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Publikationen

          

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Fakultät für Biologie und Vorklinische Medizin
Institute für Anatomie
Lehrstuhl für Molekulare und Zelluläre Anatomie
PUBLIKATIONEN

 


         

         

Publikationsliste

                   

(25) Haerteis S, Schork A, Dörffel T, Bohnert BN, Nacken R, Wörn M, Xiao M, Essigke D, Janessa A, Schmaier AH, Feener E, Häring HU, Bertog M, Korbmacher C, and Artunc F (2018). Plasma kallikrein activates epithelial sodium channel (ENaC) in vitro, but is not essential for volume retention in nephrotic mice. Acta Physiol (Oxf). 2018 Sep; 224(1): e13060.  PDF

(24) Ilyaskin AV, Kirsch SA, Böckmann RA, Sticht H, Korbmacher C, Haerteis S, Diakov A. The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids. Pflügers Archiv 2018 Jul; 470(7): 1087-1102.  PDF

(23) Bohnert BN, Menacher M, Janessa A, Wörn M, Schork A, Daiminger S, Kalbacher H, Häring HU, Daniel C, Amann K, Sure F, Bertog M, Haerteis S, Korbmacher C, Artunc F (2018). Aprotinin prevents proteolytic ENaC activation and volume retention in nephrotic syndrome. Kidney International 93, 159-172.  PDF

(22)Sostegni S, Diakov A, McIntyre P, Bunnett N,, Korbmacher C, Haerteis S (2017). Erratum to: Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase. Pflügers Archiv 469, 845-846. PDF

(21) Ilyaskin A, Diakov A, Korbmacher C, Haerteis S (2017). Bile acids potentiate proton-activated currents in Xenopus laevis oocytes expressing human acid-sensing ion channel (ASIC1a). Physiol Rep 5 (3), e13132.  PDF

(20) Ilyaskin A, Diakov A, Korbmacher C, Haerteis S (2016). Activation of the human epithelial sodium channel (ENaC) by bile acids involves the degenerin site. J Biol Chem 291,19835-19847.  PDF

(19) Schork A, Woern M, Kalbacher H, Voelter W, Nacken R, Bertog M, Haerteis S, Korbmacher C, Heyne N, Peter A, Häring HU, Artunc F (2016). Association of plasminuria with overhydration in patients with CKD. Clin J Am Soc Nephrol 11, 761-769.  PDF

(18) Jeggle P, Smith ES, Stewart AP, Haerteis S, Korbmacher C, Edwardson JM (2015). Atomic force microscopy imaging reveals the formation of ASIC/ENaC cross-clade ion channels. Biochem Biophys Res Commun 464, 38-44.  PDF

(17) Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW (2015). Neutrophil elastase activates PAR2 and TRPV4 to cause inflammation and pain. J Biol Chem. 290, 13875-13887.  PDF

(16) Sostegni S, Diakov A, McIntyre P, Bunnett NW, Korbmacher C, Haerteis S (2015). Sensitisation of TRPV4 by PAR₂ is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase. Pflügers Archiv 467, 687-701. PDF

(15) Haerteis S, Krappitz A, Krappitz M, Murphy JE, Bertog M, Krueger B, Nacken R, Chung H, Hollenberg MD, Knecht W, Bunnett NW, Korbmacher C (2014). Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites. J Biol Chem 289, 19067-19078.  PDF

(14) Krappitz M, Korbmacher C, Haerteis S (2014). Demonstration of proteolytic activation of the epithelial sodium channel (ENaC) by combining current measurements with detection of cleavage fragments. J Vis Exp 5, 89.  PDF

(13) Lieu T, Jayawerra G, Zhao P, Poole D, Jensen D, Grace M, McIntyre P, Bron R, Wilson YM, Krappitz M, Haerteis S, Korbmacher C, Steinhoff MS, Nassini R, Materazzi S, Geppetti P, Corvera CU, Bunnett NW (2014). The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice. Gastroenterology 147, 1417-28.  PDF

(12) Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis N, Jensen D, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindstrom E, Guerrero-Alba R, Valdez-Morales E, Liedtke W, McIntyre P, Vanner S, Korbmacher C, Bunnett NW (2014). Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
J Biol Chem 289, 27215-34.  PDF

(11) Lefèvre CMT, Diakov A, Haerteis S, Korbmacher C, Gründer S, Wiemuth D (2014). Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC). Pflügers Archiv 466, 253-63.  PDF

(10) Rauh R, Soell D, Haerteis S, Diakov A, Nesterov V, Krueger B, Sticht H, Korbmacher C (2013). A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect. Am J Physiol Lung Cell Mol Physiol 304,L43-55.  PDF

(9) Haerteis S, Krappitz M, Diakov A, Krappitz A, Rauh R, Korbmacher C (2012). Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ-subunit of the human epithelial sodium channel (ENaC). J Gen Physiol 140, 375-89.  PDF

(8) Haerteis S, Krappitz M, Bertog M, Krappitz A, Baraznenok V, Henderson I, Lindström E, Murphy JE, Bunnett NW, Korbmacher C (2012). Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S. Pflügers Archiv 464, 353-65.  PDF

(7) Haerteis S, Schaal D, Brauer F, Brüschke S, Schweimer K, Rauh R, Sticht H, Rösch P, Schwarzinger S, Korbmacher C (2012). An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation. Cell Physiol Biochem 29, 761-774.  PDF

(6) Krueger B, Schlötzer-Schrehardt U, Haerteis S, Zenkel M, Chankiewitz VE, Amann KU, Kruse FE, Korbmacher C (2012). Four subunits (αβγδ) of the epithelial sodium channel (ENaC) are expressed in the human eye in various locations. Invest Ophthalmol Vis Sci 53, 596-604.  PDF

(5) Stewart AP, Haerteis S, Diakov A, Korbmacher C, Edwardson JM (2011). Atomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC). J Biol Chem 286, 31944-31952.  PDF

(4) Huber R, Krueger B, Diakov A, Korbmacher J, Haerteis S, Einsiedel J, Gmeiner P, Azad AK, Cuppens H, Cassiman JJ, Korbmacher C, Rauh R (2010). Functional characterization of a partial loss-of-function mutation of the epithelial sodium channel (ENaC) associated with atypical cystic fibrosis. Cell Physiol Biochem 25, 145-158.  PDF

(3) Haerteis S, Krueger B, Korbmacher C, Rauh R (2009). The δ-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation. J Biol Chem 284, 29024-29030.  PDF

(2) Krueger B, Haerteis S, Yang L, Hartner A, Rauh R, Korbmacher C, Diakov A (2009). Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1. Cell Physiol Biochem 24, 605-618.  PDF

(1) Svenningsen P, Bistrup C, Friis UG, Bertog M, Haerteis S, Krueger B, Stubbe J, Jensen OL, Thiesson HC, Uhrenholt TR, Jespersen B, Jensen BL, Korbmacher C, Skøtt O (2009). Plasmin in nephrotic urine activates the epithelial sodium channel.
J Am Soc Nephrol 20, 299-310.  PDF
 

  1. Fakultät für Biologie und Vorklinische Medizin
  2. Faculty Research

Prof. Dr. Silke Härteis

Professur für Molekulare und Zelluläre Anatomie

silke.haerteis@ur.de

Universität Regensburg

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Universitätsstraße 31

93053 Regensburg

Tel.:  +49 (0)941 943-2879

Fax:  +49 (0)941 943-2868