We use most techniques of optical molecular spectroscopy and many of them in microplates. We cover reflectometry, photometry, polarimetry, circular dichroism and all parameters of luminescence (intensity, polarization, lifetime, delayed luminescence, electrochemiluminescence and chemiliminescence. Optical sensors are measured continuously in flow-through, via fiber optics or in microplates. Reading of DNA and protein arrays on glass and other substrates with a laserscanner is also offered.
Ion analyses can performed optically and can be are validated by atomic spectroscopy. For this purpose, we are running an inductively-coupled plasma atomic emission spectroscopy instrument (Spectroflame) and an inductively-coupled plasma mass spectrometer (PE Elan 9000). The atomic spectroscopy facilities are also available for all groups of the faculty and of the university that require trace element quantitation.
Selected publication:
- Assmann N, Dettmer K, Simbuerger JMB, Broeker C, Nuernberger N, Renner-Sattler K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J*, 2016, Renal Fanconi´s Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy, Cell Rep 15:1423-1429, DOI: 10.1016/j.celrep.2016.04.037.