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• "Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template", Meier, Rajendran, Malisi, Fox, Xu, Schlee, Barondeau, Höcker, Sterner, Raushel, 2013

  Publication

  Rapid evolution of enzymes provides unique molecular insights into the remarkable adaptability of proteins and helps to elucidate the relationship...

  Publication on epub.uni-regensburg.de: "Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template" (external link, opens in a new window)

• "Evidence for the Existence of Elaborate Enzyme Complexes in the Paleoarchean Era", Reisinger, Sperl, Holinski, Schmid, Rajendran, Carstensen, Schlee, Blanquart, Merkl, Sterner, 2014

  Publication

  Due to the lack of macromolecular fossils, the enzymatic repertoire of extinct species has remained largely unknown to date. In an attempt to solve...

  Publication on epub.uni-regensburg.de: "Evidence for the Existence of Elaborate Enzyme Complexes in the Paleoarchean Era" (external link, opens in a new window)

• "Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors", Reisinger, Kuzmanovic, Löffler, Merkl, König, Sterner, 2014

  Publication

  The activity of the metabolic branch-point enzyme PriA from Mycobacterium tuberculosis (mtPriA) can be controlled reversibly by light. Two-pronged...

  Publication on epub.uni-regensburg.de: "Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors" (external link, opens in a new window)

• "A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization", Peterhoff, Beer, Rajendran, Kumpula, Kapetaniou, Guldan, Wierenga, Sterner, Babinger, 2014

  Publication

  Geranylgeranylglyceryl phosphate synthase (GGGPS) family enzymes catalyse the formation of an ether bond between glycerol-1-phosphate and polyprenyl...

  Publication on epub.uni-regensburg.de: "A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization" (external link, opens in a new window)

• "TrpB2 Enzymes are O-Phospho-l-serine Dependent Tryptophan Synthases", Busch, Rajendran, Mayans, Löffler, Merkl, Sterner, 2014

  Publication

  The rapid increase of the number of sequenced genomes asks for the functional annotation of the encoded enzymes. We used a combined...

  Publication on epub.uni-regensburg.de: "TrpB2 Enzymes are O-Phospho-l-serine Dependent Tryptophan Synthases" (external link, opens in a new window)

• "Activation of a chimeric Rpb5/RpoH subunit using library selection", Sommer, Waege, Pöllmann, Seitz, Thomm, Sterner, Hausner, 2014

  Publication

  Rpb5 is a general subunit of all eukaryotic RNA polymerases which consists of a N-terminal and a C-terminal domain. The corresponding archaeal subunit...

  Publication on epub.uni-regensburg.de: "Activation of a chimeric Rpb5/RpoH subunit using library selection" (external link, opens in a new window)

• "(Beta alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima.", Sterner, Dahm, Darimont, Ivens, Liebl, Kirschner, 1995

  Publication

  To better understand the evolution of a key metabolic pathway, we have sequenced the trpCFBA gene cluster of the hyperthermophilic bacterium...

  Publication on epub.uni-regensburg.de: "(Beta alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima." (external link, opens in a new window)

• "2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability.", Hennig, Darimont, Sterner, Kirschner, Jansonius, 1995

  Publication

  BACKGROUND: Recent efforts to understand the basis of protein stability have focused attention on comparative studies of proteins from...

  Publication on epub.uni-regensburg.de: "2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability." (external link, opens in a new window)

• "An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin.", Sticht, Wildegger, Bentrop, Darimont, Sterner, Rösch, 1996

  Publication

  The solution structure of the 60-residue 1[Fe4-S4] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima was determined based on 683...

  Publication on epub.uni-regensburg.de: "An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin." (external link, opens in a new window)

• "Phosphoribosyl anthranilate isomerase from Thermotoga maritima is an extremely stable and active homodimer.", Sterner, Kleemann, Szadkowski, Lustig, Hennig, Kirschner, 1996

  Publication

  The metabolism of hyperthermophilic microorganisms can function properly at temperatures close to 100 degrees C. It follows that they are equipped...

  Publication on epub.uni-regensburg.de: "Phosphoribosyl anthranilate isomerase from Thermotoga maritima is an extremely stable and active homodimer." (external link, opens in a new window)