Forschungsschwerpunkt
Our research investigates the neuronal mechanisms underlying behavioural prioritization when internal drives, such as hunger and social motivation, come into conflict. We focus on the role of oxytocin, a neuropeptide mainly produced in the hypothalamus, which is implicated in the modulation of social behaviour, emotional regulation, reward processing, and energy balance. Specifically, we examine how OXT signalling contributes to the selection and ranking of competing motivational states in male mice, using a social versus food preference paradigm. Although individual motivational circuits have been well characterized, the integrative processes that enable the brain to evaluate and prioritize conflicting needs remain poorly understood. To dissect these mechanisms, we combine behavioural testing with pharmacological intervention, neuroanatomical tracing, chemogenetic manipulation, and molecular analyses. This work is part of the DFG-funded GRK2174 graduate program, "Neurobiology of Emotion Dysfunctions".
Funding
2023-2026 DFG under GRK 2174 “Neurobiology of Emotion Dysfunctions”