Björn Brembs, Spontaneous Behavior and Operant Learning
Computational analyses of behavioral time series experiments. Automated open data publication. Digital infrastructures for Open Science.
Christoph Engel, Structural Biochemistry of transcription
We use structural Biology tools, such as cryo-Electron Microscopy and X-ray crystallography to elucidate ribonuclear-protein complex structures at atomic resolution. This allows us to study the molecular basis of transcription by eukaryotic RNA-polymerases.
Wolfram Gronwald, Metabolomics by multidimensional NMR
The analysis of small molecules in highly complex biological mixtures such as tissue extracts and body fluids (Metabolomics).
Florian Hartig, Theoretical Ecology
We study theory, models and statistical methods in ecology, evolution and conservation.
Elmar W. Lang, Computer intelligence and machine learning
Machine Learning, Pattern recognition, Neural networks, Deep Learning and explainable Artificial Intelligence (XAI), Image Processing and Biomedical Engineering
Gernot Längst, Chromatin dynamics and generegulation
Chromatin Dynamics; The role of non-coding RNA molecules in Chromatin; rRNA Gene regulation; Epigenetic regulation in chromatin; Functional compartimentalisation of the nucleus and chromatin domain; The role of Chromatin remodeling complexes in Malaria and Cancer; Biophysical Methods to quantify molecular interactions.
Rainer Merkl, Protein Design and Evolution
Sequence- and structure-based algorithms are central tools of molecular biology. In particular, the understanding of protein function and evolution is substantially depending on computational methods that often require the analysis of large datasets.
Remco Sprangers, Biomolecular NMR Spectroscopy
We unravel the atomic mechanism behind large molecular machines. To that end we exploit novel methods in NMR spectroscopy and other advanced structural biology methods.
Christine Ziegler, Structure and function of membrane proteins
We focus on the structure and function of membrane proteins and macromolecular complexes, which are involved in stress-regulated and stress-activated transport processes across the membrane.