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• "Improving enzyme functional annotation by integrating in vitro and in silico approaches: The example of histidinol phosphate phosphatases", Kinateder, Mayer, Nazet, Sterner, 2024

  Publication

  Advances in sequencing technologies have led to a rapid growth of public protein sequence databases, whereby the fraction of proteins with...

  Publication on epub.uni-regensburg.de: "Improving enzyme functional annotation by integrating in vitro and in silico approaches: The example of histidinol phosphate phosphatases" (external link, opens in a new window)

• "Conformational Modulation of a Mobile Loop Controls Catalysis in the (βα)8-Barrel Enzyme of Histidine Biosynthesis HisF", Hupfeld, Schlee, Wurm, Rajendran, Yehorova, Vos, Ravindra Raju, Kamerlin, Sprangers, Sterner, 2024

  Publication

  The overall significance of loop motions for enzymatic activity is generally accepted. However, it has largely remained unclear whether and how such...

  Publication on epub.uni-regensburg.de: "Conformational Modulation of a Mobile Loop Controls Catalysis in the (βα)8-Barrel Enzyme of Histidine Biosynthesis HisF" (external link, opens in a new window)

• "Reconstructing enzyme evolution by protein engineering", Drexler, Busch, Sterner, 2026

  Publication

  It is important to understand how the fascinating diversity of modern enzymes has manifested itself since the onset of life. A powerful approach to...

  Publication on epub.uni-regensburg.de: "Reconstructing enzyme evolution by protein engineering" (external link, opens in a new window)

• "The Discovery of N2,N2-Dimethylguanine Hydrolases Unravels General Molecular Principles of Enzyme Evolvability and Promiscuity", Drexler, Duran, Osuna, Sterner, 2026

  Publication

  The widespread use of xenobiotics has driven therapid emergence of microbial degradation pathways. A prominentexample is enzymes involved in the...

  Publication on epub.uni-regensburg.de: "The Discovery of N2,N2-Dimethylguanine Hydrolases Unravels General Molecular Principles of Enzyme Evolvability and Promiscuity" (external link, opens in a new window)

• "Photocontrolling the Enantioselectivity of a Phosphotriesterase via Incorporation of a Light-Responsive Unnatural Amino Acid", Hiefinger, Zinner, Fürtges, Narindoshvili, Schindler, Bruckmann, Rudack, Raushel, Sterner, 2025

  Publication

  The external control of catalytic activity and substrate specificity of enzymes by light has aroused great interest in the fields of biocatalysis and...

  Publication on epub.uni-regensburg.de: "Photocontrolling the Enantioselectivity of a Phosphotriesterase via Incorporation of a Light-Responsive Unnatural Amino Acid" (external link, opens in a new window)

• "A naturally occurring standalone TrpB enzyme provides insights into allosteric communication within tryptophan synthase", Kinateder, Drexler, Duran, Osuna, Sterner, 2025

  Publication

  Allosteric regulation of catalytic activity is a widespread property of multi-enzyme complexes. The tryptophan synthase is a prototypical allosteric...

  Publication on epub.uni-regensburg.de: "A naturally occurring standalone TrpB enzyme provides insights into allosteric communication within tryptophan synthase" (external link, opens in a new window)

• "On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily", Drexler, Fürtges, Rudack, Sterner, 2025

  Publication

  The sequencing of numerous genomes has led to the identification of open reading frames for millions of enzymes, many of which use unknown substrates....

  Publication on epub.uni-regensburg.de: "On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily" (external link, opens in a new window)

• "[Hierarchies in the structure and function of oxygen-binding proteins]", Decker, Sterner, 1990

  Publication

  The structures of respiratory proteins such as hemoglobins and hemocyanins show obvious hierarchies. They belong to the class of allosteric...

  Publication on epub.uni-regensburg.de: "[Hierarchies in the structure and function of oxygen-binding proteins]" (external link, opens in a new window)

• "Nested allostery of arthropodan hemocyanin (Eurypelma californicum and Homarus americanus). The role of protons.", Decker, Sterner, 1990

  Publication

  Continuous oxygen binding curves for two arthropodan hemocyanins were performed at different pH values ranging from 7.0 to 8.7 and in the presence of...

  Publication on epub.uni-regensburg.de: "Nested allostery of arthropodan hemocyanin (Eurypelma californicum and Homarus americanus). The role of protons." (external link, opens in a new window)

• "Multidimensional spline interpolation: Theory and applications", Habermann, Kindermann, 2007

  Publication

  Computing numerical solutions of household’s optimization, one often faces the problem of interpolating functions. As linear interpolation is not very...

  Publication on epub.uni-regensburg.de: "Multidimensional spline interpolation: Theory and applications" (external link, opens in a new window)