Bioinformatics

Organising working group: Prof. Till Rudack

Theory Module - Bioinformatics

BIO-M-TM-BI

Module contents
Bioinformatics algorithms related to biological structures and sequences, modeling of biological structures, analysis of large data sets, fundamentals of machine learning Presentation and discussion of a research-based bioinformatics topic based on common literature

No.	Module component	CP	registration / proof of academic achievement
1.	at least two lectures in the field of bioinformatics* Possible courses to choose from include: 54260: Molecular Modeling for Beginners (link SPUR) 54265: Introduction to Molecular Modeling (link SPUR) 54266: Drug Discovery: Introduction and Computer-Aided Applications (link SPUR) 54254: Introduction to the Structural Biology of Macromolecular Machines: From Cryo-EM to Molecular Dynamics Simulation (link SPUR) Details on all courses can be found in SPUR. Additional bioinformatics courses may be accepted upon review by the module coordinator. (A current overview of all available courses can be found on the Structural Bioinformatics teaching website)	6	Students starting before the winter semester 26/27: Registration is not required for the lectures. There is no exam to sit. However, the content of the lectures may form part of the oral exam. Students starting in the winter semester 26/27 or later: Portfolio (collection of exercises and reflective tasks completed alongside the lectures). Please ask the module coordinator about the requirements. Once it has been finalised, the portfolio must be registered in FlexNow. The portfolio is not graded.
2.	one seminar in the field of bioinformatics* Possible seminars to choose from include: 54261: Methods and Applications of Structural Bioinformatics (link SPUR) 54262: Seminar on Current Research in Structural Bioinformatics (link SPUR) Details on all seminars can be found in SPUR. Additional bioinformatics seminars may be accepted upon review by the module coordinator. (A current overview of all offerings can be found on the Structural Bioinformatics teaching website)	2	seminar presentation, regular participation You must register for the seminars. Information on how to register see in SPUR. Once you have attended a seminar, it must be registered in FlexNow. The seminar is not graded.
3.	30 min oral examination covering the entire module (graded)	4	Examiners: Prof. Till Rudack (Structural Bioinformatics) Prof. Wolfram Gronwald (externer Link, öffnet neues Fenster) (NMR Spectroscopy) Prof. Dr. Rainer Spang (externer Link, öffnet neues Fenster) (Statistical Bioinformatics) Prof. Dr. Canzar (externer Link, öffnet neues Fenster) (Algorithmic Bioinformatics) The student can choose one of the examiner. Please get in contact with the examiner of your choice to arrange a date of the oral examination, than register the examination in FlexNow. The oral examination is graded (= module grade).

*Note! If you are unsure which lectures and seminars to choose, please contact the module coordinator for advice. Your choice may depend on which examiner you select for the module examination.

Module download:

For students starting before the winter semester 26/27: BIO-M-TM-BI (pdf) (öffnet neues Fenster). (nicht barrierefrei)

For students starting in the winter semester 26/27 or later: BIO-M-TM-BI (pdf) (öffnet neues Fenster). (nicht barrierefrei)

Practical Module - Sequence- and Structure-based Computational Biology

BIO-M-PM-BI

Module coordinator: Prof. Till Rudack (externer Link, öffnet neues Fenster)

Module contents
visualization and analysis of protein 3D structures, structure prediction using artificial intelligence, homology modeling, protein design, molecular dynamics simulations, integrative structural biology modeling strategies, quantum chemical and quantum biological calculations, sequence comparison, initial programming experience with Python, presentation and discussion of one’s own discoveries based on bioinformatics findings

Module component	CP	proof of academic achievement
Laboratory course (6 weeks): Sequence- and structure based bioinformatics (54246; link SPUR (externer Link, öffnet neues Fenster)) Contact the module coordinator to find a supervisor for the laboratory course. The date of the laboratory course will then be arranged with the supervisor. Laboratory courses are acceptet from following groups: Prof. Till Rudack (Structural Bioinformatics) Prof. Wolfram Gronwald (externer Link, öffnet neues Fenster) (NMR Spectroscopy) Prof. Dr. Rainer Spang (externer Link, öffnet neues Fenster) (Statistical Bioinformatics) Prof. Dr. Canzar (externer Link, öffnet neues Fenster) (Algorithmic Bioinformatics) For more information contact Prof. Till Rudack	12	Portfolio (graded)*

*The portfolio examination contains following:

Internship report of 4.000–10.000 words, including a bibliography,
scientific presentation (15-30 min),
practical scientific work,
data, protocols, and records -including electronic data- from scientific work, prepared in accordance with the principles of good scientific practice.

The grade of the portfolio is based on the evaluation of the report, the presentation, and the practical work in the lab. The supervisor of the laboratory course can use a template for the evaluation - Evaluation of a practical module - PDF (externer Link, öffnet neues Fenster).
The completed evaluation should then be given to the student as feedback.

Module download:

For students starting before the winter semester 26/27: BIO-M-PM-CB (pdf) (öffnet neues Fenster). (nicht barrierefrei)

For students starting in the winter semester 26/27 or later: BIO-M-PM-BI (pdf) (öffnet neues Fenster). (nicht barrierefrei)

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