Girke P, Fabian S, Aberle L, Seufert W. The spatial arrangement of chromosomes determines fusion of nucleoli in diploid budding yeast. Mol Biol Cell. 2025 Sep 17:mbcE25080375. doi: 10.1091/mbc.E25-08-0375 (externer Link, öffnet neues Fenster). Epub ahead of print. PMID: 40961232.(PubMed (externer Link, öffnet neues Fenster))
Babl V, Girke P, Kruse S, Pinz S, Hannig K, Schächner C, Hergert K, Wittner M, Seufert W, Milkereit P, Tschochner H, Griesenbeck J. Establishment of closed 35S ribosomal RNA gene chromatin in stationary Saccharomyces cerevisiae cells. Nucleic Acids Res. 2024 Nov 11;52(20):12208-12226. PMID: 39373531. doi: 10.1093/nar/gkae838. (externer Link, öffnet neues Fenster) (PubMed) (externer Link, öffnet neues Fenster)
Cardenal P C, Vandroux P, Neumann-Arnold L, Panvert M, Fagart J, Seufert W, Mechulam Y, Schmitt E. (2023) Binding of human Cdc123 to eIF2γ. J Struct Biol. 215(3):108006. PMID 37507029. doi: 10.1016/j.jsb.2023.108006 (externer Link, öffnet neues Fenster) (PubMed (externer Link, öffnet neues Fenster))
Girke P, Seufert W. (2023) Targeting of Hmo1 to subcompartments of the budding yeast nucleolus. Mol Biol Cell 34(3) (PubMed (externer Link, öffnet neues Fenster)) (Mol Biol Cell (externer Link, öffnet neues Fenster))
Pinz S, Doskocil E, Seufert W (2022) Thermofluor-Based Analysis of Protein Integrity and Ligand Interactions. Methods Mol Biol 2533. 247-257. PMID 35796993. doi 10.1007/978-1-0719-2501-9_15 (externer Link, öffnet neues Fenster) (PubMed (externer Link, öffnet neues Fenster))
Vanselow S, Neumann-Arnold L, Wojciech-Moock F, Seufert W (2022) Stepwise assembly of the eukaryotic translation initiation factor 2 complex. JBC 298(2) (PubMed (externer Link, öffnet neues Fenster)) (JBC (externer Link, öffnet neues Fenster))
Hannig K, Babl V, Hergert K, Maier A, Pilsl M, Schächner C, Stöckl U, Milkereit P, Tschochner H, Seufert W, Griesenbeck J (2019) An activator of RNA polymerase I transcription with conserved features from yeast to human. PLoS Genetics 15(2) (PubMed (externer Link, öffnet neues Fenster)) (PloS Genet (externer Link, öffnet neues Fenster))
Girke P, Seufert W. (2019) Compositional reorganization of the nucleolus in budding yeast mitosis. Mol Biol Cell 30(3) (PubMed (externer Link, öffnet neues Fenster)) (Mol Biol Cell (externer Link, öffnet neues Fenster))
A Highlights from MBoC Selection
Höckner S, Neumann-Arnold L, Seufert W. (2016) Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1. Mol Biol Cell 27(14), 2198-2212. (PubMed (externer Link, öffnet neues Fenster)) (Mol Biol Cell (externer Link, öffnet neues Fenster))
A Highlights from MBoC Selection
Recommended in F1000Prime
Yamano H: F1000Prime Recommendation of [Höckner S et al., Mol Biol Cell 2016 27(14):2198-2212]. In F1000Prime, 17 May 2019; 10.3410/f.726381183.793560345
Panvert M, Dubiez E, Arnold L, Perez J, Mechulam Y, Seufert W, Schmitt E. (2015) Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. Structure 23(9), 1596-1608. (PubMed (externer Link, öffnet neues Fenster)) (Structure (externer Link, öffnet neues Fenster))
Arnold L, Höckner S, Seufert W. (2015) Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons. Mol Biol Cell 26(5), 843-858. (PubMed (externer Link, öffnet neues Fenster)) (Mol Bio Cell (externer Link, öffnet neues Fenster))
Perzlmaier AF, Richter F, Seufert W. (2013) Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2). J Biol Chem 288(30):21537-46. (PubMed (externer Link, öffnet neues Fenster)) (J Biol Chem (externer Link, öffnet neues Fenster))
Meitinger F, Richter H, Heisel S, Hub B, Seufert W, Pereira G. (2013) A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity. PLoS Biol. 11(2):e1001495. (PubMed (externer Link, öffnet neues Fenster)) (PLoS Biol (externer Link, öffnet neues Fenster))
Wittner M, Hamperl S, Stöckl U, Seufert W, Tschochner H, Milkereit P, Griesenbeck J. (2011) Establishment and maintenance of alternative chromatin states at a multicopy gene locus. Cell 145(4):543-54. (PubMed (externer Link, öffnet neues Fenster)) (Cell (externer Link, öffnet neues Fenster))
Geil, C, Schwab, M, Seufert, W. (2008) A nucleolus-localized activator of Cdc14 phosphatase supports rDNA segregation in yeast mitosis. Current Biology 18, 1001-05. (PubMed (externer Link, öffnet neues Fenster)) (Current Biology (externer Link, öffnet neues Fenster))
Dirscherl, G., Schwab, M., Seufert, W., König, B. (2008) Enhancing the separation of phosphorylated proteins in gel electrophoresis with dinuclear bispyridylmethylamine- tyrosine-acrylamide complexes. Inorganica Chimica Acta, (ScienceDirect (externer Link, öffnet neues Fenster))
Willems, A.R., Schwab, M., Tyers, M. (2004) A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin. Biochim. Biophys. Acta 1695, 133-170 (PubMed (externer Link, öffnet neues Fenster))
Schwab, M., Tyers, M. (2001) Cell cycle. Archipelago of destruction. Nature 413, 268-269 (PubMed (externer Link, öffnet neues Fenster))
Schwab, M., Neutzner, M., Möcker, D., Seufert, W. (2001) Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC. EMBO J. 20, 5165-5175 (PubMed (externer Link, öffnet neues Fenster))
Menssen, R., Neutzner, A., Seufert, W. (2001) Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis. Current Biology 11, 345-350 (PubMed (externer Link, öffnet neues Fenster))
Zachariae, W., Schwab, M., Nasmyth, K., Seufert, W. (1998) Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. Science 282, 1721-1724 (PubMed (externer Link, öffnet neues Fenster))
Schwab, M., Schulze Lutum, A., Seufert, W. (1997) Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90, 683-693 (PubMed (externer Link, öffnet neues Fenster))
Betting, J., Seufert, W. (1996) A yeast Ubc9 mutant protein with temperature-sensitive in vivo function is subject to conditional proteolysis by a ubiquitin- and proteasome-dependent pathway. J. Biol. Chem. 271, 25790-25796 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Futcher, B., Jentsch, S. (1995) Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature 373, 78-81 (PubMed (externer Link, öffnet neues Fenster))
Johnson, E., Bartel, B., Seufert, W., Varshavsky, A. (1992) Ubiquitin as a degradation signal. EMBO J. 11, 497-505 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Jentsch, S. (1992) In vivo function of the proteasome in the ubiquitin pathway. EMBO J. 11, 3077-3080 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., McGrath, J.P., Jentsch, S. (1990) UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation. EMBO J. 9, 4535-4541 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Jentsch, S. (1990) Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins. EMBO J. 9, 543-550 (PubMed (externer Link, öffnet neues Fenster))
Seufert,W., Jentsch, S. (1990) Nucleotide sequence of two tRNAArg-tRNAAsp tandem genes linked to duplicated UBC genes in Saccharomyces cerevisiae. Nucleic Acids Res. 18, 1638 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W. (1990) Nucleotide sequence of the yeast SDH1 gene encoding a serine dehydratase homolog. Nucleic Acids Res. 18, 3653 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Lurz, R., Messer, W. (1988) A novel replicon occuring naturally in Escherichia coli is a phage-plasmid hybrid. EMBO J. 7, 4005-4010 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Dobrinski, B., Lurz, R., Messer, W. (1988) Functionality of the DnaA protein binding site in DNA replication is orientation dependent. J. Biol. Chem. 263, 2719-2723 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Messer, W. (1987) Start sites for bidirectional in vitro replication inside the replication origin, oriC, of Escherichia coli. EMBO J. 62469-2472 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Messer, W. (1987) DnaA protein binding to the plasmid origin region can substitute for primosome assembly during replication of pBR322 in vitro. Cell 48, 73-78 (PubMed (externer Link, öffnet neues Fenster))
Seufert, W., Messer, W. (1986) Initiation of Escherichia coli minichromosome replication at oriC and protein n’ recognition sites.Two modes for initiating DNA synthesis in EMBO J.5, 3401-3406 (PubMed (externer Link, öffnet neues Fenster))