A complete list of publications can be found here
Preprints
Manuscripts with a special focus
- Glanzlicht biomedizinischer Forschung
Information can be found HERE
Triebelhorn, J., Cardon, I., Kuffner, K. et al. Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties. Mol Psychiatry 29, 1217–1227 (2024). doi.org/10.1038/s41380-022-01660-1 - Glanzlicht biomedizinischer Forschung
Information can be fouund HERE
Cardon, I., Grobecker, S., Jenne, F. et al. Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression. Mol Psychiatry 29, 2689–2700 (2024). doi.org/10.1038/s41380-024-02538-0
Selected Publications
Issa R, Wein S, Milenkovic VM, Rupprecht R, Wetzel CH, Schwarzbach JV (2026) From Cell to Circuit: Altered Functional Network Topology in iPSC-derived Neuronal Circuits in Major Depressive Disorder. Neuroimage:122309. 10.1016/j.neuroimage.2026.122309
Cardon I, Grobecker S, Jenne F, Jahner T, Rupprecht R, Milenkovic VM, Wetzel CH (2024) Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression. Mol Psychiatry 29:2689–2700. 10.1038/s41380-024-02538-0
Cardon I, Grobecker S, Kucukoktay S, Bader S, Jahner T, Nothdurfter C, Koschitzki K, Berneburg M, Weber BHF, Stohr H, Horing M, Liebisch G, Braun F, Rothammer-Hampl T, Riemenschneider MJ, Rupprecht R, Milenkovic VM, Wetzel CH (2024) Mitochondrial and Cellular Function in Fibroblasts, Induced Neurons, and Astrocytes Derived from Case Study Patients: Insights into Major Depression as a Mitochondria-Associated Disease. Int J Mol Sci 25:963. 10.3390/ijms25020963
Bader S, Jahner T, Dorfelt A, Melchner D, Cardon I, Siegmund HI, Brochhausen C, Rupprecht R, Milenkovic VM, Wetzel CH (2024) A comprehensive functional investigation of the human translocator protein 18 kDa (TSPO) in a novel human neuronal cell knockout model. Int J Mol Sci 25:12882. 10.3390/ijms252312882
Bader S, Wurfel T, Jahner T, Nothdurfter C, Rupprecht R, Milenkovic VM, Wetzel CH (2023) Impact of translocator protein 18 kDa (TSPO) deficiency on mitochondrial function and the inflammatory state of human C20 microglia cells. Cells 12. 10.3390/cells12060954
Rupprecht R, Wetzel CH, Dorostkar M, Herms J, Albert NL, Schwarzbach J, Schumacher M, Neumann ID (2022) Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders? Mol Psychiatry 27:2918–2926. 10.1038/s41380-022-01561-3
Triebelhorn J, Cardon I, Kuffner K, Bader S, Jahner T, Meindl K, Rothhammer-Hampl T, Riemenschneider MJ, Drexler K, Berneburg M, Nothdurfter C, Manook A, Brochhausen C, Baghai TC, Hilbert S, Rupprecht R, Milenkovic VM, Wetzel CH (2022) Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties. Mol Psychiatry 29:1217–1227. 10.1038/s41380-022-01660-1
Kuffner K, Triebelhorn J, Meindl K, Benner C, Manook A, Sudria-Lopez D, Siebert R, Nothdurfter C, Baghai TC, Drexler K, Berneburg M, Rupprecht R, Milenkovic VM, Wetzel CH (2020) Major depressive disorder is associated with impaired mitochondrial function in skin fibroblasts. Cells 9:884. 10.3390/cells9040884