Faculty of Biology and Preclinical Medicine
The focus of our research group is the investigation of RNA-based mechanisms of gene regulation. For our research, we apply state-of-the-art techniques in biochemistry, molecular biology, and cell biology. We work with viruses and yeast, mouse, and human as model organisms.
Within the framework of research and laboratory internships as well as master’s theses, motivated students of biochemistry or biology have the opportunity to participate in scientific projects at the Chair of Biochemistry III. A detailed overview of the research conducted at the chair can be found here. Interested students should contact the office of the Chair of Biochemistry III.
In addition, we offer various compulsory and elective internships, as well as lectures and seminars for students of medicine, biochemistry, and biology.
Office hours and contact for medical and dental students
For content-related or organizational issues regarding teaching in the field of biochemistry, please contact our BC III Teaching Team. Office hours are on Wednesdays from 10:00 to 11:00 a.m.
A prior appointment and a brief description of your concern via email are required.
For general and organizational questions, the program coordinator, Ms. Stefanie Goldhacker, will be happy to provide information.
Courses (Chair of Biochemistry III)
General courses
54252
Analysis of NextGen Sequencing Data in Galaxy (external link, opens in a new window)
54065
54180c
54182 A
Biochemisches Großpraktikum II Teil A (Molekularbiologie) (external link, opens in a new window)
54070
Biochemisches Praktikum (external link, opens in a new window)
54071
Biochemisches Seminar (external link, opens in a new window)
54183
Biochemisches Seminar II (external link, opens in a new window)
Essay: Biochemie (Ribosomengenese) (external link, opens in a new window)
54221
Gestaltung und Präsentation eines Posters (external link, opens in a new window)
54251
Lab course: Analysis of next-generation-sequencing data (external link, opens in a new window)
54192
Laborpraktikum: Biochemie (Ribosomengenese) (external link, opens in a new window)
54208
Literaturseminar: RNA-Biologie (external link, opens in a new window)
54253
NGS Analysis Club (external link, opens in a new window)
Poster: Biochemie (Ribosomengenese) (external link, opens in a new window)
Projektskizze der Masterarbeit (external link, opens in a new window)
54214
Seminar: Biochemie (Transcription and Chromatin) (external link, opens in a new window)
Seminarvortrag zur Bachelorarbeit BSc Biologie (external link, opens in a new window)
54207
Spezialvorlesung: RNA-Biology (external link, opens in a new window)
Courses for medical and dental students
Course 43065/54066: Lecture ‘Biochemistry for medical and dental students A and B’
Course 54070/54071: Biochemistry practical course and seminar for medical and dental students
All dates and other materials relevant to the laboratory course will be made available on the notice board at the Institute of Biochemistry III and in a GRIPS course. Enrollment in the course is password-protected. The link to the GRIPS course and the password will be sent to participants by email.
Courses for biochemistry students
Course 54182A: Advanced Biochemistry practical course II Part A for Biochemistry Students
The concept of this practical course is to work on several research questions within the framework of a coherent project, similar to a scientific laboratory setting. A variety of methods are employed, with a focus on molecular biology applications. These are complemented by genetic and cell biological techniques, as well as bioinformatic analyses. The goal is to provide an impression of modern methodology to obtain any protein constructively and efficiently by combining these different techniques. The baker’s yeast Saccharomyces cerevisiae serves as model organism. It is well-suited for biochemical, genetic, and cell biological experiments, and extensive genome-wide data are available for this organism.
Methods:
In E. coli: Cloning and expression of recombinant proteins. Detection via SDS-PAGE.
In S. cerevisiae: Genetic manipulation and expression of recombinant proteins. Detection via SDS-PAGE and Western blot. Affinity purification and enzymatic analysis of recombinant fusion proteins. Isolation of genomic DNA. Detection of genetic modifications via Southern blot and determination of relative and absolute nucleic acid quantities by quantitative PCR.
Additional Information:
The laboratory course takes place at the beginning of the summer semester. Participants can also enroll in a GRIPS course, where all laboratory-relevant materials are provided. Enrollment in the course is password-protected. The link to the GRIPS course and the password will be sent to participants by email.
Courses for biology students
Course 54232: Molecular biology project-based practical course supported by a seminar
The concept of this laboratory course is to work on several research questions within the framework of a coherent project, similar to a scientific laboratory setting. A variety of methods are employed, with a focus on molecular biology and biochemical applications. These are complemented by modern genetic and cell biological techniques, as well as bioinformatic analyses. The goal is to provide an impression of how, today, important insights into any protein can be obtained constructively and efficiently by combining these different techniques. The baker’s yeast Saccharomyces cerevisiae serves as an ideal model organism. It is equally well-suited for biochemical, genetic, and cell biological experiments, and extensive additional information is available from numerous genome-wide analyses.
Methods:
In E. coli: Cloning, expression of recombinant proteins, and detection via SDS-PAGE.
In S. cerevisiae: Genetic manipulation and expression of recombinant proteins and their purification, determination of enzymatic activity, isolation of genomic DNA, as well as relative and absolute quantification of nucleic acids using quantitative PCR.
Additional Information:
The laboratory course takes place during the winter semester in November/December.
Participants can enroll in a GRIPS course, where all laboratory-relevant materials are provided. Enrollment in the course is password-protected. The link to the GRIPS course and the password will be sent to participants by email.