Suche

Suchergebnisse

• "A histidine gene cluster of the hyperthermophile Thermotoga maritima: sequence analysis and evolutionary significance.", Thoma, Schwander, Liebl, Kirschner, Sterner, 1998

  Publikation

  The sequences of histidine operon genes in hyperthermophiles are informative for understanding high protein thermostability and the evolution of...

  Publikation auf epub.uni-regensburg.de: "A histidine gene cluster of the hyperthermophile Thermotoga maritima: sequence analysis and evolutionary significance." (externer Link, öffnet neues Fenster)

• "Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis.", Thoma, Obmolova, Lang, Schwander, Jenö, Sterner, Wilmanns, 1999

  Publikation

  Enzymes from hyperthermophiles can be efficiently purified after expression in mesophilic hosts and are well-suited for crystallisation attempts. Two...

  Publikation auf epub.uni-regensburg.de: "Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis." (externer Link, öffnet neues Fenster)

• "Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima.", Thoma, Hennig, Sterner, Kirschner, 2000

  Publikation

  BACKGROUND: Oligomeric proteins may have been selected for in hyperthermophiles because subunit association provides extra stabilization....

  Publikation auf epub.uni-regensburg.de: "Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima." (externer Link, öffnet neues Fenster)

• "Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion.", Lang, Thoma, Henn-Sax, Sterner, Wilmanns, 2000

  Publikation

  The atomic structures of two proteins in the histidine biosynthesis pathway consist of beta/alpha barrels with a twofold repeat pattern. It is likely...

  Publikation auf epub.uni-regensburg.de: "Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion." (externer Link, öffnet neues Fenster)

• "Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways.", Jürgens, Strom, Wegener, Hettwer, Wilmanns, Sterner, 2000

  Publikation

  Enzymes participating in different metabolic pathways often have similar catalytic mechanisms and structures, suggesting their evolution from a common...

  Publikation auf epub.uni-regensburg.de: "Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways." (externer Link, öffnet neues Fenster)

• "Phosphoribosylanthranilate isomerase and indoleglycerol-phosphate synthase: tryptophan biosynthetic enzymes from Thermotoga maritima.", Sterner, Merz, Thoma, Kirschner, 2001

  Publikation

  Methods in enzymology

  Publikation auf epub.uni-regensburg.de: "Phosphoribosylanthranilate isomerase and indoleglycerol-phosphate synthase: tryptophan biosynthetic enzymes from Thermotoga maritima." (externer Link, öffnet neues Fenster)

• "Thermophilic adaptation of proteins.", Sterner, Liebl, 2001

  Publikation

  Hyperthermophilic organisms optimally grow close to the boiling point of water. As a consequence, their macromolecules must be much more thermostable...

  Publikation auf epub.uni-regensburg.de: "Thermophilic adaptation of proteins." (externer Link, öffnet neues Fenster)

• "Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex.", Douangamath, Walker, Beismann-Driemeyer, Vega-Fernandez, Sterner, Wilmanns, 2002

  Publikation

  Since reactive ammonia is not available under physiological conditions, glutamine is used as a source for the incorporation of nitrogen in a number of...

  Publikation auf epub.uni-regensburg.de: "Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex." (externer Link, öffnet neues Fenster)

• "Protein design at the crossroads of biotechnology, chemistry, theory, and evolution.", Jaenicke, Sterner, 2003

  Publikation

  Angewandte Chemie (International ed. in English) 10.1002/anie.200390068

  Publikation auf epub.uni-regensburg.de: "Protein design at the crossroads of biotechnology, chemistry, theory, and evolution." (externer Link, öffnet neues Fenster)

• "Characterisation of a thermoalkali-stable cyclodextrin glycosyltransferase from the anaerobic thermoalkaliphilic bacterium Anaerobranca gottschalkii.", Thiemann, Dönges, Prowe, Sterner, Antranikian, 2004

  Publikation

  The thermoalkaliphilic anaerobic bacterium Anaerobranca gottschalkii produces an extracellular CGTase when grown on starch at 55 degrees C and pH 9.0....

  Publikation auf epub.uni-regensburg.de: "Characterisation of a thermoalkali-stable cyclodextrin glycosyltransferase from the anaerobic thermoalkaliphilic bacterium Anaerobranca gottschalkii." (externer Link, öffnet neues Fenster)