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• "Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening", Seitz, Thoma, Schoch, Stihle, Benz, D'Arcy, Wiget, Ruf, Hennig, Sterner, 2010

  Publication

  The human glucocorticoid receptor ligand-binding domain (hGR-LBD) is an important drug target for the treatment of various diseases. However, the low...

  Publication on epub.uni-regensburg.de: "Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening" (external link, opens in a new window)

• "Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds", Richter, Bosnali, Carstensen, Seitz, Durchschlag, Blanquart, Merkl, Sterner, 2010

  Publication

  The evolution of the prototypical (beta alpha)(8)-barrel protein imidazole glycerol phosphate synthase (HisF) was studied by complementary...

  Publication on epub.uni-regensburg.de: "Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds" (external link, opens in a new window)

• "The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy", Liebold, List, Kalbitzer, Sterner, Brunner, 2010

  Publication

  The imidazole glycerol phosphate (ImGP) synthase from the hyperthermophilic bacterium Thermotoga maritima is a 1:1 complex of the glutaminase subunit...

  Publication on epub.uni-regensburg.de: "The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy" (external link, opens in a new window)

• "Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry", Ehrmann, Richter, Busch, Reimann, Albers, Sterner, 2010

  Publication

  The prototypical tryptophan synthases form a stable heterotetrameric alpha beta beta alpha complex in which the constituting TrpA and TrpB1 subunits...

  Publication on epub.uni-regensburg.de: "Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry" (external link, opens in a new window)

• "Hyperthermostable acetyl xylan esterase", Drzewiecki, Angelov, Ballschmiter, Tiefenbach, Sterner, Liebl, 2010

  Publication

  An esterase which is encoded within a Thermotoga maritima chromosomal gene cluster for xylan degradation and utilization was characterized after...

  Publication on epub.uni-regensburg.de: "Hyperthermostable acetyl xylan esterase" (external link, opens in a new window)

• "Computational and Experimental Evidence for the Evolution of a (betaalpha)(8)-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds", Richter, Bosnali, Carstensen, Seitz, Durchschlag, Blanquart, Merkl, Sterner, 2010

  Publication

  The evolution of the prototypical (beta alpha)(8)-barrel protein imidazole glycerol phosphate synthase (HisF) was studied by complementary...

  Publication on epub.uni-regensburg.de: "Computational and Experimental Evidence for the Evolution of a (betaalpha)(8)-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds" (external link, opens in a new window)

• "Stabilization of a Metabolic Enzyme by Library Selection in Thermus thermophilus", Schwab, Sterner, 2011

  Publication

  The anthranilate phosphoribosyl transferase from the hyper-thermophilic archaeon Sulfolobus solfataricus (sAnPRT, encoded by strpD), which catalyzes...

  Publication on epub.uni-regensburg.de: "Stabilization of a Metabolic Enzyme by Library Selection in Thermus thermophilus" (external link, opens in a new window)

• "Related (βα)8‐Barrel Proteins in Histidine and Tryptophan Biosynthesis: A Paradigm to Study Enzyme Evolution", List, Sterner, Wilmanns, 2011

  Publication

  ChemBioChem 1439-4227,1439-4227 10.1002/cbic.201100082

  Publication on epub.uni-regensburg.de: "Related (βα)8‐Barrel Proteins in Histidine and Tryptophan Biosynthesis: A Paradigm to Study Enzyme Evolution" (external link, opens in a new window)

• "Functional Assignment of an Enzyme that Catalyzes the Synthesis of an Archaea-Type Ether Lipid in Bacteria", Guldan, Matysik, Bocola, Sterner, Babinger, 2011

  Publication

  Angewandte Chemie International Edition 10.1002/anie.201101832

  Publication on epub.uni-regensburg.de: "Functional Assignment of an Enzyme that Catalyzes the Synthesis of an Archaea-Type Ether Lipid in Bacteria" (external link, opens in a new window)

• "A Fast and Precise Approach for Computational Saturation Mutagenesis and its Experimental Validation by Using an Artificial (βα)8-Barrel Protein", Fischer, Seitz, Lochner, Sterner, Merkl, Bocola, 2011

  Publication

  We present a computational saturation mutagenesis protocol (CoSM) that predicts the impact on stability of all possible amino acid substitutions for a...

  Publication on epub.uni-regensburg.de: "A Fast and Precise Approach for Computational Saturation Mutagenesis and its Experimental Validation by Using an Artificial (βα)8-Barrel Protein" (external link, opens in a new window)