The main objective of our research is the complex process of eukaryotic ribosome biogenesis. Ribosome synthesis involves transcription of ribosomal RNA genes, processing and assembly of ribosomal precursor molecules in the nucleolus and the nucleus, their transport to the cytoplasm and final maturation.
Several research teams are dedicated to approach this scientific problem. To this end the individual teams are strongly interconnected to solve specific questions in a common effort. The combination of expert knowledge in the fields of transcriptional regulation, chromatin structure and remodeling, ribosomal subunit processing and assembly will allow us to gain further insights in this fascinating topic.