New members for the Caliskan team!
We are happy to welcome Eva-Maria Lederer and Dr. Andreas Maier, both from TU Munich, to our team.
They will support us with their expertise, among other things, in further developing ribosome profiling and protein expression at the chair.
Here’s to a successful 2026!
The basics of HIV research at the group of Prof. Dr. Neva Caliskan
A recent study has shed light on how HIV-1, the virus responsible for AIDS, hijacks the cellular machinery for its own survival. By analyzing the molecular interplay between the virus and its host, researchers identified new strategies of HIV-1 to ensure its replication while simultaneously suppressing the host’s cellular defenses (published in Nature Structural and Molecular Biology).
Like other viruses, HIV-1 is unable to produce its own proteins and must rely on the host cell to translate its genetic instructions. After entering the host cell, it takes control of the translation process in which messenger ribonucleic acid (mRNA) is converted into proteins. “In this study, we combined ribosome profiling, RNA sequencing, and RNA structure probing to map the viral and host translation landscape and the ribosomal stalling during viral replication in unprecedented detail,” says corresponding author Neva Caliskan, who holds the Chair of Biochemistry III at the University of Regensburg.