Dr. rer. nat. Wilhelm Malloni

Courses

SS 2014

Research focus

• fMRI analysis with SPM

• Magnetic resonance spectroscopy (MRS)

• Machine learning

• Computational methods for separating multivariate signals (ICA)

• Time series analysis with nonparametric methods (SSA)

• Orthogonal data transformation (PCA)

Current projects

• Eye-tracking experiments

Journal articles

• PSCD Domains of Pleuralin-1 from the Diatom Cylindrotheca fusiformis: NMR Structures and Interactions with Other Biosilica-Associated Proteins. De Sanctis S., Wenzler M., Kröger N., Malloni WM., Sumper M., Deutzmann R., Zadravec P., Brunner E., Kremer W., Kalbitzer HR. Structure. 2016 Jul 6;24(7):1178-91. doi: 10.1016/j.str.2016.04.021

• Comparative analysis of solvent artifact removal from NMR spectra: SSA and ICA. S. De Sanctis, W.M. Malloni, W. Kremer, A.M. Tomé, E. W. Lang, K.P. Neidig, H.R. Kalbitzer. Trends Applied Spectroscopy 9, 1-15, 2012.

• Singular Spectrum Analysis for solvent artifact removal from one-dimensional NMR spectra. S. De Sanctis, W.M. Malloni, W. Kremer, A.M. Tomé, E. W. Lang, K.P. Neidig, H.R. Kalbitzer. Journal of Magnetic Resonance 210 (2),177-183, 2011.

• Automated solvent artifact removal and base plane correction from multidimensional NMR protein spectra by AUREMOL-SSA. W. M. Malloni, S. De Sanctis, A.M. Tomé, E.W. Lang, C. Munte, K. Stadlthanner, K.P. Neidig, H.R. Kalbitzer. Journal of Bimolecular NMR 47 (2),110-111, 2010.

Conference contributions

Talks

• W. M. Malloni (2008). Computational method lecture: Automated Removal of Water Artifact from Protein 2D NMR Spectra: SSA. 30th Discussion Meeting Gesellschaft Deutscher Chemiker (GDCh) Regensburg, Germany.

Posters

• W. M. Malloni, S. De Sanctis, E. W. Lang and H. R. Kalbitzer (2012). A comparative inspection of Independent Component Analysis (ICA) and Singular Spectrum Analysis (SSA) for solvent artifact suppression. Advanced Magnetic Resonance for the Study of Dynamics in Biomolecules and Materials, 34th Discussion Meeting (GDCh) in Halle (Saale), Germany.

• S. De Sanctis, M. Wenzler, W. M. Malloni, E. Brunner, N. Kroeger and H. R. Kalbitzer (2012). Solution structure of the diatom cell wall protein pleuralin-1. Advanced Magnetic Resonance for the Study of Dynamics in Biomolecules and Materials, 34th Discussion Meeting (GDCh) in Halle (Saale), Germany.

• T. Harsch, H. Donaubauer, W. M. Malloni, S. De Sanctis, K. P. Neidig, H. R. Kalbitzer (2011). Promising new modules for data processing via the AUREMOL-SSA/ICA and protein quality control. Discussion Meeting of the MR spectroscopy division of the GDCh, EUROMAR 2011, Frankfurt am Main, Germany.

• W. M. Malloni, S. De Sanctis, C. Munte, K. P. Kneidig, H. R. Kalbitzer (2010). Protein structural changes identification via automated hybrid local multidimensional spectral comparison. Development and Application of Modern Techniques in Chemistry, Life Sciences and Material Research, 32nd Discussion Meeting (GDCh) in Münster, Germany.

• S. De Sanctis, W. M. Malloni, E. W. Lang, W. Kremer, K. P. Neidig, H. R. Kalbitzer (2010). Solvent Artefact Removal from 1D Spectra of Biofluids and Compounds by means of Auremol-SSA Routine. Development and Application of Modern Techniques in Chemistry, Life Sciences and Material Research, 32nd Discussion Meeting (GDCh) in Münster, Germany.

• H. R. Kalbitzer, W. M. Malloni, S. De Sanctis, A. M. Tome, K. P. Neidig, E. W. Lang, W. Kremer (2010). Automated Solvent Artifact Removal and Base Plane Correction of Mutidimensional NMR Protein Spectra by AUREMOL-SSA. Folding and Misfolding, ICMR in Biological Systems in Cairns, Australia

• W. M. Malloni, S. De Sanctis, E. W. Lang, C. Munte, K. P. Neidig, H. R. Kalbitzer (2010). Singular Spectrum Analysis for Solvent Artifact Removal from Digitally Filtered Multidimensional Data. Deutsche Physikalische Gesellschaft (DPG), Regensburg, Germany

• W. M. Malloni, S. De Sanctis, K. Brunner, K. P. Neidig, H. R. Kalbitzer (2009). Multidimensional Automated Peak Volume Calculation based on the Levenberg-Marquardt algorithm. Magnetic Resonance in Chemistry and Materials Research, 31th Discussion Meeting (GDCh) Dresden, Germany.

• S. De Sanctis, W. M. Malloni, E. W. Lang, C. Munte, K. P. Neidig, H. R. Kalbitzer (2009). Normalized Singular Spectrum Analysis for Solvent Artifact Removal from Digitally Filtered Multidimensional Data. Magnetic Resonance in Chemistry and Materials Research, 31th Discussion Meeting (GDCh) Dresden, Germany

• S. De Sanctis, W. M. Malloni, E. W. Lang, C. Munte, K. P. Neidig, K. Brunner, H. R. Kalbitzer (2008). Automated Removal of Water Artifact from Protein 2D NMR Spectra: SSA. Magnetic Resonance in Biology and Chemistry 30th Discussion Meeting (GDCh) Regensburg, Germany.