtz A, Kurt B.
Activation of hypoxia signaling in stromal progenitors impairs kidney development.
Am J Pathol. 2017 Jul;187(7):1496-1511.

 

2016

Gerl K, Nolan KA, Karger C, Fuchs M, Wenger RH, Stolt CC, Willam C, Kurtz A, Kurt B. Erythropoietin production by PDGFR-β(+) cells.Pflugers Arch. 2016 Aug;468(8):1479-87. Pubmed

Kraus A, Grampp S, Goppelt-Struebe M, Schreiber R, Kunzelmann K, Peters DJ, Leipziger J, Schley G, Schödel J, Eckardt KU, Buchholz B. P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells. Purinergic Signal. 2016 Aug 26. [Epub ahead of print] Pubmed

Kraus A, Schley G, Kunzelmann K, Schreiber R, Peters DJ, Stadler R, Eckardt KU, Buchholz B. Glucose promotes secretion-dependent renal cyst growth. J Mol Med (Berl). 2016 Jan;94(1):107-17. Pubmed

 

2015

Forschbach V, Goppelt-Struebe M, Kunzelmann K, Schreiber R, Piedagnel R, Kraus A, Eckardt KU, Buchholz B. Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation. Cell Death Dis. 2015 Oct 8;6:e1899. doi: 10.1038/cddis.2015.273. Pubmed

 

2014

Buchholz B, Schley G, Faria D, Kroening S, Willam C, Schreiber R, Klanke B, Burzlaff N, Jantsch J, Kunzelmann K, Eckardt KU. Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion. J Am Soc Nephrol. 2014 Mar;25(3):465-74. Pubmed

 

2013

Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K. Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells. Kidney Int. 2014 May;85(5):1058-67. Pubmed

Kurt B, Paliege A, Willam C, Schwarzensteiner I, Schucht K, Neymeyer H, Sequeira-Lopez ML, Bachmann S, Gomez RA, Eckardt KU, Kurtz A. Deletion of von Hippel-Lindau protein converts renin-producing cells into
erythropoietin-producing cells. J Am Soc Nephrol. 2013 Feb;24(3):433-44. Pubmed

 

2011

Schley G, Klanke B, Schödel J, Forstreuter F, Shukla D, Kurtz A, Amann K, Wiesener MS, Rosen S, Eckardt KU, Maxwell PH, Willam C. Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury. J Am Soc Nephrol. 2011 Nov;22(11):2004-15. Pubmed

 

2010

Schödel J, Bohr D, Klanke B, Schley G, Schlötzer-Schrehardt U, Warnecke C, Kurtz A, Amann K, Eckardt KU, Willam C. Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells. Kidney Int. 2010 Nov;78(9):857-67. Pubmed

 

2009

Machura K, Steppan D, Neubauer B, Alenina N, Coffman TM, Facemire CS, Hilgers KF, Eckardt KU, Wagner C, Kurtz A. Developmental renin expression in mice with a defective renin-angiotensin system. Am J Physiol Renal Physiol. 2009 Nov;297(5):F1371-80. Pubmed

Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Müller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med. 2009
May;15(5):545-52. Pubmed

Schödel J, Klanke B, Weidemann A, Buchholz B, Bernhardt W, Bertog M, Amann K, Korbmacher C, Wiesener M, Warnecke C, Kurtz A, Eckardt KU, Willam C. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol. 2009 May;174(5):1663-74. Pubmed

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