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• "Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site", List, Vega, Razeto, Häger, Sterner, Wilmanns, 2012

  Publikation

  Nitrogen is incorporated into various metabolites by multifunctional glutamine amidotransferases via reactive ammonia generated by glutaminase...

  Publikation auf epub.uni-regensburg.de: "Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site" (externer Link, öffnet neues Fenster)

• "Constitutively Active Glutaminase Variants Provide Insights into the Activation Mechanism of Anthranilate Synthase", List, Bocola, Haeger, Sterner, 2012

  Publikation

  The glutamine amidotransferase (GATase) family comprises enzyme complexes which consist of glutaminase and synthase subunits that catalyze in a...

  Publikation auf epub.uni-regensburg.de: "Constitutively Active Glutaminase Variants Provide Insights into the Activation Mechanism of Anthranilate Synthase" (externer Link, öffnet neues Fenster)

• "Directed evolution of ( )8-barrel enzymes: establishing phosphoribosylanthranilate isomerisation activity on the scaffold of the tryptophan synthase -subunit", Evran, Telefoncu, Sterner, 2012

  Publikation

  Phosphoribosylanthranilate (PRA) isomerase (TrpF) and tryptophan synthase -subunit (TrpA) are ()(8)-barrel enzymes that are involved in the...

  Publikation auf epub.uni-regensburg.de: "Directed evolution of ( )8-barrel enzymes: establishing phosphoribosylanthranilate isomerisation activity on the scaffold of the tryptophan synthase -subunit" (externer Link, öffnet neues Fenster)

• "Random mutagenesis suggests that sequence errors are not a major cause of variation in the activity of individual molecules of β-galactosidase", Craig, Schwab, Sterner, 2012

  Publikation

  Wild-type Escherichia coli lacZ was subjected to error-prone PCR to generate two plasmid-encoded gene libraries containing approximately 2.6 (SD 1.9)...

  Publikation auf epub.uni-regensburg.de: "Random mutagenesis suggests that sequence errors are not a major cause of variation in the activity of individual molecules of β-galactosidase" (externer Link, öffnet neues Fenster)

• "Folding Mechanism of an Extremely Thermostable (βα)8-Barrel Enzyme: A High Kinetic Barrier Protects the Protein from Denaturation", Carstensen, Zoldák, Schmid, Sterner, 2012

  Publikation

  HisF, the cyclase subunit of imidazole glycerol phosphate synthase (ImGPS) from Thermotoga maritima, is an extremely thermostable (beta...

  Publikation auf epub.uni-regensburg.de: "Folding Mechanism of an Extremely Thermostable (βα)8-Barrel Enzyme: A High Kinetic Barrier Protects the Protein from Denaturation" (externer Link, öffnet neues Fenster)

• "Conservation of the Folding Mechanism between Designed Primordial (βα)8-Barrel Proteins and Their Modern Descendant", Carstensen, Sperl, Bocola, List, Schmid, Sterner, 2012

  Publikation

  The (beta alpha)(8)-barrel is among the most ancient, frequent, and versatile enzyme structures. It was proposed that modern (beta alpha)(8)-barrel...

  Publikation auf epub.uni-regensburg.de: "Conservation of the Folding Mechanism between Designed Primordial (βα)8-Barrel Proteins and Their Modern Descendant" (externer Link, öffnet neues Fenster)

• "Experimental assessment of the importance of amino acid positions identified by an entropy-based correlation analysis of multiple sequence alignments", Dietrich, Borst, Schlee, Schneider, Janda, Sterner, Merkl, 2012

  Publikation

  The analysis of a multiple-sequence alignment (MSA) with correlation methods identifies pairs of residue positions whose occupation with amino acids...

  Publikation auf epub.uni-regensburg.de: "Experimental assessment of the importance of amino acid positions identified by an entropy-based correlation analysis of multiple sequence alignments" (externer Link, öffnet neues Fenster)

• "Establishing catalytic activity on an artificial (βα)8‐barrel protein designed from identical half‐barrels", Sperl, Rohweder, Rajendran, Sterner, 2013

  Publikation

  It has been postulated that the ubiquitous (beta alpha)(8)-barrel enzyme fold has evolved by duplication and fusion of an ancestral (beta...

  Publikation auf epub.uni-regensburg.de: "Establishing catalytic activity on an artificial (βα)8‐barrel protein designed from identical half‐barrels" (externer Link, öffnet neues Fenster)

• "Nested allostery of arthropodan hemocyanin (Eurypelma californicum and Homarus americanus). The role of protons.", Decker, Sterner, 1990

  Publikation

  Continuous oxygen binding curves for two arthropodan hemocyanins were performed at different pH values ranging from 7.0 to 8.7 and in the presence of...

  Publikation auf epub.uni-regensburg.de: "Nested allostery of arthropodan hemocyanin (Eurypelma californicum and Homarus americanus). The role of protons." (externer Link, öffnet neues Fenster)

• "Inversion of the Bohr effect upon oxygen binding to 24-meric tarantula hemocyanin.", Sterner, Decker, 1994

  Publikation

  The Bohr effect describes the usually negative coupling between the binding of oxygen and the binding of protons to respiratory proteins. It was first...

  Publikation auf epub.uni-regensburg.de: "Inversion of the Bohr effect upon oxygen binding to 24-meric tarantula hemocyanin." (externer Link, öffnet neues Fenster)