Suche

Suchergebnisse

• "Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation", Merkl, Plach, Reisinger, Sterner, 2016

  Publikation

  Modern enzymes are highly optimized biocatalysts that process their substrates with extreme efficiency. Many enzymes catalyze more than one reaction;...

  Publikation auf epub.uni-regensburg.de: "Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation" (externer Link, öffnet neues Fenster)

• "Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia", Ruther, Hagström, Brandstetter, Hofferberth, Bruckmann, Semmelmann, Fink, Lowack, Laberer, Niehuis, Deutzmann, Löfstedt, Sterner, 2016

  Publikation

  Males of all species of the parasitic wasp genus Nasonia use (4R,5S)-5-hydroxy-4-decanolide (RS) as component of their sex pheromone while only N....

  Publikation auf epub.uni-regensburg.de: "Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia" (externer Link, öffnet neues Fenster)

• "Highlight issue: protein design", Sterner, Höcker, Kolmar, 2017

  Publikation

  Biological Chemistry 1431-6730,1437-4315 10.1515/hsz-2016-0322

  Publikation auf epub.uni-regensburg.de: "Highlight issue: protein design" (externer Link, öffnet neues Fenster)

• "Photochromic Coenzyme Q Derivatives: Switching Redox Potentials with Light", Simeth, Kneuttinger, Sterner, König, 2017

  Publikation

  Coenzyme Q is an important redox cofactor involved in a variety of cellular processes, and thus found in several cell compartments. We report a...

  Publikation auf epub.uni-regensburg.de: "Photochromic Coenzyme Q Derivatives: Switching Redox Potentials with Light" (externer Link, öffnet neues Fenster)

• "Evolutionary diversification of protein–protein interactions by interface add-ons", Plach, Semmelmann, Busch, Busch, Heizinger, Wysocki, Merkl, Sterner, 2017

  Publikation

  Cells contain amultitude of protein complexes whose subunits interact with high specificity. However, the number of different protein folds and...

  Publikation auf epub.uni-regensburg.de: "Evolutionary diversification of protein–protein interactions by interface add-ons" (externer Link, öffnet neues Fenster)

• "Combining ancestral sequence reconstruction with protein design to identify an interface hotspot in a key metabolic enzyme complex", Holinski, Heyn, Merkl, Sterner, 2017

  Publikation

  It is important to identify hotspot residues that determine protein-protein interactions in interfaces of macromolecular complexes. We have applied a...

  Publikation auf epub.uni-regensburg.de: "Combining ancestral sequence reconstruction with protein design to identify an interface hotspot in a key metabolic enzyme complex" (externer Link, öffnet neues Fenster)

• "Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island", Antranikian, Suleiman, Schäfers, Adams, Bartolucci, Blamey, Birkeland, Bonch-Osmolovskaya, da Costa, Cowan, Danson, Forterre, Kelly, Ishino, Littlechild, Moracci, Noll, Oshima, Robb, Rossi, Santos, Schönheit, Sterner, Thauer, Thomm, Wiegel, Stetter, 2017

  Publikation

  To obtain new insights into community compositions of hyperthermophilic microorganisms, defined as having optimal growth temperatures of 80 degrees C...

  Publikation auf epub.uni-regensburg.de: "Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island" (externer Link, öffnet neues Fenster)

• "Rosetta:MSF: a modular framework for multi-state computational protein design", Merkl, Löffler, Schmitz, Hupfeld, Sterner, 2017

  Publikation

  Computational protein design (CPD) is a powerful technique to engineer existing proteins or to design novel ones that display desired properties....

  Publikation auf epub.uni-regensburg.de: "Rosetta:MSF: a modular framework for multi-state computational protein design" (externer Link, öffnet neues Fenster)

• "Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase", Schlee, Klein, Schumacher, Nazet, Merkl, Steinhoff, Sterner, 2018

  Publikation

  It is important to understand how the catalytic activity of enzymes is related to their conformational flexibility. We have studied this...

  Publikation auf epub.uni-regensburg.de: "Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase" (externer Link, öffnet neues Fenster)

• "Hexamerization of Geranylgeranylglyceryl Phosphate Synthase Ensures Structural Integrity and Catalytic Activity at High Temperatures", Linde, Heyn, Merkl, Sterner, Babinger, 2018

  Publikation

  The cell membranes of all archaea contain ether lipids, and a number of archaea are hyperthermophilic. Consequently, the enzymes that catalyze the...

  Publikation auf epub.uni-regensburg.de: "Hexamerization of Geranylgeranylglyceryl Phosphate Synthase Ensures Structural Integrity and Catalytic Activity at High Temperatures" (externer Link, öffnet neues Fenster)