An R/Bioconductor package for two-condition microarray experiments. Includes computation of scores, empirical p-values and local false discovery rates.
|twilight is an R/Bioconductor package that includes several functions for the statistical analysis of two-condition microarray data. The main algorithm for estimating the local false discovery rate is described in Scheid and Spang (2004a). The newer versions of twilight include the permutation filtering algorithm introduced in Scheid and Spang (2006).
For further information please visit the compdiag projects Local False Discovery Rate or Permutation Filtering.
Download the package source or windows binary directly from the Bioconductor WWW-site. To run the package, you need R or higher and the R packages splines and stats. Package twilight includes a user's manual which can be downloaded separately from above.
For commercial use of TWILIGHT, please visit the webpage of the NGFN Technology Transfer Center on genome-marketplace.