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Sensors & Actuators for Animal Cells

 

Bild: Logo Arbeitsgruppe Prof. Wegener
Bild: EMFT

Our lab is focused on interfacing animal cells (2D monolayers or 3D aggregates) with physical transducers (e.g. planar electrodes, piezoelectric devices, optical waveguides) to monitor the cell response during toxicological or pharmacological assays non-invasively and in real-time. The non-invasive nature of the measurement provides the dynamics of the cell response as another level of biological insight. It is the longterm goal of our research to replace classical concentration-analysis by effect-analysis on biological organisms in general, and animal cells in particular. To increase the information content we combine individual transducer principles in one setup and include invasive actuators (electroporation, electrofusion, electrodeformation) to expand the scope of label-free analysis.

Barrier Analysis of 2D-Tissues (externer Link, öffnet neues Fenster)

Barrier Analysis of 2D-Tissues - Porous Surfaces

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