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• "Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds", Claren, Malisi, Höcker, Sterner, 2009

  Publikation

  The generation of high levels of new catalytic activities on natural and artificial protein scaffolds is a major goal of enzyme engineering. Here, we...

  Publikation auf epub.uni-regensburg.de: "Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds" (externer Link, öffnet neues Fenster)

• "Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening", Seitz, Thoma, Schoch, Stihle, Benz, D'Arcy, Wiget, Ruf, Hennig, Sterner, 2010

  Publikation

  The human glucocorticoid receptor ligand-binding domain (hGR-LBD) is an important drug target for the treatment of various diseases. However, the low...

  Publikation auf epub.uni-regensburg.de: "Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening" (externer Link, öffnet neues Fenster)

• "Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds", Richter, Bosnali, Carstensen, Seitz, Durchschlag, Blanquart, Merkl, Sterner, 2010

  Publikation

  The evolution of the prototypical (beta alpha)(8)-barrel protein imidazole glycerol phosphate synthase (HisF) was studied by complementary...

  Publikation auf epub.uni-regensburg.de: "Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds" (externer Link, öffnet neues Fenster)

• "The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy", Liebold, List, Kalbitzer, Sterner, Brunner, 2010

  Publikation

  The imidazole glycerol phosphate (ImGP) synthase from the hyperthermophilic bacterium Thermotoga maritima is a 1:1 complex of the glutaminase subunit...

  Publikation auf epub.uni-regensburg.de: "The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy" (externer Link, öffnet neues Fenster)

• "Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry", Ehrmann, Richter, Busch, Reimann, Albers, Sterner, 2010

  Publikation

  The prototypical tryptophan synthases form a stable heterotetrameric alpha beta beta alpha complex in which the constituting TrpA and TrpB1 subunits...

  Publikation auf epub.uni-regensburg.de: "Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry" (externer Link, öffnet neues Fenster)

• "Hyperthermostable acetyl xylan esterase", Drzewiecki, Angelov, Ballschmiter, Tiefenbach, Sterner, Liebl, 2010

  Publikation

  An esterase which is encoded within a Thermotoga maritima chromosomal gene cluster for xylan degradation and utilization was characterized after...

  Publikation auf epub.uni-regensburg.de: "Hyperthermostable acetyl xylan esterase" (externer Link, öffnet neues Fenster)

• "Computational and Experimental Evidence for the Evolution of a (betaalpha)(8)-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds", Richter, Bosnali, Carstensen, Seitz, Durchschlag, Blanquart, Merkl, Sterner, 2010

  Publikation

  The evolution of the prototypical (beta alpha)(8)-barrel protein imidazole glycerol phosphate synthase (HisF) was studied by complementary...

  Publikation auf epub.uni-regensburg.de: "Computational and Experimental Evidence for the Evolution of a (betaalpha)(8)-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds" (externer Link, öffnet neues Fenster)

• "Stabilization of a Metabolic Enzyme by Library Selection in Thermus thermophilus", Schwab, Sterner, 2011

  Publikation

  The anthranilate phosphoribosyl transferase from the hyper-thermophilic archaeon Sulfolobus solfataricus (sAnPRT, encoded by strpD), which catalyzes...

  Publikation auf epub.uni-regensburg.de: "Stabilization of a Metabolic Enzyme by Library Selection in Thermus thermophilus" (externer Link, öffnet neues Fenster)

• "Related (βα)8‐Barrel Proteins in Histidine and Tryptophan Biosynthesis: A Paradigm to Study Enzyme Evolution", List, Sterner, Wilmanns, 2011

  Publikation

  ChemBioChem 1439-4227,1439-4227 10.1002/cbic.201100082

  Publikation auf epub.uni-regensburg.de: "Related (βα)8‐Barrel Proteins in Histidine and Tryptophan Biosynthesis: A Paradigm to Study Enzyme Evolution" (externer Link, öffnet neues Fenster)

• "Functional Assignment of an Enzyme that Catalyzes the Synthesis of an Archaea-Type Ether Lipid in Bacteria", Guldan, Matysik, Bocola, Sterner, Babinger, 2011

  Publikation

  Angewandte Chemie International Edition 10.1002/anie.201101832

  Publikation auf epub.uni-regensburg.de: "Functional Assignment of an Enzyme that Catalyzes the Synthesis of an Archaea-Type Ether Lipid in Bacteria" (externer Link, öffnet neues Fenster)