Prof Dr Thomas Jaki

A Preplanned Multi‐Stage Platform Trial for Discovering Multiple Superior Treatments With Control of FWER and Power. (external link, opens in a new window)

Greenstreet, Peter, Jaki, Thomas , Bedding, Alun und Mozgunov, Pavel (2024)

Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data. (external link, opens in a new window)

Burdon, Abigail J., Baird, Richard D. und Jaki, Thomas  (2024)

A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies. (external link, opens in a new window)

Jaki, Thomas , Barnett, Helen, Titman, Andrew und Mozgunov, Pavel (2024)

Group sequential designs for clinical trials when the maximum sample size is uncertain. (external link, opens in a new window)

Yarahmadi, Amin, Dodd, Lori E., Jaki, Thomas , Horby, Peter und Stallard, Nigel (2024)

Validation of predicted individual treatment effects in out of sample respondents. (external link, opens in a new window)

Kuhlemeier, Alena, Jaki, Thomas , Witkiewitz, Katie, Stuart, Elizabeth A. und Van Horn, M. Lee (2024)

A multi‐arm multi‐stage platform design that allows preplanned addition of arms while still controlling the family‐wise error. (external link, opens in a new window)

Greenstreet, Peter, Jaki, Thomas , Bedding, Alun, Harbron, Chris und Mozgunov, Pavel (2024)

Adding experimental treatment arms to multi‐arm multi‐stage platform trials in progress. (external link, opens in a new window)

Burnett, Thomas, König, Franz und Jaki, Thomas  (2024)

Joint TITE-CRM: A Design for Dose Finding Studies for Therapies with Late-Onset Safety and Activity Outcomes. (external link, opens in a new window)

Barnett, Helen, Boix, Oliver, Kontos, Dimitris und Jaki, Thomas  (2024)

A comparison of model-free phase I dose escalation designs for dual-agent combination therapies. (external link, opens in a new window)

Barnett, Helen, George, Matthew, Skanji, Donia, Saint-Hilary, Gaelle, Jaki, Thomas  und Mozgunov, Pavel (2024)

Predicting Individual Treatment Effects: Challenges and Opportunities for Machine Learning and Artificial Intelligence. (external link, opens in a new window)

Jaki, Thomas , Chang, Chi, Kuhlemeier, Alena und Van Horn, M. Lee (2024)

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (external link, opens in a new window)

Yap, Christina , Solovyeva, Olga , de Bono, Johann , Rekowski, Jan , Patel, Dhrusti , Jaki, Thomas , Mander, Adrian , Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S , Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi  und Weir, Christopher J (2023)

Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing. (external link, opens in a new window)

Law, Martin, Couturier, Dominique-Laurent, Choodari-Oskooei, Babak, Crout, Phillip, Gamble, Carrol, Jacko, Peter, Pallmann, Philip, Pilling, Mark, Robertson, David S., Robling, Michael, Sydes, Matthew R., Villar, Sofía S., Wason, James, Wheeler, Graham, Williamson, S. Faye, Yap, Christina und Jaki, Thomas  (2023)

Reducing intrusive memories after trauma via an imagery-competing task intervention in COVID-19 intensive care staff: a randomised controlled trial (external link, opens in a new window).

Iyadurai, Lalitha, Highfield, Julie, Kanstrup, Marie, Markham, Alfred, Ramineni, Varsha, Guo, Boliang, Jaki, Thomas , Kingslake, Jonathan, Goodwin, Guy M., Summers, Charlotte, Bonsall, Michael B. und Holmes, Emily A. (2023)

Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design. (external link, opens in a new window)

Serra, Alessandra , Mozgunov, Pavel, Davies, Geraint und Jaki, Thomas (2023)

Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study. (external link, opens in a new window)

Solovyeva, Olga , Dimairo, Munyaradzi , Weir, Christopher J. , Hee, Siew Wan , Espinasse, Aude, Ursino, Moreno, Patel, Dhrusti , Kightley, Andrew, Hughes, Sarah, Jaki, Thomas , Mander, Adrian, Evans, Thomas R. Jeffry, Lee, Shing, Hopewell, Sally, Rantell, Khadija Rerhou, Chan, An-Wen, Bedding, Alun, Stephens, Richard, Richards, Dawn, Roberts, Lesley, Kirkpatrick, John, de Bono, Johann  und Yap, Christina  (2023)

Exploring the issues that influence how people with rare neurological conditions engage in physical activity. (external link, opens in a new window)

Buscemi, Valentina, Boaz, Annette, Dawes, Helen, Jaki, Thomas , Jones, Fiona, Marsden, Jonathan, Paul, Lorna, Playle, Rebecca, Randell, Elizabeth, Robling, Michael, Rochester, Lynn, Busse, Monica und Ramdharry, Gita (2023)

Early phase clinical trials in oncology: Realising the potential of seamless designs (external link, opens in a new window)

Jaki, Thomas , Burdon, Abigail , Chen, Xijin , Mozgunov, Pavel, Zheng, Haiyan  und Baird, Richard  (2023)

A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering. (external link, opens in a new window)

Serra, Alessandra , Mozgunov, Pavel und Jaki, Thomas  (2023)

Treating intrusive memories after trauma in healthcare workers: a Bayesian adaptive randomised trial developing an imagery-competing task intervention. (external link, opens in a new window)

Ramineni, Varsha , Millroth, Philip, Iyadurai, Lalitha, Jaki, Thomas , Kingslake, Jonathan , Highfield, Julie, Summers, Charlotte , Bonsall, Michael B. und Holmes, Emily A.  (2023)

Point estimation for adaptive trial designs II: Practical considerations and guidance. (external link, opens in a new window)

Robertson, David S., Choodari‐Oskooei, Babak, Dimairo, Munya , Flight, Laura, Pallmann, Philip  und Jaki, Thomas  (2023)

Online error rate control for platform trials. (external link, opens in a new window)

Robertson, David S., Wason, James M. S. , König, Franz, Posch, Martin  und Jaki, Thomas  (2023)

Backfilling cohorts in phase I dose-escalation studies (external link, opens in a new window)

Barnett, Helen, Boix, Oliver, Kontos, Dimitris und Jaki, Thomas  (2023)

Updating the probability of study success for combination therapies using related combination study data. (external link, opens in a new window)

Graham, Emily , Harbron, Chris und Jaki, Thomas  (2023)

A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method. (external link, opens in a new window)

Daniells, Libby , Mozgunov, Pavel, Bedding, Alun und Jaki, Thomas  (2023)