Direkt zum Inhalt


Dr. Nina Ripin

  • Wichtige Informationen: We use interdisciplinary strategies to investigate the properties, biological functions, and disease relevance of stress-induced ribonucleoprotein (RNP) granules. Our research focuses on the role of RNA and its interactions with RNA chaperones—such as DEAD-box helicases and RNA-modifying enzymes—in shaping the integrated stress response.

Scientific Research

Our research group focuses on understanding the role of RNA, RNA condensation or aggregation and RNA Chaperones in RNP granule formation, disassembly and function. We use a combination of genome-wide, cell & molecular biology, imaging, biophysical and biochemical techniques.

Our research group was launched in April 2025. More information is coming…

We are looking for Master and PhD students. If you are interested in hearing more about available projects or in joining our group, email nina.ripin(at)ur.de.

Publications

Selected Publications

Ripin, N., Macedo De Vasconcelos, L., Ugay, D. A., & Parker, R. (2024). DDX6 modulates P-body and stress granule assembly, composition, and docking. Journal of Cell Biology, 223(6), e202306022. https://doi.org/10.1083/jcb.202306022 (externer Link, öffnet neues Fenster)

Ripin, N., & Parker, R. (2023). Formation, function, and pathology of RNP granules. Cell, 186(22), 4737–4756. https://doi.org/10.1016/j.cell.2023.09.00 (externer Link, öffnet neues Fenster)

Ripin, N., & Parker, R. (2022). Are stress granules the RNA analogs of misfolded protein aggregates? RNA, 28(1), 67–75. https://doi.org/10.1261/rna.079000.121 (externer Link, öffnet neues Fenster)

Khong, A., Ripin, N., De Vasconcelos, L. M., Spencer, S., & Parker, R. (2022). Stress granules promote chemoresistance by triggering cellular quiescence. https://doi.org/10.1101/2022.02.22.481503 (externer Link, öffnet neues Fenster)

Burke, J. M., Ripin, N., Ferretti, M. B., St Clair, L. A., Worden-Sapper, E. R., Salgado, F., Sawyer, S. L., Perera, R., Lynch, K. W., & Parker, R. (2022). RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus. PLOS Pathogens, 18(11), e1010930. https://doi.org/10.1371/journal.ppat.101093 (externer Link, öffnet neues Fenster)

Team

Dr. Nina Ripin 

Group Leader

Room Vkl 1 1.31

Tel: +(49)(0)941/943-1721

Email: nina.ripin(at)ur.de

Elena Adlmanninger

Phd Student

Room Vkl 1 1.31

Tel: +(49)(0)941/943-1721

E-mail: elena.adlmanninger(at)ur.de

Maria Schmoll

Master Student

Room Vkl 1 1.31

Tel: +(49)(0)941/943-1721

E-mail: maria.schmoll(at)ur.de

Lisa Sliwa

Bachelor Student

Room Vkl 1 1.31

Tel: +(49)(0)941/943-1721

E-mail: lisa.sliwa(at)ur.de

Adresse - Dr. Nina Ripin

nach oben