Immunology

Teaching Coordinator: Prof. Dr. Uwe Ritter

Link to the Leibniz Institute for Immunotherapy (externer Link, öffnet neues Fenster)

If interested please send an e-mail by September 30th each year for the upcoming winter term to: Prof. Dr. Uwe Ritter (T. 944-18125, uwe.ritter@lit.eu).

Theory Module - Immunology

BIO-M-TM-I

Teaching Coordinator: Prof. Dr. Uwe Ritter

(link to LIT research group (externer Link, öffnet neues Fenster))

Module contents
- Fundamentals of Immunology 1. Fundamentals of the innate immune systemPhysical/chemical barriers (skin, mucous membranes, secretions) Complement system (opsonization, lysis, promotion of inflammation) Cytokines (pro- and anti-inflammatory mediators) Cellular components (neutrophils, macrophages, NK cells, dendritic cells) Rapid, nonspecific first line of defense2. 2. Fundamentals of the adaptive immune response Antigen presentation (APC, MHC I/MHC II) T cell activation and differentiation (CD4/CD8; Th1/Th2/Th17/Treg) Development of T cells in the thymus Development of B cells in the bone marrow B cell activation (T cell-dependent/independent, affinity maturation, class switching) Secondary lymphoid organs (lymph nodes, spleen, Peyer’s patches) Cell migration and homing (chemokines, adhesion molecules) 3. Dysfunctions of the Immune Response Allergies (hypersensitivity reactions) Autoimmunity (self-reaction against body substances) Transplant rejection Immunodeficiencies or chronic inflammation 4. Fundamentals of immunotherapy CAR T cells (genetically modified T cells targeting tumor antigens) Checkpoint inhibitors (blockade of CTLA-4/PD-1/PD-L1 to reactivate T cells) - Advanced Immunology Tumor Immunology (Advanced) Allergies and Autoimmune Diseases (Advanced) Immunotherapy (Advanced) - Seminar: Milestones in Immunology Presentation and discussion of research topics in the field of Immunology

No.	Module component	CP	registration / proof of academic achievement
1.	Lectures: Basic Immunology (56151, link SPUR (externer Link, öffnet neues Fenster)) Advanced Immunology (56152, link SPUR (externer Link, öffnet neues Fenster))	6	Students starting before the winter semester 26/27: Registration is not required for the lectures. There is no exam to sit. However, the content of the lectures may form part of the oral exam. Students starting in the winter semester 26/27 or later: Portfolio (collection of exercises and reflective tasks completed alongside the lectures). Please ask the module coordinator about the requirements. Once it has been finalised, the portfolio must be registered in FlexNow. The portfolio is not graded.
2.	Seminar: Milestones in Immunology (56163, link SPUR (externer Link, öffnet neues Fenster))	2	seminar presentation, regular participation You must register for the seminars. Information on how to register see in SPUR. Once you have attended a seminar, it must be registered in FlexNow. The seminar is not graded.
3.	30 min oral examination covering the entire module (graded)	4	Examiner: Prof. Dr. Uwe Ritter Please get in contact with the examiner to arrange a date of the oral examination, than register the examination in FlexNow. The oral examination is graded (= module grade).

Module download pdf

For students starting before the winter semester 26/27: BIO-M-TM-I (pdf) (öffnet neues Fenster). (nicht barrierefrei)

For students starting in the winter semester 26/27 or later: BIO-M-TM-I (pdf) (öffnet neues Fenster). (nicht barrierefrei)

Practical Module - Immunology

BIO-M-PM-I

Teaching Coordinator: Prof. Dr. Uwe Ritter (link to LIT research group (externer Link, öffnet neues Fenster))

Module contents
During the laboratory course „State of the Art“ technologies relevant in modern Immunology will be acquired. The laboratory course can be completed in one of the working groups within the Leibnitz Institute of Immunotherapy and should be finished by the end of the following summer semester. Presentation and discussion of own experimental gained data

Module component	CP	proof of academic achievement
Laboratory course (6 weeks): Immunology (Nr. 54171, link SPUR (externer Link, öffnet neues Fenster)) Contact the module coordinator to find a supervisor for the laboratory course. The date of the laboratory course will then be arranged with the supervisor.	12	Portfolio (graded)*

*The portfolio examination contains following:

Internship report of 4.000–10.000 words, including a bibliography,
scientific presentation (15-30 min),
practical scientific work,
data, protocols, and records -including electronic data- from scientific work, prepared in accordance with the principles of good scientific practice.

The grade of the portfolio is based on the evaluation of the report, the presentation, and the practical work in the lab. The supervisor of the laboratory course can use a template for the evaluation - Evaluation of a practical module - PDF (externer Link, öffnet neues Fenster)

The completed evaluation should then be given to the student as feedback.

Module download pdf

For students starting before the winter semester 26/27: BIO-M-PM-I (pdf) (öffnet neues Fenster). (nicht barrierefrei)

For students starting in the winter semester 26/27 or later: BIO-M-PM-I (pdf) (öffnet neues Fenster). (nicht barrierefrei)

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