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• "GraphBG: Fast Bayesian Domain Detection via Spectral Graph Convolutions for Multi-slice and Multi-modal Spatial Transcriptomics", Do, Lan Tran, Canzar, 2026

  Publication

  Spatial transcriptomics (ST) technologies enable measurement of gene expression with spatial context, offering unprecedented insight into tissue...

  Publication on epub.uni-regensburg.de: "GraphBG: Fast Bayesian Domain Detection via Spectral Graph Convolutions for Multi-slice and Multi-modal Spatial Transcriptomics" (external link, opens in a new window)

• "CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders", Kim, Ringeling, Zhou, Nguyen, Temme, Lin, Eacker, Dawson, Dawson, Xiao, Hsu, Canzar, Li, Worley, Christian, Yoon, Song, Ming, 2021

  Publication

  BackgroundGene dosage imbalance caused by copy number variations (CNVs) is a prominent contributor to brain disorders. In particular, 15q11.2 CNV...

  Publication on epub.uni-regensburg.de: "CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders" (external link, opens in a new window)

• "Counting pseudoalignments to novel splicing events", Borozan, Rojas Ringeling, Kao, Nikonova, Monteagudo-Mesas, Matijević, Spletter, Canzar, Ponty, 2023

  Publication

  MotivationAlternative splicing (AS) of introns from pre-mRNA produces diverse sets of transcripts across cell types and tissues, but is also...

  Publication on epub.uni-regensburg.de: "Counting pseudoalignments to novel splicing events" (external link, opens in a new window)

• "Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy", Iyer, Moyon, Wittler, Cheng, Ringeling, Canzar, Marsico, Bulut-Karslioğlu, 2024

  Publication

  Dormancy is a key feature of stem cell function in adult tissues as well as in embryonic cells in the context of diapause. The establishment of...

  Publication on epub.uni-regensburg.de: "Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy" (external link, opens in a new window)

• "Correcting PCR amplification errors in unique molecular identifiers to generate accurate numbers of sequencing molecules", 2024

  Publication

  Unique molecular identifiers are random oligonucleotide sequences that remove PCR amplification biases. However, the impact that PCR associated...

  Publication on epub.uni-regensburg.de: "Correcting PCR amplification errors in unique molecular identifiers to generate accurate numbers of sequencing molecules" (external link, opens in a new window)

• "Anti Tai mapping for unordered labeled trees", Blažević, Canzar, Elbassioni, Matijević, 2024

  Publication

  Information Processing Letters 10.1016/j.ipl.2023.106454

  Publication on epub.uni-regensburg.de: "Anti Tai mapping for unordered labeled trees" (external link, opens in a new window)

• "Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia", Bamopoulos, Batcha, Jurinovic, Rothenberg-Thurley, Janke, Ksienzyk, Philippou-Massier, Graf, Krebs, Blum, Schneider, Konstandin, Sauerland, Görlich, Berdel, Woermann, Bohlander, Canzar, Mansmann, Hiddemann, Braess, Spiekermann, Metzeler, Herold, 2020

  Publication

  Previous studies demonstrated that splicing factor mutations are recurrent events in hematopoietic malignancies with both clinical and functional...

  Publication on epub.uni-regensburg.de: "Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia" (external link, opens in a new window)

• "Metric multidimensional scaling for large single-cell datasets using neural networks", Canzar, Do, Jelić, Laue, Matijević, Prusina, 2024

  Publication

  Metric multidimensional scaling is one of the classical methods for embedding data into low-dimensional Euclidean space. It creates the...

  Publication on epub.uni-regensburg.de: "Metric multidimensional scaling for large single-cell datasets using neural networks" (external link, opens in a new window)

• "Optimal marker genes for c-separated cell types with SepSolve", Borozan, Prusina, Borozan, Ševerdija, Rojas Ringeling, Matijević, Canzar, 2025

  Publication

  The identification of cell types in single-cell RNA-seq studies relies on the distinct expression signature of marker genes. A small set of target...

  Publication on epub.uni-regensburg.de: "Optimal marker genes for c-separated cell types with SepSolve" (external link, opens in a new window)

• "Small changes, unexpected consequences: Molecular insights into substrate-dependent adaptation of KsgA/Dim1-dependent ribosomal RNA modifications in archaea", Knüppel, 2021

  Publication

  Classically, life is divided into three phylogenetically interconnected groups of organisms, the archaea, bacteria and eukarya. However, they all...

  Publication on epub.uni-regensburg.de: "Small changes, unexpected consequences: Molecular insights into substrate-dependent adaptation of KsgA/Dim1-dependent ribosomal RNA modifications in archaea" (external link, opens in a new window)