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PROCOS

Computational Analysis of Protein-Protein Complexes.

PROCOS is a novel approach for the evaluation of both computationally and experimentally derived protein-protein complexes.

Based on three scoring functions (intermolecular electrostatic energy, intermolecular van der Waals energy and an amino acid based pair potential) a support vector machine is trained and provides a global estimation for your uploaded complex called "PROCOS probability" to be native.

PROCOS is available as a webservice.


  1. Department of Medicine
  2. Institute of Functional Genomics