Meet & Greet at UR. © UR | Photo: Julia Dragan
With Regensburg’s Center for Immunomedicine in Transplantation and Oncology (CITO), excellent (infra-)structures will be created for the conduction of an outstanding research program in the field of immunomedicine. Overcoming working group boundaries, scientists will do research together in interdisciplinary project areas. They will be provided with top-notch core facilities and tailor-made technology platforms in a new research building on campus, currently under construction.
CITO will link the scientific focus areas of immunotherapy, tumor research and transplantation medicine at UR even more closely and become the nucleus for cooperation with other Regensburg based institutions such as the Regensburg Center for Biochemistry (RCB) and the Regensburg Center for Ultrafast Nanoscopy (RUN) as well as with external research groups.
The research groups are deciphering the origin and development of pathologically altered processes of immune cell-tissue interaction in tumor diseases and in the context of transplantation.
Starting from the analysis of the mechanisms of immune homeostasis in tissues, it will be investigated how the immunological surveillance of tissues contributes to the maintenance of their integrity and how it controls repair processes after tissue damage. UR’s researchers and their colleagues aim to find out how such immune mechanisms can be harnessed to strengthen insufficient immune control, e. g. in the development of tumors, or to suppress excessive immune responses, for instance in inflammatory diseases and after blood stem cell or organ transplants.
Highly effective and targeted immunotherapeutic approaches for cancer and transplantation medicine will be developed based on these findings. To accomplish this, scientists from the University of Regensburg’s Faculties of Medicine, Biology and Pre-clinical Medicine as well as Computer and Data Science, will cooperate closely in the CITO research building.
The already strong cooperation links with the neighboring on campus extra-university research institutes Leibniz Institute for Immuntherapy (LIT ) and Fraunhofer Group for Personalized Tumor Therapy will be even more intensified.
The scientists involved have done preliminary work for CITO in several German Research Foundation (DFG) funded (clinical) research groups (KFO 146, 243, 262 and FOR 2127, 2858), which in turn laid the foundation for the current DFG funded Collaborative Research Centers/Transregios (CRC/TRR) 221 and 305.
Further research being conducted in the focus areas of immunomedicine, transplantation and oncology is funded by the Bavarian Center for Cancer Research (BZKF), the BMBF (National Center for Tumor Diseases - NCT WERA), the EU, the German Cancer Aid (Center of Excellence in Oncology - CCC WERA), and others.
Biomolecular NMR Facility
Center for Fluorescence Imaging
Wild Plants Seed Gene Bank
RUN. Regensburg Center for Ultrafast Nanoscopy