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University of Regensburg
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Research

Sensors & Actuators for Animal Cells

 

Picture: Logo working group Prof. Wegener
Picture: EMFT

Our lab is focused on interfacing animal cells (2D monolayers or 3D aggregates) with physical transducers (e.g. planar electrodes, piezoelectric devices, optical waveguides) to monitor the cell response during toxicological or pharmacological assays non-invasively and in real-time. The non-invasive nature of the measurement provides the dynamics of the cell response as another level of biological insight. It is the longterm goal of our research to replace classical concentration-analysis by effect-analysis on biological organisms in general, and animal cells in particular. To increase the information content we combine individual transducer principles in one setup and include invasive actuators (electroporation, electrofusion, electrodeformation) to expand the scope of label-free analysis. (external link, opens in a new window)

Impedimetric Whole-Cell Biosensors (external link, opens in a new window)

Impedimetric Whole-Cell Biosensors - Goldfilm Electrodes

Biosensors for Cytomechanics (external link, opens in a new window)

Biosensors for Cytomechanics - Acoustic Resonators

In Situ Electroporation (external link, opens in a new window)

In Situ Electroporation

Chemical Analysis of Animal Cells by Mass Spectrometry (external link, opens in a new window)

Chemical Analysis of Animal Cells by Mass Spectrometry

Barrier Analysis of 2D-Tissues (external link, opens in a new window)

Barrier Analysis of 2D-Tissues - Porous Surfaces

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