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All publications of SFB960

Find all the all the publication records from June 2011 until now PubMed.

SFB Publications by Principal Investigators


Bruckmann, Astrid / Deutzmann, Rainer (Z1)

Ruther J, Hagström ÅK, Brandstetter B, Hofferberth J, Bruckmann A, Semmelmann
F, Fink M, Lowack H, Laberer S, Niehuis O, Deutzmann R, Löfstedt C, Sterner R.
Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases
accounts for sex pheromone evolution in Nasonia. Sci Rep. 2016 Oct 5;6:34697.
doi: 10.1038/srep34697. PubMed PMID: 27703264; PubMed Central PMCID: PMC5050451.

Bruckmann A, Linnemann J, Perez-Fernandez J. Purification of RNA Polymerase
I-Associated Chromatin from Yeast Cells. Methods Mol Biol. 2016;1455:213-23. doi: 10.1007/978-1-4939-3792-9_16. PubMed PMID: 27576721.

Völler D, Linck L, Bruckmann A, Hauptmann J, Deutzmann R, Meister G, Bosserhoff AK. Argonaute Family Protein Expression in Normal Tissue and Cancer Entities. PLoS One. 2016 Aug 12;11(8):e0161165. doi: 10.1371/journal.pone.0161165. PubMed PMID: 27518285; PubMed Central PMCID:
PMC4982624.

Hauptmann J., Schraivogel D., Bruckmann A., Manickavel S., Jakob L., Eichner N., Pfaff J., Urban M., Sprunck S., Hafner M., Tuschl T., Deutzmann R. & Meister G. (2015) Biochemical isolation of Argonaute protein complexes by Ago-APP. Proc. Natl. Acad. Sci. USA., 112(38):11841-5.

Dürr J, Lolas IB, Sørensen BB, Schubert V, Houben A, Melzer M, Deutzmann R, Grasser M, Grasser KD. (2014). The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Nucleic Acids Res. 42(7):4332-47.

Merkl P, Perez-Fernandez J, Pilsl M, Reiter A, Williams L, Gerber J, Böhm M, Deutzmann R, Griesenbeck J, Milkereit P, Tschochner H. (2014). Mol Cell Biol 34(20):3817-27.

Dillinger S, Garea AV, Deutzmann R, Németh A. (2014) Analysis of histone posttranslational modifications from nucleolus-associated chromatin by mass spectrometry. Methods Mol Biol 1094: 277-93.

Hamperl S, Brown CR, Garea AV, Perez-Fernandez J, Bruckmann A, Huber K, Wittner M, Babl V, Stoeckl U, Deutzmann R, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. (2013). Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae. Nucleic Acids Res. 42(1):e2.

Hierlmeier T, Merl J, Sauert M, Perez-Fernandez J, Schultz P, Bruckmann A, Hamperl S, Ohmayer U, Rachel R, Jacob A, Hergert K, Deutzmann R, Griesenbeck J, Hurt E, Milkereit P, Baßler J, Tschochner H. (2013). Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S.cerevisiae. Nucleic Acids Res 41(2):1191-210. 

Jakob S, Ohmayer U, Neueder A, Hierlmeier T, Perez-Fernandez J, Hochmuth E, Deutzmann R, Griesenbeck J, Tschochner H, Milkereit P. (2012). Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes. PLoS One. 7(3):e32552.


Dresselhaus, Thomas (B6, MGK)

Ghosh Dastidar, M., Mosiolek, M., Bleckmann, A., Dresselhaus, T., Nodine, M.D. and Maizel, A. (2016) Sensitive whole mount in situ localization of small RNAs in plants. Plant J., doi: 10.1111/tpj.13270.

Bleckmann, A., and Dresselhaus, T. (2016) Fluorescent whole-mount RNA in situ hybridization (F-WISH) in plant germ cells and the fertilized ovule. Methods.98, 66-73

Dresselhaus, T., Sprunck, S. and Wessel, G.M. (2016) Fertilization mechanisms in flowering plants. Curr. Biol. 26, R125-R139.

Hou, Y., Guo, X., Cyprys, P., Zhang, Y., Bleckmann, A., Cai, L., Huang, Q., Luo, Y., Gu, H., Dresselhaus, T., Dong, J. and Qu, L.J. (2016) Maternal ENODLs are required for pollen tube reception in Arabidopsis. Curr. Biol. 26, 2343-2350.
Müller, B., Fastner, A., Karmann, J., Mansch, V., Hoffmann, T., Schwab, W., Suter-Grotemeyer, M., Rentsch, D., Truernit, E., Ladwig, F., Bleckmann, A., Dresselhaus, T. and Hammes, U. Z. (2015) Amino acid export in developing Arabidopsis seeds depends on UmamiT facilitators. Curr. Biol. 25, 3126-3131.

Bleckmann, A., Alter, S., and Dresselhaus, T. (2014) The beginning of a seed: regulatory mechanisms of double fertilization. Front. Plant Sci. 5, 452.

Denninger, P., Bleckmann, A., Lausser, A., Vogler, F., Ott, T., Ehrhardt, D., Frommer, W.B., Sprunck, S., Dresselhaus, T.*, and Grossmann, G.* (2014) Male-female communication triggers calcium signatures during fertilization in Arabidopsis. Nature Comm. 5, 4645.

Schönberger, J., Hammes, U.Z., and Dresselhaus, T. (2012) In vivo visualization of RNA in plants cells using the lambda N22 system and a GATEWAY-compatible vector series for candidate RNAs. Plant J. 71, 173-181.


Engelmann, Julia (Z2a)

Anne Dueck, Maurits Evers, Stefan R. Henz, Katharina Unger, Norbert Eichner, Rainer Merkl, Eugene Berezikov, Julia C. Engelmann, Detlef Weigel, Stephan Wenzl and Gunter Meister (2016) Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants. BMC Genomics 17:853

Maurits Evers, Michael Huttner, Anne Dueck, Gunter Meister, Julia C Engelmann (2015) miRA: Adaptable novel miRNA identification using small RNA sequencing data. BMC Bioinformatics 16:370.

Inga Loedige, Leonhard Jakob, Thomas Treiber, Debashish Ray, Mathias Stotz, Nora Treiber, Janosch Hennig, Kate B Cook, Quaid Morris, Tim Hughes, Julia C. Engelmann, Michael Krahn, Gunter Meister (2015) The crystal structure of the NHL domain in complex with RNA reveals the molecular basis of Drosophila Brain tumor-mediated gene regulation. Cell Reports 13 (6): 1206-1220.

de Jel MM, Engelmann JC, Kunz M, Schiffner S, Kuphal S, Bosserhoff AK (2014): Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. Pigment Cell & Melanoma Research 27 (4): 678-680.

Engelmann JC and Spang R (2012): A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions. PLoS One 7(7): e40634.

Publications within the broader context of the SFB960 (analyses of high-throughput datasets, including sequence analyses)

Hannus M, Beitzinger M, Engelmann JC, Weickert MT, Spang R, Hannus S, Meister G (2014): siPools: highly complex but accurately defined siRNA pools eliminate off-target effects. Nucleic Acids Research 42 (12): 8049-8061.

Aryee MJ, Liu W, Engelmann JC, Nuhn P, Gurel M, Haffner MC, Esopi D, Irizarry RA, Getzenberg RH, Nelson WG, Luo J, Xu J, Isaacs WB, Bova GS, Yegnasubramanian S (2013): DNA Methylation Alterations Exhibit Intraindividual Stability and Interindividual Heterogeneity in Prostate Cancer Metastases. Science Translational Medicine 5:169. 169ra10.

Dolnik A*, Engelmann JC*, Scharfenberger-Schmeer M, Mauch J, Kelkenberg-Schade S, Haldemann B, Fries T, Kroenke J, Kuehn MWM, Paschka P, Kayser S, Wolf S, Gaidzik VI, Schlenk RF, Ruecker FG, Doehner H, Lottaz C, Doehner K, Bullinger L (2012): Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin-remodeling and splicing. Blood 120:18. e83-92.
*contributed equally

Vogelmann K, Drechsel G, Bergler J, Subert C, Philippar K, Soll J, Engelmann JC, Engelsdorf T, Voll LM, Hoth S (2012): Early senescence and cell death in Arabidopsis saul1 mutants involves the PAD4-dependent salicylic acid pathway. Plant Physiology 159:4.1477-87.

Lee CW, Efetova M, Engelmann JC, Kramell R, Wasternack C, Ludwig-Müller J, Hedrich R, Deeken R (2009): Agrobacterium tumefaciens promotes tumor induction by modulating pathogen-defense in Arabidopsis thaliana. Plant Cell 21:9.2948-2962.

 


Grasser, Klaus (A6)

The zinc-finger protein SPT4 interacts with SPT5L/KTF1 and modulates transcriptional silencing in Arabidopsis. Köllen K, Dietz L, Bies-Etheve N, Lagrange T, Grasser M, Grasser KD. FEBS Lett. 2015 Oct 24;589(21):3254-7. doi: 10.1016/j.febslet.2015.09.017.

Transcript elongation factors: shaping transcriptomes after transcript initiation. Van Lijsebettens M, Grasser KD. Trends Plant Sci. 2014 Nov;19(11):717-26. doi: 10.1016/j.tplants.2014.07.002.

Elongator and SPT4/SPT5 complexes as proxy to study RNA polymerase II transcript elongation control of plant development. Van Lijsebettens M, Dürr J, Woloszynska M, Grasser KD. Proteomics. 2014 Oct;14(19):2109-14. doi: 10.1002/pmic.201400024.

The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Dürr J, Lolas IB, Sørensen BB, Schubert V, Houben A, Melzer M, Deutzmann R, Grasser M, Grasser KD. Nucleic Acids Res. 2014 Apr;42(7):4332-47. doi: 10.1093/nar/gku096.

Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. Kammel C, Thomaier M, Sørensen BB, Schubert T, Längst G, Grasser M, Grasser KD. PLoS One. 2013;8(3):e60644. doi: 10.1371/journal.pone.0060644.


Griesenbeck, Joachim (A5, A1, B1)

Structure of the initiation-competent RNA polymerase I and its implication for transcription. Pilsl M, Crucifix C, Papai G, Krupp F, Steinbauer R, Griesenbeck J, Milkereit P, Tschochner H, Schultz P., Nat Commun. 2016 Jul 15;7:12126. doi: 10.1038/ncomms12126. PMID: 27418187

Analysis of S. cerevisiae RNA Polymerase I Transcription In Vitro. Pilsl M, Merkl PE, Milkereit P, Griesenbeck J, Tschochner H., Methods Mol Biol. 2016;1455:99-108. doi: 10.1007/978-1-4939-3792-9_8.PMID: 27576713

Studies on the Coordination of Ribosomal Protein Assembly Events Involved in Processing and Stabilization of Yeast Early Large Ribosomal Subunit Precursors. Ohmayer U, Gil-Hernández Á, Sauert M, Martín-Marcos P, Tamame M, Tschochner H, Griesenbeck J, Milkereit P. PLoS One. 2015 Dec 7;10(12):e0143768. doi: 10.1371/journal.pone.0143768. eCollection 2015.

Chromatin Endogenous Cleavage (ChEC) as a Method to Quantify Protein Interaction with Genomic DNA in Saccharomyces cerevisiae. Babl V, Stöckl U, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2015;1334:219-32. doi: 10.1007/978-1-4939-2877-4_14.

Chromatin structure analysis of single gene molecules by psoralen cross-linking and electron microscopy. Brown CR, Eskin JA, Hamperl S, Griesenbeck J, Jurica MS, Boeger H. Methods Mol Biol. 2015;1228:93-121. doi: 10.1007/978-1-4939-1680-1_9.

Binding of the termination factor Nsi1 to its cognate DNA site is sufficient to terminate RNA polymerase I transcription in vitro and to induce termination in vivo. Merkl P, Perez-Fernandez J, Pilsl M, Reiter A, Williams L, Gerber J, Böhm M, Deutzmann R, Griesenbeck J, Milkereit P, Tschochner H. Mol Cell Biol. 2014 Oct;34(20):3817-27. doi: 10.1128/MCB.00395-14. Epub 2014 Aug 4.

Purification of specific chromatin domains from single-copy gene loci in Saccharomyces cerevisiae. Hamperl S, Brown CR, Perez-Fernandez J, Huber K, Wittner M, Babl V, Stöckl U, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2014;1094:329-41. doi: 10.1007/978-1-62703-706-8_26.

Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae. Hamperl S, Brown CR, Garea AV, Perez-Fernandez J, Bruckmann A, Huber K, Wittner M, Babl V, Stoeckl U, Deutzmann R, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Nucleic Acids Res. 2014 Jan;42(1):e2. doi: 10.1093/nar/gkt891. Epub 2013 Oct 7.

UV light-induced DNA lesions cause dissociation of yeast RNA polymerases-I and establishment of a specialized chromatin structure at rRNA genes. Tremblay M, Charton R, Wittner M, Levasseur G, Griesenbeck J, Conconi A. Nucleic Acids Res. 2014 Jan;42(1):380-95. doi: 10.1093/nar/gkt871. Epub 2013 Oct 4.

Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. Ohmayer U, Gamalinda M, Sauert M, Ossowski J, Pöll G, Linnemann J, Hierlmeier T, Perez-Fernandez J, Kumcuoglu B, Leger-Silvestre I, Faubladier M, Griesenbeck J, Woolford J, Tschochner H, Milkereit P. PLoS One. 2013 Jul 10;8(7):e68412. doi: 10.1371/journal.pone.0068412. Print 2013.

Chromatin states at ribosomal DNA loci. Hamperl S, Wittner M, Babl V, Perez-Fernandez J, Tschochner H, Griesenbeck J. Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):405-17. doi: 10.1016/j.bbagrm.2012.12.007. Epub 2013 Jan 3. Review.

Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae. Hierlmeier T, Merl J, Sauert M, Perez-Fernandez J, Schultz P, Bruckmann A, Hamperl S, Ohmayer U, Rachel R, Jacob A, Hergert K, Deutzmann R, Griesenbeck J, Hurt E, Milkereit P, Baßler J, Tschochner H. Nucleic Acids Res. 2013 Jan;41(2):1191-210. doi: 10.1093/nar/gks1056. Epub 2012 Dec 2.

RNA polymerase I termination: Where is the end? Németh A, Perez-Fernandez J, Merkl P, Hamperl S, Gerber J, Griesenbeck J, Tschochner H. Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):306-17. doi: 10.1016/j.bbagrm.2012.10.007. Epub 2012 Oct 23. Review.

Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins. Ohmayer U, Perez-Fernandez J, Hierlmeier T, Pöll G, Williams L, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(8):e42449. doi: 10.1371/journal.pone.0042449. Epub 2012 Aug 2.

The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. Reiter A, Hamperl S, Seitz H, Merkl P, Perez-Fernandez J, Williams L, Gerber J, Németh A, Léger I, Gadal O, Milkereit P, Griesenbeck J, Tschochner H. EMBO J. 2012 Aug 15;31(16):3480-93. doi: 10.1038/emboj.2012.185. Epub 2012 Jul 17.

Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes. Jakob S, Ohmayer U, Neueder A, Hierlmeier T, Perez-Fernandez J, Hochmuth E, Deutzmann R, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(3):e32552. doi: 10.1371/journal.pone.0032552. Epub 2012 Mar 14.

Chromatin endogenous cleavage and psoralen crosslinking assays to analyze rRNA gene chromatin in vivo. Griesenbeck J, Wittner M, Charton R, Conconi A. Methods Mol Biol. 2012;809:291-301. doi: 10.1007/978-1-61779-376-9_20.

Selective removal of promoter nucleosomes by the RSC chromatin-remodeling complex. Lorch Y, Griesenbeck J, Boeger H, Maier-Davis B, Kornberg RD. Nat Struct Mol Biol. 2011 Jul 3;18(8):881-5. doi: 10.1038/nsmb.2072.


Grohmann, Dina (A7)

Sheppard C., Blombach F., Belsom A., Schulz S., Daviter T., Smollett K., Mahieu E., Erdmann S., Tinnefeld P., Garrett R., Grohmann D., Rappsilber J. and Werner F. (2016). Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP. Nature Communications (in press)

Nickels P.C., Wünsch B., Holzmeister P., Bae W., Kneer L.M., Grohmann D., Tinnefeld P. and Liedl T. (2016), Molecular Force Spectroscopy with a DNA Origami-Based Nanoscopic Force Clamp. Science. 354(6310):305-307.

Blombach B., Smollett K.L., Grohmann D. and Werner F. (2016). Molecular Mechanisms of Transcription Initiation – structure, function and evolution of TFE/TFIIE-like factors and open complex formation. Journal of Molecular Biology. 428(12):2592-606.

Schulz S., Gietl A., Smollett K., Tinnefeld P., Werner F. and Grohmann D. (2016). TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle. Proceedings of the National Academy of Sciences U.S.A. 112(13): E1816-25

Jakob L., Treiber T., Treiber N., Gust A., Kramm K., Hansen K., Stotz M., Wankerl L., Herzog F., Hannus S., Grohmann D. and Meister G. (2016). Structural and functional insights into the fly microRNA biogenesis factor Loquacious. RNA. 22(3): 383-96.

Schulz S., Kramm K., Werner F., Grohmann D. (2015). A fluorescently labeled recombinant RNAP system to probe archaeal transcription initiation. Methods (epub, ahead of print)

Willkomm S., Zander A., Gust A., Grohmann D. (2015). A prokaryotic twist on Argonaute action. Life. 5 (1), 538-553.

Nagy J., Grohmann D., Cheung A.C.M., Schulz S., Smollett K., Werner F. & Michaelis J. (2015): Complete architecture of the archaeal RNA polymerase open complex from single-molecule FRET and NPS, Nature Communications, 6:6161

Gietl A., Holzmeister P., Blombach F., Schulz S., Voithenberg L.V.v., Lamb D., Werner F., Tinnefeld P., Grohmann D. (2014) Single-molecule analysis reveals diverse pathways during early steps in transcription initiation. Nucleic Acids Research. 42(10):6219-31.

Zander A., Holzmeister P., Klose D., Tinnefeld P. and Grohmann D. (2014). Single-molecule FRET supports the two-state model of Argonaute action. RNA Biology 11(1):45-56.

Grohmann D.  and Werner F. (2011) Recent advances in the understanding of archaeal transcription. Curr Opin Microbiol.

Grohmann D., Nagy J., Chakraborty A., Klose D., Fielden D., Ebright R.H., Michaelis J., Werner F.* (2011). The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation. Molecular Cell, 43:263-74.

Werner F. and Grohmann D. (2011) Evolution of multisubunit RNA polymerases in the three domains of life. Nature Rev Microbiol.9:85-98.


Kretz, Markus (B9)

Lopez-Pajares V., Qu, K., Zhang, J., Webster, D.E., Barajas, B.C., Siprashvili, Z., Zarnegar, B.J., Boxer, L.D., Rios, E.J., Tao, S., Kretz, M., Khavari, P.A. (2015). A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation. Dev Cell, 32(6): 693-706.

Kretz M. (2013). TINCR, staufen1, and cellular differentiation. RNA Biol, 10(10): 1597-601.

Hombach S., Kretz M. (2013). The non-coding skin: Exploring the roles of long non-coding RNAs in epidermal homeostasis and disease. Bioessays, 35(12): 1093-100.

Kretz M., Siprashvili Z.*, Chu C.*, Webster D.E.*, Zehnder A., Lee C.S., Flockhart R.J., Chow J., Johnston D., Groff A.F., Kim G.E., Raj A., Rinn J.L., Chang H.Y., Khavari P.A. (2013). Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature, 493(7431):231-5.

Flockhart R.J., Webster D.E., Qu K., Mascarenhas N., Kovalski J., Kretz M., Khavari P.A. (2012). BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration. Genome Res, 2012 Jun;22(6):1006-14.

Kretz M.*, Webster D.E.*, Flockhart R.J., Lee C.S., Zehnder A., Lopez-Pajares V., Qu K., Zheng G. X. Y., Chow J., Kim G. E.,  Rinn J.L., Chang H.Y., Siprashvili Z., Khavari P.A. (2012). Suppression of progenitor differentiation requires the long non-coding RNA ANCR. Genes Dev, 26(4):338-43.

Siprashvili Z., Webster D.E., Kretz M., Johnston D., Rinn J.L., Chang H.Y., Khavari P.A. (2012). Identification of proteins binding coding and non-coding human RNAs using protein microarrays. BMC Genomics, 13(1):633.


Längst, Gernot (A4, B2)

Diermeier S, Kolovos P, Heizinger L, Schwartz U, Georgomanolis T, Zirkel A, Wedemann G, Grosveld F, Knoch T, Merkl R, Cook PR, Längst* G, Papantonis* A. (2015) TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning. Genome Biology – accepted

Krinner S, Heitzer AP, Diermeier SD, Obermeier I, Längst G*, Wagner* R. (2014) CpG domains downstream of TSSs promote high levels of gene expression. Nucleic Acids Res. 2014 Apr;42(6):3551-64.

Diermeier SD, Längst G. (2014) Deep sequencing of small chromatin-associated RNA: bioinformatic analysis. Methods Mol Biol. 2014;1094:355-9.

Diermeier SD, Schubert T, Längst G. (2014) Deep sequencing of small chromatin-associated RNA: isolation and library preparation. Methods Mol Biol. 2014;1094:343-53.

Manelyte L, Strohner R, Gross T, Längst G. (2014) Chromatin targeting signals, nucleosome positioning mechanism and non-coding RNA-mediated regulation of the chromatin remodeling complex NoRC. PLoS Genet. 2014 Mar 20;10(3):e1004157.

Diermeier SD, Németh A, Rehli M, Grummt I, Längst G. (2013) Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet. 2013;9(9):e1003786.

Zillner K, Filarsky M, Rachow K, Weinberger M, Längst* G, Németh* A. (2013) Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Res. 2013 May 1;41(10):5251-62.

Pham TH, Minderjahn J, Schmidl C, Hoffmeister H, Schmidhofer S, Chen W, Längst G, Benner C, Rehli M. (2013) Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1. Nucleic Acids Res. 2013 Jul;41(13):6391-402.

Schubert, T. and Längst, G. (2013) Changes in higher order structures of chromatin by RNP complexes. RNA Biol. 10(2)

Schubert T., Pusch M., Diermeier S., Benes V., Kremmer E.,  Imhof A. and Längst G. (2012) Df31 protein and snoRNAs maintain accessible higher order structures of chromatin. Mol Cell. Nov 9;48(3):434-44

Zillner K., Jerabek-Willemsen M., Duhr S., Braun D., Längst G., and Baaske P. (2012) Microscale thermophoresis as a sensitive method to quantify protein: nucleic Acid interactions in solution. Methods Mol Biol. 815:241-52.

Hochstatter J., Hölzel M., Rohrmoser M., Schermelleh L., Leonhardt H., Keough R., Gonda T., Imhof A., Eick D., Längst* G., and Németh* A. (2012) Myb-binding Protein 1a (Mybbp1a) Regulates Levels and Processing of Pre-ribosomal RNA. J Biol Chem. Jul 13;287(29):24365-77

Németh A, Längst G. (2011) Genome organization in and around the nucleolus. Trends Genet. 27(4), 149-156

Felle M, Hoffmeister H, Rothammer J, Fuchs A, Exler JH, Längst G (2011) Nucleosomes protect DNA from DNA methylation in vivo and in vitro. Nucleic Acids Res. 39(16):6956-69.

 


Medenbach, Jan (B11)

Beckmann BM, Castello A, Medenbach J. The expanding universe of
ribonucleoproteins: of novel RNA-binding proteins and unconventional
interactions. Pflugers Arch. 2016 Jun;468(6):1029-40. doi:
10.1007/s00424-016-1819-4. Epub 2016 May 10. Review. PubMed PMID: 27165283; PubMed Central PMCID: PMC4893068.

Medenbach, J., Seiler, M., and Hentze, MW.: Translational control via protein-regulated upstream open reading frames. Cell, 2011, 145(6):902-13.


Meister, Gunter (B3, B4)

Anne Dueck, Maurits Evers, Stefan R. Henz, Katharina Unger, Norbert Eichner, Rainer Merkl, Eugene Berezikov, Julia C. Engelmann, Detlef Weigel, Stephan Wenzl and Gunter Meister (2016) Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants. BMC Genomics 17:853
Hauptmann J., Schraivogel D., Bruckmann A., Manickavel S., Jakob L., Eichner N., Pfaff J., Urban M., Sprunck S., Hafner M., Tuschl T., Deutzmann R. & Meister G. (2015) Biochemical isolation of Argonaute protein complexes by Ago-APP. Proc. Natl. Acad. Sci. USA., 112(38):11841-5.

Schraivogel D., Schindler S.G., Danner J., Kremmer E., Pfaff J., Hannus S., Depping R. & Meister G. (2015). Importin-β facillitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015 Jul 13. pii: gvk705. [Epub ahead of print] PMID: 26170235.

Tan G.C., Chan E., Molnar A., Sarkar R., Alexieva D., Isa I.M., Robinson S., Zhang S., Ellis P., Langford C.F., Guillot P.V., Chandrashekran A., Fisk N.M., Castellano L., Meister G., Winston R.M., Cui W., Baulcombe D. & Dibb N.J. (2014)
 5´ isomiR variation is of functional and evolutionary importance. Nucleic Acids Res., 42(14): 9424-9435.

Schraivogel D. & Meister G. (2014) Import routes and nuclear functions of Argonaute and other small RNA-silencing proteins. Trends Biochem Sci. 39(9):420-31.

Hauptmann J., Kater L., Löffler P., Merkl R. & Meister G. (2014) Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage. RNA, 20(10):1532-8.

Völler D., Reinders J., Meister G. & Bosserhoff A.K. (2013) Strong reduction of AGO2 expression in melanoma and cellular consequences. Br. J. Cancer, 109(12): 3116-3124.

Pfaff J., Hennig J., Herzog F., Aebersold R., Sattler M., Niessing D. & Meister G. (2013) Structural features of GW – Argonaute protein interactions. Proc. Natl. Acad. Sci. USA., 110(40):E3770-9.

Hauptmann J., Dueck A., Harlander S., Pfaff J., Merkl R. & Meister G. (2013) Turning catalytically inactive human Argonaute proteins into active slicer enzymes. Nat. Struct. Mol. Biol., 20(7):814-817.

Frohn A., Eberl H.C., Stöhr J., Glasmacher E., Rüdel S., Heismeyer V., Mann M. & Meister G. (2012) Dicer-dependent and -independent Argonaute2 protein interaction networks in mammalian cells. Molecular and Cellular Proteomics, 11(11):1442-56.

Dueck A., Ziegler C., Eichner A., Berezikov E. & Meister G. (2012) microRNAs associated with the different human Argonaute proteins. Nucleic Acids Res., 40(19):9850-62.

Li Z., Ender C., Meister G., Moore P.S., Chang Y. & John B. (2012) Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res., 40(14):6787-99.

Valen E., Preker P., Andersen P.R., Zhao X., Chen Y., Ender C., Dueck A., Meister G., Sandelin A. & Jensen T.H. (2011) Biogenic mechanisms and utilization of small RNAs from human protein-coding genes. Nat. Struct. Mol. Biol., 18(9):1075-82.

Rüdel S., Wang Y., Lenobel R., Körner R., Hsiao H., Urlaub H., Patel D. & Meister G. (2011) Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Research, 39(6):2330-2343.

 


Merkl, Rainer (Z2b)

Filarsky M, Zillner K, Araya I, Villar-Garea A, Merkl R, Längst G, Németh A., The extended AT-hook is a novel RNA binding motif. RNA Biol. 2015 Jul 9:0. [Epub ahead of print] PubMed PMID: 26156556.

Woriedh M, Merkl R, Dresselhaus T. Maize EMBRYO SAC family peptides interact differentially with pollen tubes and fungal cells. J Exp Bot. 2015 Jun 12. pii: erv268. [Epub ahead of print] PubMed PMID: 26071527.

Diermeier S, Kolovos P, Heizinger L, Schwartz U, Georgomanolis T, Zirkel A,
Wedemann G, Grosveld F, Knoch TA, Merkl R, Cook PR, Längst G, Papantonis A. TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning. Genome Biol. 2014 Dec 3;15(12):536. doi:10.1186/s13059-014-0536-6. PubMed PMID: 25608606; PubMed Central PMCID: PMC4268828.

Hauptmann J, Kater L, Löffler P, Merkl R, Meister G. Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage. RNA. 2014 Oct;20(10):1532-8. doi: 10.1261/rna.045203.114. Epub 2014 Aug 11. PubMed PMID: 25114291; PubMed Central PMCID: PMC4174435.

Loedige I, Stotz M, Qamar S, Kramer K, Hennig J, Schubert T, Löffler P, Längst
G, Merkl R, Urlaub H, Meister G. The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Genes Dev. 2014 Apr 1;28(7):749-64. doi: 10.1101/gad.236513.113. PubMed PMID: 24696456; PubMed Central PMCID: PMC4015489.

Hauptmann J, Dueck A, Harlander S, Pfaff J, Merkl R, Meister G. Turning
catalytically inactive human Argonaute proteins into active slicer enzymes. Nat
Struct Mol Biol. 2013 Jul;20(7):814-7. doi: 10.1038/nsmb.2577. Epub 2013 May 12. PubMed PMID: 23665583.


Milkereit, Philipp (B1, A1, A5)

Structure of the initiation-competent RNA polymerase I and its implication for transcription. Pilsl M, Crucifix C, Papai G, Krupp F, Steinbauer R, Griesenbeck J, Milkereit P, Tschochner H, Schultz P., Nat Commun. 2016 Jul 15;7:12126. doi: 10.1038/ncomms12126. PMID: 27418187

Analysis of S. cerevisiae RNA Polymerase I Transcription In Vitro. Pilsl M, Merkl PE, Milkereit P, Griesenbeck J, Tschochner H., Methods Mol Biol. 2016;1455:99-108. doi: 10.1007/978-1-4939-3792-9_8.PMID: 27576713

Studies on the Coordination of Ribosomal Protein Assembly Events Involved in Processing and Stabilization of Yeast Early Large Ribosomal Subunit Precursors. Ohmayer U, Gil-Hernández Á, Sauert M, Martín-Marcos P, Tamame M, Tschochner H, Griesenbeck J, Milkereit P. PLoS One. 2015 Dec 7;10(12):e0143768. doi: 10.1371/journal.pone.0143768. eCollection 2015.

Chromatin Endogenous Cleavage (ChEC) as a Method to Quantify Protein Interaction with Genomic DNA in Saccharomyces cerevisiae. Babl V, Stöckl U, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2015;1334:219-32. doi: 10.1007/978-1-4939-2877-4_14.

In vitro reconstitution of yeast tUTP/UTP A and UTP B subcomplexes provides new insights into their modular architecture. Pöll G, Li S, Ohmayer U, Hierlmeier T, Milkereit P, Perez-Fernandez J. PLoS One. 2014 Dec 12;9(12):e114898. doi: 10.1371/journal.pone.0114898. eCollection 2014.

Binding of the termination factor Nsi1 to its cognate DNA site is sufficient to terminate RNA polymerase I transcription in vitro and to induce termination in vivo. Merkl P, Perez-Fernandez J, Pilsl M, Reiter A, Williams L, Gerber J, Böhm M, Deutzmann R, Griesenbeck J, Milkereit P, Tschochner H. Mol Cell Biol. 2014 Oct;34(20):3817-27. doi: 10.1128/MCB.00395-14. Epub 2014 Aug 4.

Purification of specific chromatin domains from single-copy gene loci in Saccharomyces cerevisiae. Hamperl S, Brown CR, Perez-Fernandez J, Huber K, Wittner M, Babl V, Stöckl U, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2014;1094:329-41. doi: 10.1007/978-1-62703-706-8_26.

Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae. Hamperl S, Brown CR, Garea AV, Perez-Fernandez J, Bruckmann A, Huber K, Wittner M, Babl V, Stoeckl U, Deutzmann R, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Nucleic Acids Res. 2014 Jan;42(1):e2. doi: 10.1093/nar/gkt891. Epub 2013 Oct 7.

Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. Ohmayer U, Gamalinda M, Sauert M, Ossowski J, Pöll G, Linnemann J, Hierlmeier T, Perez-Fernandez J, Kumcuoglu B, Leger-Silvestre I, Faubladier M, Griesenbeck J, Woolford J, Tschochner H, Milkereit P. PLoS One. 2013 Jul 10;8(7):e68412. doi: 10.1371/journal.pone.0068412. Print 2013.

Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae. Hierlmeier T, Merl J, Sauert M, Perez-Fernandez J, Schultz P, Bruckmann A, Hamperl S, Ohmayer U, Rachel R, Jacob A, Hergert K, Deutzmann R, Griesenbeck J, Hurt E, Milkereit P, Baßler J, Tschochner H. Nucleic Acids Res. 2013 Jan;41(2):1191-210. doi: 10.1093/nar/gks1056. Epub 2012 Dec 2.

Ribosomal proteins L7 and L8 function in concert with six A assembly factors to propagate assembly of domains I and II of 25S rRNA in yeast 60S ribosomal subunits. Jakovljevic J, Ohmayer U, Gamalinda M, Talkish J, Alexander L, Linnemann J, Milkereit P, Woolford JL Jr. RNA. 2012 Oct;18(10):1805-22. doi: 10.1261/rna.032540.112. Epub 2012 Aug 14.

Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins. Ohmayer U, Perez-Fernandez J, Hierlmeier T, Pöll G, Williams L, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(8):e42449. doi: 10.1371/journal.pone.0042449. Epub 2012 Aug 2.

The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. Reiter A, Hamperl S, Seitz H, Merkl P, Perez-Fernandez J, Williams L, Gerber J, Németh A, Léger I, Gadal O, Milkereit P, Griesenbeck J, Tschochner H. EMBO J. 2012 Aug 15;31(16):3480-93. doi: 10.1038/emboj.2012.185. Epub 2012 Jul 17.

Small ribosomal protein RPS0 stimulates translation initiation by mediating 40S-binding of eIF3 via its direct contact with the eIF3a/TIF32 subunit. Kouba T, Dányi I, Gunišová S, Munzarová V, Vlčková V, Cuchalová L, Neueder A, Milkereit P, Valášek LS. PLoS One. 2012;7(7):e40464. doi: 10.1371/journal.pone.0040464. Epub 2012 Jul 5.

Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes. Jakob S, Ohmayer U, Neueder A, Hierlmeier T, Perez-Fernandez J, Hochmuth E, Deutzmann R, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(3):e32552. doi: 10.1371/journal.pone.0032552. Epub 2012 Mar 14.


Seufert, Wolfgang (B10)

Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. Panvert M, Dubiez E, Arnold L, Perez J, Mechulam Y, Seufert W, Schmitt E.Structure. 2015 Jul 21. pii: S0969-2126(15)00267-1. doi: 10.1016/j.str.2015.06.014. [Epub ahead of print]

Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2).Perzlmaier AF, Richter F, Seufert W. J Biol Chem. 2013 Jul 26;288(30):21537-46. doi: 10.1074/jbc.M113.472290. Epub 2013 Jun 17

 


Sprunck, Stefanie (B5)

Hauptmann J., Schraivogel D., Bruckmann A., Manickavel S., Jakob L., Eichner N., Pfaff J., Urban M., Sprunck S., Hafner M., Tuschl T., Deutzmann R., Meister G. (2015) Biochemical isolation of Argonaute protein complexes by Ago-APP. Proc Natl Acad Sci U S A 112(38):11841-5.

Völz, R., von Lyncker, L., Baumann, N., Dresselhaus, T., Sprunck, S. and Groß-Hardt, R. (2012). LACHESIS-dependent egg-cell signaling regulates the development of female gametophytic cells. Development 139, 498-502.

Sprunck, S., Rademacher, S., Vogler, S., Gheyselinck, J., Grossniklaus, U. and Dresselhaus, T. (2012). Egg cell–secreted EC1 triggers sperm cell activation during double fertilization. Science 338, 1093-1097.


Tschochner, Herbert (A1, A5, B1)

Structure of the initiation-competent RNA polymerase I and its implication for transcription. Pilsl M, Crucifix C, Papai G, Krupp F, Steinbauer R, Griesenbeck J, Milkereit P, Tschochner H, Schultz P., Nat Commun. 2016 Jul 15;7:12126. doi: 10.1038/ncomms12126. PMID: 27418187

Analysis of S. cerevisiae RNA Polymerase I Transcription In Vitro. Pilsl M, Merkl PE, Milkereit P, Griesenbeck J, Tschochner H., Methods Mol Biol. 2016;1455:99-108. doi: 10.1007/978-1-4939-3792-9_8.PMID: 27576713

Studies on the Coordination of Ribosomal Protein Assembly Events Involved in Processing and Stabilization of Yeast Early Large Ribosomal Subunit Precursors. Ohmayer U, Gil-Hernández Á, Sauert M, Martín-Marcos P, Tamame M, Tschochner H, Griesenbeck J, Milkereit P. PLoS One. 2015 Dec 7;10(12):e0143768. doi: 10.1371/journal.pone.0143768. eCollection 2015.

Chromatin Endogenous Cleavage (ChEC) as a Method to Quantify Protein Interaction with Genomic DNA in Saccharomyces cerevisiae. Babl V, Stöckl U, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2015;1334:219-32. doi: 10.1007/978-1-4939-2877-4_14.

Binding of the termination factor Nsi1 to its cognate DNA site is sufficient to terminate RNA polymerase I transcription in vitro and to induce termination in vivo. Merkl P, Perez-Fernandez J, Pilsl M, Reiter A, Williams L, Gerber J, Böhm M, Deutzmann R, Griesenbeck J, Milkereit P, Tschochner H. Mol Cell Biol. 2014 Oct;34(20):3817-27. doi: 10.1128/MCB.00395-14. Epub 2014 Aug 4.

Purification of specific chromatin domains from single-copy gene loci in Saccharomyces cerevisiae. Hamperl S, Brown CR, Perez-Fernandez J, Huber K, Wittner M, Babl V, Stöckl U, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Methods Mol Biol. 2014;1094:329-41. doi: 10.1007/978-1-62703-706-8_26.

Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae. Hamperl S, Brown CR, Garea AV, Perez-Fernandez J, Bruckmann A, Huber K, Wittner M, Babl V, Stoeckl U, Deutzmann R, Boeger H, Tschochner H, Milkereit P, Griesenbeck J. Nucleic Acids Res. 2014 Jan;42(1):e2. doi: 10.1093/nar/gkt891. Epub 2013 Oct 7.

Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. Ohmayer U, Gamalinda M, Sauert M, Ossowski J, Pöll G, Linnemann J, Hierlmeier T, Perez-Fernandez J, Kumcuoglu B, Leger-Silvestre I, Faubladier M, Griesenbeck J, Woolford J, Tschochner H, Milkereit P. PLoS One. 2013 Jul 10;8(7):e68412. doi: 10.1371/journal.pone.0068412. Print 2013.

Chromatin states at ribosomal DNA loci. Hamperl S, Wittner M, Babl V, Perez-Fernandez J, Tschochner H, Griesenbeck J. Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):405-17. doi: 10.1016/j.bbagrm.2012.12.007. Epub 2013 Jan 3. Review.

Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae. Hierlmeier T, Merl J, Sauert M, Perez-Fernandez J, Schultz P, Bruckmann A, Hamperl S, Ohmayer U, Rachel R, Jacob A, Hergert K, Deutzmann R, Griesenbeck J, Hurt E, Milkereit P, Baßler J, Tschochner H. Nucleic Acids Res. 2013 Jan;41(2):1191-210. doi: 10.1093/nar/gks1056. Epub 2012 Dec 2.

RNA polymerase I termination: Where is the end? Németh A, Perez-Fernandez J, Merkl P, Hamperl S, Gerber J, Griesenbeck J, Tschochner H. Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):306-17. doi: 10.1016/j.bbagrm.2012.10.007. Epub 2012 Oct 23. Review.

Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins. Ohmayer U, Perez-Fernandez J, Hierlmeier T, Pöll G, Williams L, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(8):e42449. doi: 10.1371/journal.pone.0042449. Epub 2012 Aug 2.

The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. Reiter A, Hamperl S, Seitz H, Merkl P, Perez-Fernandez J, Williams L, Gerber J, Németh A, Léger I, Gadal O, Milkereit P, Griesenbeck J, Tschochner H. EMBO J. 2012 Aug 15;31(16):3480-93. doi: 10.1038/emboj.2012.185. Epub 2012 Jul 17.

Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes. Jakob S, Ohmayer U, Neueder A, Hierlmeier T, Perez-Fernandez J, Hochmuth E, Deutzmann R, Griesenbeck J, Tschochner H, Milkereit P. PLoS One. 2012;7(3):e32552. doi: 10.1371/journal.pone.0032552. Epub 2012 Mar 14.


Publications of Associated Projects


Ferreira-Cerca, Sébastien (AP1)

Ferreira-Cerca S#*, Kiburu, I#, Thomson E, LaRonde Nicole*, Hurt E*. Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Research. 2014 Jun 19.  # joint first authors. * joint corresponding authors

Thomson E#*, Ferreira-Cerca S#*, Hurt E. Eukaryotic ribosome biogenesis at a glance. J. Cell Sci. 2013 Nov 1;126(Pt 21):4815-21.  # joint first authors. * joint corresponding authors

Ferreira-Cerca S#, Sagar V#, Schäfer T, Diop M, Wesseling AM, Lu H, Chai E, Hurt E, Laronde-Leblanc N. ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat. Struct. Mol. Biol. 2012 Dec;19(12):1316-23. # joint first authors.

 


Hausner, Winfried (AP3)


Németh, Attila (AP4)

Caudron-Herger M.#, Pankert T., Seiler J., Németh A., Voit R., Grummt I., Rippe K.# (2015) Alu element-containing RNAs maintain nucleolar structure and function. EMBO J 34, 2758-74.

Filarsky M.*, Zillner K.*, Araya I.*, Villar-Garea A., Merkl R., Längst G.#, Németh A.# (2015) The extended AT-hook is a novel RNA binding motif. RNA Biol 12, 864-76.

Zillner K., Komatsu J., Filarsky K., Kalepu R., Bensimon A., Németh A. (2015). Active human nucleolar organizer regions are interspersed with inactive rDNA repeats in normal and tumor cells. Epigenomics 7, 363-78.

Hamdane N., Stefanovsky V., Tremblay M.G., Németh A., Paquet E., Lessard F., Sanij E., Hannan R.D. and Moss T. (2014) Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body. PLoS Genet 10, e1004505

Dillinger S.*, Villar-Garea A.*, Deutzmann R., Németh A. (2014). Analysis of histone post-translational modifications from nucleolus-associated chromatin by mass spectrometry. Methods Mol Biol 1094, 277-93.

Németh A. (2014). Methyl-combing—single molecule analysis of DNA modifications on stretched DNA fibers. Methods Mol Biol 1094, 233-41.

Diermeier S., Németh A., Rehli M., Grummt I., Längst G. (2013) Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet 9, e1003786

Zillner K.*, Filarsky M.*, Rachow K., Weinberger M., Längst G.#, Németh A.# (2013) Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Res 41, 5251-62.

Németh A.#, Perez-Fernandez J., Merkl P., Hamperl S., Gerber J., Griesenbeck J., Tschochner H.# (2013). RNA polymerase I termination: where is the end? BBA - Gene Regulatory Mechanisms 1829, 306-17. Review.

Hochstatter J., Hölzel M., Rohrmoser M., Schermelleh L., Leonhardt H., Keough R., Gonda T.J., Imhof A., Eick D., Längst G.#, Németh A.# (2012). Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J Biol Chem 287, 24365-77.

Reiter A.*, Hamperl S.*, Seitz H., Merkl P., Perez-Fernandez J., Williams L., Gerber J., Németh A., Léger I., Gadal O., Milkereit P., Griesenbeck J., Tschochner H. (2012). The Reb1-homolog Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. EMBO J 31, 3480-93.

Zillner K., Németh A. (2012). Single molecule, genome-scale analyses of DNA modifications: exposing the epigenome with next generation technologies. Epigenomics 4, 403-14. Review.


Perez-Fernandez, Jorge (AP2)


Ziegler, Christine (AP5)

  1. STARTSEITE UR

SFB 960

31.8., 14 h, Dr. Konstantin Licht (Medical University of Vienna)

 

 

 

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SFB 960
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