Biochemistry, biophysics, bioinformatics

Prof. Dr. Patrick Babinger

• Important information: We are interested in the characterisation of previously unknown enzymes, especially those in the context of ether lipid biosynthesis, and of enzymes that can bind nucleic acids in addition to their catalytic activity.

Dr. Astrid Bruckmann

• Important information: Our group aims at providing state-of-the-art mass spectrometric methods which are tailored to the project specific requirements of our collaboration partners within the RCB and beyond. We are particularly focusing our interest on quantitative proteomics, interactomics (RNA-and protein proximity labeling workflows), cross-link (XL)-MS methods, analysis of post-translational modifications as well as nascent proteomics.

Prof. Dr. Neva Caliskan

• Important information: Neva Caliskan's research group investigates the role of RNA molecules in non-canonical translation events that can influence the interaction between host and pathogen. Their goal is to shed light on therapeutic RNA-protein complexes as new targets in the fight against infections.

Prof. Dr. Thomas Dresselhaus

• Important information: We are studying gene regulatory networks during plant germline and seed development, fertilization mechanisms, also under environmental stress.

Prof. Dr. Klaus Grasser

• Important information: We study how RNAPII transcript elongation and co-transcriptional processes in the chromatin context impact development and stress responses in plants

Prof. Dr. Joachim Griesenbeck

• Important information: Through our research, we aim to gain a better understanding of chromatin structure and the regulation of eukaryotic gene transcription.

PD Dr. Andrea Hupfeld

• Important information: Our goal is to leverage light-sensitive unnatural amino acids as synthetic tools for enzymology and application-based enzyme engineering.

Prof. Dr. Aline Koch

• Important information: We study how regulatory non-coding and coding RNAs can be used as "sprayable RNAs" to improve the agricultural value of crops

Prof. Dr. Gernot Längst

• Important information: The packaging of eukaryotic DNA into chromatin presents an overriding regulatory layer to all DNA dependent processes, like transcription or replication.

Prof. Dr. Gunter Meister

• Important information: Cellular Biochemistry and Biophysics

Dr. Nina Ripin

• Important information: We use interdisciplinary strategies to investigate the properties, biological functions, and disease relevance of stress-induced ribonucleoprotein (RNP) granules. Our research focuses on the role of RNA and its interactions with RNA chaperones—such as DEAD-box helicases and RNA-modifying enzymes—in shaping the integrated stress response.

Prof. Dr. Till Rudack

• Important information: Our goal is to gain cross-scale, time-resolved atomic insights into the structure, dynamics and function of molecular machines with biomedical or biotechnological relevance. To this end, we develop and apply computational strategies that combine different methods from bioinformatics, theoretical biophysics and quantum chemistry.

Dr. Timo Schlemmer

• Important information: Our research focus is dedicated to the development and production of innovative RNA-based crop protection agents based on circular RNAs. Our goal is to develop sustainable alternatives to chemically synthetic pesticides and to bring them to market in the future.
  

Prof. Dr. Remco Sprangers

• Important information: The primary scientific goal of our research is to understand the relationship between protein motions and protein function

Prof. Dr. Reinhard Sterner

• Important information: Our research focuses on enzymes, i.e. complex proteins that catalyze cellular reactions with high specificity and efficiency.