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• "Validation strategies for antibodies targeting modified ribonucleotides", Weichmann, Hett, Schepers, Ito-Kureha, Flatley, Slama, Hastert, Angstman, Cardoso, König, Hüttelmaier, Dieterich, Canzar, Helm, Heissmeyer, Feederle, Meister, 2020

  Publication

  Chemical modifications are found on almost all RNAs and affect their coding and noncoding functions. The identification of m(6)A on mRNA and its...

  Publication on epub.uni-regensburg.de: "Validation strategies for antibodies targeting modified ribonucleotides" (external link, opens in a new window)

• "Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity", Do, Elbassioni, Canzar, 2020

  Publication

  The massive size of single-cell RNA sequencing datasets often exceeds the capability of current computational analysis methods to solve routine tasks...

  Publication on epub.uni-regensburg.de: "Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity" (external link, opens in a new window)

• "Complete sequencing of ape genomes", Yoo, Rhie, Hebbar, Antonacci, Logsdon, Solar, Antipov, Pickett, Safonova, Montinaro, Luo, Malukiewicz, Storer, Lin, Sequeira, Mangan, Hickey, Monfort Anez, Balachandran, Bankevich, Beck, Biddanda, Borchers, Bouffard, Brannan, Brooks, Carbone, Carrel, Chan, Crawford, Diekhans, Engelbrecht, Feschotte, Formenti, Garcia, de Gennaro, Gilbert, Green, Guarracino, Gupta, Haddad, Han, Harris, Hartley, Harvey, Hiller, Hoekzema, Houck, Jeong, Kamali, Kellis, Kille, Lee, Lee, Lees, Lewis, Li, Loftus, Loh, Loucks, Ma, Mao, Martinez, Masterson, McCoy, McGrath, McKinney, Meyer, Miga, Mohanty, Munson, Pal, Pennell, Pevzner, Porubsky, Potapova, Ringeling, Rocha, Ryder, Sacco, Saha, Sasaki, Schatz, Schork, Shanks, Smeds, Son, Steiner, Sweeten, Tassia, Thibaud-Nissen, Torres-González, Trivedi, Wei, Wertz, Yang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhu, Jarvis, Gerton, Rivas-González, Paten, Szpiech, Huber, Lenz, Konkel, Yi, Canzar, Watson, Sudmant, Molloy, Garrison, Lowe, Ventura, O’Neill, Koren, Makova, Phillippy, Eichler, 2025

  Publication

  The most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our...

  Publication on epub.uni-regensburg.de: "Complete sequencing of ape genomes" (external link, opens in a new window)

• "LASA: A Tool for Non-heuristic Alignment of Multiple Sequences", Althaus, Canzar, 2008

  Publication

  We have developed a non-heuristic tool (LASA) for the multiple sequence alignment problem (MSA), one of the most important problems in computational...

  Publication on epub.uni-regensburg.de: "LASA: A Tool for Non-heuristic Alignment of Multiple Sequences" (external link, opens in a new window)

• "A Lagrangian relaxation approach for the multiple sequence alignment problem", Althaus, Canzar, 2008

  Publication

  We present a branch-and-bound (bb) algorithm for the multiple sequence alignment problem (MSA), one of the most important problems in computational...

  Publication on epub.uni-regensburg.de: "A Lagrangian relaxation approach for the multiple sequence alignment problem" (external link, opens in a new window)

• "A Lagrangian Relaxation Approach for the Multiple Sequence Alignment Problem", Althaus, Canzar, 2007

  Publication

  We present a branch-and-bound (bb) algorithm for the multiple sequence alignment problem (MSA), one of the most important problems in computational...

  Publication on epub.uni-regensburg.de: "A Lagrangian Relaxation Approach for the Multiple Sequence Alignment Problem" (external link, opens in a new window)

• "Approximating the Interval Constrained Coloring Problem", Althaus, Canzar, Elbassioni, Karrenbauer, Mestre, 2008

  Publication

  We consider the interval constrained coloring problem, which appears in the interpretation of experimental data in biochemistry. Monitoring...

  Publication on epub.uni-regensburg.de: "Approximating the Interval Constrained Coloring Problem" (external link, opens in a new window)

• "CLEVER: clique-enumerating variant finder", Marschall, Costa, Canzar, Bauer, Klau, Schliep, Schönhuth, 2012

  Publication

  Motivation: Next-generation sequencing techniques have facilitated a large-scale analysis of human genetic variation. Despite the advances in...

  Publication on epub.uni-regensburg.de: "CLEVER: clique-enumerating variant finder" (external link, opens in a new window)

• "BASIC: BCR assembly from single cells", Canzar, Neu, Tang, Wilson, Khan, Hancock, 2016

  Publication

  MotivationThe B-cell receptor enables individual B cells to identify diverse antigens, including bacterial and viral proteins. While advances in...

  Publication on epub.uni-regensburg.de: "BASIC: BCR assembly from single cells" (external link, opens in a new window)

• "CAMP: Coreset Accelerated Metacell Partitioning enables scalable analysis of single-cell data", Li, Ko, Canzar, 2025

  Publication

  Scaling metacell inference to atlas-level single-cell datasets demands algorithms that are both computationally efficient and geometrically faithful....

  Publication on epub.uni-regensburg.de: "CAMP: Coreset Accelerated Metacell Partitioning enables scalable analysis of single-cell data" (external link, opens in a new window)